5/22/26, 7:12 NUR 2474 Pharmacology Ras
AM
NRSG 210 Pharmacology Final Exam Review (Post-
Midterm) | Rasmussen NRSG210 | Corticosteroids,
Thyroid, Pain Management, Diuretics, Electrolytes &
Key Concepts | Verified Notes.
Corticosteroids and long term treatment
Used to:
-Suppress the inflammatory process.
-Decrease the immune responses.
long term:
-leads to adrenal atrophy from lack of stimulation
-Avoid LIVE vaccines (attenuated)
-Report wt. gain over 2lbs in ONE day
-Oral route best option for chronic vs. acute
Adverse effects of chronic corticosteroids
Suppression of immune system
Decreased inflammatory
responses GI Bleeds/Peptic
Ulcers Osteoporosis
Behavioral changes
Metabolic changes/fat redistribution & fluid retention
Replacement therapy with GLUCOcorticoids
Drug interactions:
-Postassium-wasting drugs
-Anticholinesterase agents
-NO live vaccines
-Toxoids
-Insulin and oral hypoglycemic drugs
-Aloe, senna, cascara, buckthron
Increases effect of:
-erythromycin, keoconazole
1/38
,5/22/26, 7:12 NUR 2474 Pharmacology Ras
AM
Decreases effectiveness of:
-salicyclates, barbibiturates, phenytoin, rifampin
2/38
,5/22/26, 7:12 NUR 2474 Pharmacology Ras
AM
Physiology of thyroid gland
- low blood levels trigger negative feedback
loop Hypothalamus (TRH - thyrotropin
releasing hormone) Anterior pituitary (TSH -
thyroid stimulating hormone) Thyroid (T3 &
T4)
Diagnosis of thyroid disorders
TSH is preferred lab value
-low TSH = GOOD
Primary hypothyroidism=
-low serum T4
-Elevated TSH
Hashimoto thyroiditis
-abnormal levels of antithyroid antibody
Precautions of hypothyroid disorders (pharmacotherapy)
cardiac disease
-acute MI
-Angina pectoris
-Cardiac dysrhythmias
-sensitivity to the drug
-thyrotoxicosis
-adrenal insufficiency
-hypertension
-impaired kidney function
-diabetes
-elderly patients
-treatment of obesity
Drug interactions for hypothyroid disorders
Phenytoin-accelerates the metabolism of levo
-bile-acid sequestrants
-calcium or aluminum containing antacids
-sucralfate
3/38
, 5/22/26, 7:12 NUR 2474 Pharmacology Ras
AM
-warfarin
4/38
AM
NRSG 210 Pharmacology Final Exam Review (Post-
Midterm) | Rasmussen NRSG210 | Corticosteroids,
Thyroid, Pain Management, Diuretics, Electrolytes &
Key Concepts | Verified Notes.
Corticosteroids and long term treatment
Used to:
-Suppress the inflammatory process.
-Decrease the immune responses.
long term:
-leads to adrenal atrophy from lack of stimulation
-Avoid LIVE vaccines (attenuated)
-Report wt. gain over 2lbs in ONE day
-Oral route best option for chronic vs. acute
Adverse effects of chronic corticosteroids
Suppression of immune system
Decreased inflammatory
responses GI Bleeds/Peptic
Ulcers Osteoporosis
Behavioral changes
Metabolic changes/fat redistribution & fluid retention
Replacement therapy with GLUCOcorticoids
Drug interactions:
-Postassium-wasting drugs
-Anticholinesterase agents
-NO live vaccines
-Toxoids
-Insulin and oral hypoglycemic drugs
-Aloe, senna, cascara, buckthron
Increases effect of:
-erythromycin, keoconazole
1/38
,5/22/26, 7:12 NUR 2474 Pharmacology Ras
AM
Decreases effectiveness of:
-salicyclates, barbibiturates, phenytoin, rifampin
2/38
,5/22/26, 7:12 NUR 2474 Pharmacology Ras
AM
Physiology of thyroid gland
- low blood levels trigger negative feedback
loop Hypothalamus (TRH - thyrotropin
releasing hormone) Anterior pituitary (TSH -
thyroid stimulating hormone) Thyroid (T3 &
T4)
Diagnosis of thyroid disorders
TSH is preferred lab value
-low TSH = GOOD
Primary hypothyroidism=
-low serum T4
-Elevated TSH
Hashimoto thyroiditis
-abnormal levels of antithyroid antibody
Precautions of hypothyroid disorders (pharmacotherapy)
cardiac disease
-acute MI
-Angina pectoris
-Cardiac dysrhythmias
-sensitivity to the drug
-thyrotoxicosis
-adrenal insufficiency
-hypertension
-impaired kidney function
-diabetes
-elderly patients
-treatment of obesity
Drug interactions for hypothyroid disorders
Phenytoin-accelerates the metabolism of levo
-bile-acid sequestrants
-calcium or aluminum containing antacids
-sucralfate
3/38
, 5/22/26, 7:12 NUR 2474 Pharmacology Ras
AM
-warfarin
4/38
