Review
Please indicate which of the following is true for alpha 1 subtype adrenergic receptors:
a. located on serotonergic terminals
b. located in the sympathetic system where it controls urinary retention
c. signals via stimulation of adenylyl cyclase
d. A and C - correct answer ✔✔b. located in the sympathetic system where it controls urinary
retention
Which of the following disorders is more common in women:
a. Bipolar I
b. GAD
c. MDD
d. All of the above
e. A and B
f. B and C - correct answer ✔✔f. B and C
Please indicate which of the following statement(s) is (are) true:
a. Suicidal ideation is hypothesized to be driven, at least in part, by abnormalities in
norepinephrine tone in the ventral medical prefrontal cortex and the amygdala.
b. Anhedonia is hypothesized to be driven, at least in part, by abnormalities in dopamine tone in
the nucleus accumbens.
, c. Executive dysfunction is hypothesized to be driven, at least in part, by abnormalities in
serotonin tone in the hypothalamus.
d. All of the above
e. A and B
f. B and C - correct answer ✔✔b. Anhedonia is hypothesized to be driven, at least in part, by
abnormalities in dopamine tone in the nucleus accumbens.
Please indicate which of the following is true for the mechanism of action of SARIs:
a. Antagonism of 5HT2A receptor potentiates the inhibitory action of 5HT1A receptor on
glutamate release by some pyramidal neurons
b. Disinhibition of 5HT2A and 5HT2C on DA and NE release
c. Increase serotonin levels via alpha 2 antagonism
d. All of the above
e. A and B
f. A and C - correct answer ✔✔e. A and B
Please indicate which of the following is a risk factor to develop PTSD:
a. Carrying the 5-HTT short allele
b. Earlier age at the time of the traumatic event
c. Bigger hippocampus size
d. All of the above
e. A and B
f. B and C - correct answer ✔✔e. A and B
Please indicate which of the following is true for the monoamine receptor hypothesis: