NR 565 - Advanced
Pharmacology Midterm –
Chamberlain 2026 Exam All
Answers and Illustrations
Given
During what trimester is a pregnant woman most at risk for adverse drug
reactions with potential long term consequences? - ANSWER ✔✔1st
trimester (fetus most at risk d/t rapid growth)
What is BEERS criteria? - ANSWER ✔✔Recommendations of
medications inappropriate for elderly (65 and older), prescriber ultimately
decides
,What is the CYP450 (cytochrome P450) - ANSWER ✔✔liver enzyme
system where medications are metabolized, can either be inducers or
inhibitors and create drug-drug interactions
CYP450 inducers - ANSWER ✔✔Speed up metabolism of drugs
(drug is cleared faster), drug has lesser effect (decrease blood levels of
drug), elevate CYP450 enzymes
CYP450 inducers pneumonic - ANSWER ✔✔"Bullshit Crap GPS
INDUCES rage"
CYP450 inducer drug names - ANSWER ✔✔Barbituates, St John
wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin,
phenobarbital, sulfonylureas
CYP450 inhibitors - ANSWER ✔✔inhibit metabolism, increase blood
levels of medications
CYP450 pneumonic - ANSWER ✔✔"VISA credit card debt INHIBITS
spending on designers like CK to look GQ"
CYP450 inhibitors drug names - ANSWER ✔✔Valproate, isoniazid,
sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit
juice, quinidine
,Physiological changes during pregnancy that impact pharmacodynamics
and pharmacokinetic properties of drugs? - ANSWER ✔✔increase
glomerular filtration rate leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic - ANSWER
✔✔Antiepileptic drugs, antimicrobials such as tetracyclines and
fluoroquinolones, vitamin A in large doses, some anticoagulants, and
hormonal medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in neonates? -
ANSWER ✔✔slow and erratic due to low blood flow in muscles first
few days of life
Why is absorption of medication in the stomach increased in infancy? -
ANSWER ✔✔delayed gastric emptying
Some medications that should be avoided in the pediatric patient? -
ANSWER ✔✔glucocorticoids, discoloration of developing teeth with
3
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2026. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
, tetracyclines, and kernicterus with sulfonamides, levofloxacin
(antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration patient education?
- ANSWER ✔✔dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at higher risk for
adverse drug reactions? - ANSWER ✔✔reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
Pharmacology Midterm –
Chamberlain 2026 Exam All
Answers and Illustrations
Given
During what trimester is a pregnant woman most at risk for adverse drug
reactions with potential long term consequences? - ANSWER ✔✔1st
trimester (fetus most at risk d/t rapid growth)
What is BEERS criteria? - ANSWER ✔✔Recommendations of
medications inappropriate for elderly (65 and older), prescriber ultimately
decides
,What is the CYP450 (cytochrome P450) - ANSWER ✔✔liver enzyme
system where medications are metabolized, can either be inducers or
inhibitors and create drug-drug interactions
CYP450 inducers - ANSWER ✔✔Speed up metabolism of drugs
(drug is cleared faster), drug has lesser effect (decrease blood levels of
drug), elevate CYP450 enzymes
CYP450 inducers pneumonic - ANSWER ✔✔"Bullshit Crap GPS
INDUCES rage"
CYP450 inducer drug names - ANSWER ✔✔Barbituates, St John
wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin,
phenobarbital, sulfonylureas
CYP450 inhibitors - ANSWER ✔✔inhibit metabolism, increase blood
levels of medications
CYP450 pneumonic - ANSWER ✔✔"VISA credit card debt INHIBITS
spending on designers like CK to look GQ"
CYP450 inhibitors drug names - ANSWER ✔✔Valproate, isoniazid,
sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit
juice, quinidine
,Physiological changes during pregnancy that impact pharmacodynamics
and pharmacokinetic properties of drugs? - ANSWER ✔✔increase
glomerular filtration rate leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic - ANSWER
✔✔Antiepileptic drugs, antimicrobials such as tetracyclines and
fluoroquinolones, vitamin A in large doses, some anticoagulants, and
hormonal medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in neonates? -
ANSWER ✔✔slow and erratic due to low blood flow in muscles first
few days of life
Why is absorption of medication in the stomach increased in infancy? -
ANSWER ✔✔delayed gastric emptying
Some medications that should be avoided in the pediatric patient? -
ANSWER ✔✔glucocorticoids, discoloration of developing teeth with
3
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2026. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
, tetracyclines, and kernicterus with sulfonamides, levofloxacin
(antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration patient education?
- ANSWER ✔✔dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at higher risk for
adverse drug reactions? - ANSWER ✔✔reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
