Newest Updated Test Bank for Pathophysiology The Biologic Basis for Disease in
Adults and Children, 8th Edition (2018) by Kathryn L. McCance and Sue E.
Huether
Pathophysiology: The Biologic Basis for Disease in Adults and Children, 8th Edition
– Test Bank (200 Practice Questions)
About this resource: The following 200 multiple-choice questions are compiled
from verified test banks for McCance & Huether's Pathophysiology, 8th Edition .
Each question includes the correct answer and a detailed rationale. The material
is organized by topic, progressing from foundational cellular concepts to multi-
system disorders, reflecting the textbook's structure . All content is for
educational purposes.
Unit I: The Cell (Questions 1-35)
Cellular Biology & Function
1. Which statement best describes the cellular function of metabolic absorption?
A) Cells can produce proteins.
B) Cells can secrete digestive enzymes.
C) Cells can take in and use nutrients.
,D) Cells can synthesize fats.
Rationale: Metabolic absorption refers to the ability of all cells to take in and
utilize nutrients and other substances from their immediate environment .
2. Most of a cell's genetic information, including RNA and DNA, is contained in
the:
A) Mitochondria
B) Ribosome
C) Nucleolus
D) Lysosome
Rationale: The nucleolus is a dense structure within the nucleus containing RNA,
most cellular DNA, and DNA-binding proteins (histones) that regulate genetic
activity .
,3. Which cell component produces hydrogen peroxide (H₂O₂) by using oxygen to
remove hydrogen atoms from specific substrates?
A) Lysosomes
B) Peroxisomes
C) Ribosomes
D) Endosomes
Rationale: Peroxisomes contain oxidative enzymes that use oxygen to remove
hydrogen atoms, producing H₂O₂ as a byproduct .
4. Which cell component is capable of cellular autodigestion when released
during cell injury?
A) Ribosome
, B) Golgi complex
C) Smooth endoplasmic reticulum
D) Lysosomes
Rationale: The lysosomal membrane protects the cytoplasm from powerful
digestive enzymes. Injury causing membrane disruption releases these enzymes,
leading to cellular self-digestion .
5. Which cAMP-mediated response is related to antidiuretic hormone?
A) Increased heart rate and force of contraction
B) Secretion of cortisol
C) Increased retention of water
D) Breakdown of fat
Adults and Children, 8th Edition (2018) by Kathryn L. McCance and Sue E.
Huether
Pathophysiology: The Biologic Basis for Disease in Adults and Children, 8th Edition
– Test Bank (200 Practice Questions)
About this resource: The following 200 multiple-choice questions are compiled
from verified test banks for McCance & Huether's Pathophysiology, 8th Edition .
Each question includes the correct answer and a detailed rationale. The material
is organized by topic, progressing from foundational cellular concepts to multi-
system disorders, reflecting the textbook's structure . All content is for
educational purposes.
Unit I: The Cell (Questions 1-35)
Cellular Biology & Function
1. Which statement best describes the cellular function of metabolic absorption?
A) Cells can produce proteins.
B) Cells can secrete digestive enzymes.
C) Cells can take in and use nutrients.
,D) Cells can synthesize fats.
Rationale: Metabolic absorption refers to the ability of all cells to take in and
utilize nutrients and other substances from their immediate environment .
2. Most of a cell's genetic information, including RNA and DNA, is contained in
the:
A) Mitochondria
B) Ribosome
C) Nucleolus
D) Lysosome
Rationale: The nucleolus is a dense structure within the nucleus containing RNA,
most cellular DNA, and DNA-binding proteins (histones) that regulate genetic
activity .
,3. Which cell component produces hydrogen peroxide (H₂O₂) by using oxygen to
remove hydrogen atoms from specific substrates?
A) Lysosomes
B) Peroxisomes
C) Ribosomes
D) Endosomes
Rationale: Peroxisomes contain oxidative enzymes that use oxygen to remove
hydrogen atoms, producing H₂O₂ as a byproduct .
4. Which cell component is capable of cellular autodigestion when released
during cell injury?
A) Ribosome
, B) Golgi complex
C) Smooth endoplasmic reticulum
D) Lysosomes
Rationale: The lysosomal membrane protects the cytoplasm from powerful
digestive enzymes. Injury causing membrane disruption releases these enzymes,
leading to cellular self-digestion .
5. Which cAMP-mediated response is related to antidiuretic hormone?
A) Increased heart rate and force of contraction
B) Secretion of cortisol
C) Increased retention of water
D) Breakdown of fat
