Comprehensive Study Guide D345
1
Summary WGU D345 Comprehensive Study Guide:
Dr Cole Remediation for OA | latest Update with
complete solutions.
Section 1 Highlight Guide
• 1. Neurotransmitters: know all the
neurotransmitters, the role of various
neurotransmitters in various diagnosis and
symptoms. Recommendation: Make a chart with
various diagnosis and the role various
neurotransmitters play in that diagnosis/symptom.
• The study of the magnitude and variation of drug
response is the definition of pharmacodynamics.
Psychodynamics is the study of
what the body does to a drug and helps explain the
relationship between the dose and response.
o Dopamine produced in substantia nigra and
ventral tegmental area
▪ D: Drive/Drugs
▪ O: psychOsis
▪ P: Prolactin Inhibition
▪ A: Attention
▪ M: Motivation
▪ I: Involuntary Movements
▪ N: Nausea
▪ E: Energy
o Serotonin is produced mostly in Raphe nucleus
▪ DOMAINS: Depression, Obsession,
Migraines, Anxiety, Intestines, Nausea,
and Sexual.
▪ Serotonin Syndrome: Shits and
SHIVERS. Shits(diarrhea),
Shivering, Hyperreflexia, Increased
temperature, Vital sign instability,
Encephalopathy, Restlessness, and
Sweating.
, Comprehensive Study Guide D345
2
o Norepinephrine is produced in locus ceruleus of the pons
▪ Receptors A1, A2, B1, B2, and B3. More blood vessels.
▪ Fight or flight. Sympathetic nervous system.
▪ Concentrating, focusing, burst of energy, increased
BP/HR, mobilizing glucose
o Epinephrine produced by the adrenal glands
▪ More heart
▪ Fight or flight. Sympathetic nervous system.
o Acetylcholine synthesized by the Basal Nucleus of Meynart
▪ Parasympathetic Nervous system. Rest
and Digest. Feed and breed.
o Muscarinic Receptors
, Comprehensive Study Guide D345
3
▪ SLUDGEM. Salivation, Lacrimation,
Urination, Diaphoresis, GI effects, emesis, and
miosis.
o Nicotinic: Muscle contraction and cognition.
o Glutamate
▪ Excitatory. Effects learning, memory, and
thoughts. glutaMATe.
o GABA(y-aminobutyric acid).
▪ Inhibitory. Like a gabber who goes on and on and
puts everyone to sleep.
o Histamine:
▪ antiHISTAmines Help with Insomnia, Stomach acid,
and Allergies.
▪ Insomnia, stomach acid, allergies.
o Dopamine produced in substantia nigra and ventral tegmental
area
o Serotonin is produced mostly in Raphe nucleus
o Norepinephrine is produced in locus ceruleus of the pons
o Epinephrine produced by the adrenal glands
o Acetylcholine synthesized by the Basal Nucleus of Meynart
o Glutamate
o GABA(y-aminobutyric acid).
• 2. Components of a neuron and their role/functions
o Dendrites
o Dendritic Spines
o Soma(cell body)
▪ Contains the nucleus.
o Presynaptic/Post synaptic
• 3. G-Protein linked system
o First messenger passes to the second. In G Link, this is
chemical.
, Comprehensive Study Guide D345
4
1
Summary WGU D345 Comprehensive Study Guide:
Dr Cole Remediation for OA | latest Update with
complete solutions.
Section 1 Highlight Guide
• 1. Neurotransmitters: know all the
neurotransmitters, the role of various
neurotransmitters in various diagnosis and
symptoms. Recommendation: Make a chart with
various diagnosis and the role various
neurotransmitters play in that diagnosis/symptom.
• The study of the magnitude and variation of drug
response is the definition of pharmacodynamics.
Psychodynamics is the study of
what the body does to a drug and helps explain the
relationship between the dose and response.
o Dopamine produced in substantia nigra and
ventral tegmental area
▪ D: Drive/Drugs
▪ O: psychOsis
▪ P: Prolactin Inhibition
▪ A: Attention
▪ M: Motivation
▪ I: Involuntary Movements
▪ N: Nausea
▪ E: Energy
o Serotonin is produced mostly in Raphe nucleus
▪ DOMAINS: Depression, Obsession,
Migraines, Anxiety, Intestines, Nausea,
and Sexual.
▪ Serotonin Syndrome: Shits and
SHIVERS. Shits(diarrhea),
Shivering, Hyperreflexia, Increased
temperature, Vital sign instability,
Encephalopathy, Restlessness, and
Sweating.
, Comprehensive Study Guide D345
2
o Norepinephrine is produced in locus ceruleus of the pons
▪ Receptors A1, A2, B1, B2, and B3. More blood vessels.
▪ Fight or flight. Sympathetic nervous system.
▪ Concentrating, focusing, burst of energy, increased
BP/HR, mobilizing glucose
o Epinephrine produced by the adrenal glands
▪ More heart
▪ Fight or flight. Sympathetic nervous system.
o Acetylcholine synthesized by the Basal Nucleus of Meynart
▪ Parasympathetic Nervous system. Rest
and Digest. Feed and breed.
o Muscarinic Receptors
, Comprehensive Study Guide D345
3
▪ SLUDGEM. Salivation, Lacrimation,
Urination, Diaphoresis, GI effects, emesis, and
miosis.
o Nicotinic: Muscle contraction and cognition.
o Glutamate
▪ Excitatory. Effects learning, memory, and
thoughts. glutaMATe.
o GABA(y-aminobutyric acid).
▪ Inhibitory. Like a gabber who goes on and on and
puts everyone to sleep.
o Histamine:
▪ antiHISTAmines Help with Insomnia, Stomach acid,
and Allergies.
▪ Insomnia, stomach acid, allergies.
o Dopamine produced in substantia nigra and ventral tegmental
area
o Serotonin is produced mostly in Raphe nucleus
o Norepinephrine is produced in locus ceruleus of the pons
o Epinephrine produced by the adrenal glands
o Acetylcholine synthesized by the Basal Nucleus of Meynart
o Glutamate
o GABA(y-aminobutyric acid).
• 2. Components of a neuron and their role/functions
o Dendrites
o Dendritic Spines
o Soma(cell body)
▪ Contains the nucleus.
o Presynaptic/Post synaptic
• 3. G-Protein linked system
o First messenger passes to the second. In G Link, this is
chemical.
, Comprehensive Study Guide D345
4
