CHEMISTRY AND MOLECULAR DIAGNOSTICS 7TH
EDITION BURTIS QUESTIONS AND CORRECT
ANSWERS (VERIFIED ANSWERS Q&A 2026
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1. Which analyte is most commonly used to assess long-term
glycemic control?
A. Plasma glucose
B. Serum insulin
C. HbA1c
D. C-peptide
Rationale: HbA1c reflects average blood glucose over ~2–3
months.
Correct answer: C. HbA1c
2. Which organ is primarily responsible for urea synthesis?
A. Kidney
B. Liver
C. Pancreas
D. Spleen
Rationale: Urea cycle occurs in hepatocytes.
Correct answer: B. Liver
,3. Which specimen is most appropriate for arterial blood gas
analysis?
A. Venous blood
B. Capillary blood
C. Arterial blood
D. Serum
Rationale: Arterial blood reflects oxygenation status accurately.
Correct answer: C. Arterial blood
4. Which electrolyte is the major extracellular cation?
A. Potassium
B. Calcium
C. Sodium
D. Magnesium
Rationale: Sodium dominates extracellular fluid balance.
Correct answer: C. Sodium
5. What is the primary principle of spectrophotometry?
A. Light scattering
B. Absorbance of light by analytes
C. Electrical conductivity
D. Centrifugation speed
Rationale: Measures light absorption at specific wavelengths.
Correct answer: B. Absorbance of light by analytes
,6. Which enzyme is most specific for myocardial injury?
A. ALT
B. CK-MB
C. ALP
D. Amylase
Rationale: CK-MB rises in cardiac muscle damage.
Correct answer: B. CK-MB
7. Which molecule is the primary carrier of oxygen in blood?
A. Albumin
B. Hemoglobin
C. Fibrinogen
D. Globulin
Rationale: Hemoglobin binds and transports oxygen.
Correct answer: B. Hemoglobin
8. Which condition is associated with metabolic acidosis?
A. Vomiting
B. Diarrhea
C. Hypoventilation
D. Hyperaldosteronism
Rationale: Diarrhea causes bicarbonate loss.
Correct answer: B. Diarrhea
, 9. Which test is most specific for pancreatic injury?
A. Lipase
B. ALT
C. AST
D. LDH
Rationale: Lipase is more specific than amylase for pancreas.
Correct answer: A. Lipase
10. What is the normal pH range of blood?
A. 6.8–7.0
B. 7.0–7.2
C. 7.35–7.45
D. 7.5–7.8
Rationale: Physiological blood pH is tightly regulated.
Correct answer: C. 7.35–7.45
11. Which is the primary function of the kidneys?
A. Hormone synthesis only
B. Blood filtration and waste excretion
C. Protein digestion
D. Oxygen transport
Rationale: Kidneys filter plasma and regulate homeostasis.
Correct answer: B. Blood filtration and waste excretion