PATH 3010 Exam 3 UPDATED
QUESTIONS AND CORRECT ANSWERS
How was penicillin discovered? Who were the 3 scientists involved in mass production of penicillin
and what were their roles? Why was penicillin so important in WWII? - CORRECT
ANSWER Discovered by visiting professor Alex Flemming in a lab filled with plates... one of
the plates had a mold with no bacteria growing around it.
"The Oxford Team"
- Chain & Florey were able to purify the compound.
- Used ag waste the grow the mold
Was important in WW1 to treat the soldiers and prevent infections.
What other antibiotics were discussed? - CORRECT ANSWER Cephalosporin (antibacterial)
Griseofulvin (anti-fungal)
What are actinomycetes? Which antibiotics do they make? - CORRECT ANSWER Bacteria
that produce compounds
They make:
- Actinomycin
- Streptomycin
- Chloromycetin
- Tetracycline
What is antibiotic resistance and how does it develop? Why do fungi make antibiotics? - CORRECT
ANSWER Antibiotic resistance is due to: overuse; failure to follow treatment to completion;
drugs in livestock/water supplies/etc.
Antibiotics help fungi with survival and competition
, What is cyclosporine? What does it treat? What has it allowed surgeons to do that could not be done
before it was discovered? - CORRECT ANSWER Cyclosporine- front Tolypocladium inflatum
It affects T-cells (immunosuppressant)
It changed Organ Transplants
What are statins? What do they treat? What edible fungus is known to produce large quantities of
statins? - CORRECT ANSWER Statins are a group of drugs made from fungi.
They reduce the production of cholesterol (helps with heart disease and reduces heart attacks by
45%).
Oyster mushrooms
Who is Otzi the Iceman? What fungi was he discovered with? - CORRECT ANSWER A person
from about 5000ya.
Found with birch polypore and tinder polypore
What are the important active ingredients in Ganoderma lucidum? What are their activities? What are
the fungus's common names? Is this fungus common or rare in nature? Is it cultivated? - CORRECT
ANSWER Beta 1-3 glucan (preventative med)
Ganoderic Acids (steroid hormone with hepatoprotective properties)
Polysaccharides & beta-glucans (boosts the immune system)
"Reishi" (Japan) & "Lingzhi" (China)
It is rate in the wild, but it is cultivated.
QUESTIONS AND CORRECT ANSWERS
How was penicillin discovered? Who were the 3 scientists involved in mass production of penicillin
and what were their roles? Why was penicillin so important in WWII? - CORRECT
ANSWER Discovered by visiting professor Alex Flemming in a lab filled with plates... one of
the plates had a mold with no bacteria growing around it.
"The Oxford Team"
- Chain & Florey were able to purify the compound.
- Used ag waste the grow the mold
Was important in WW1 to treat the soldiers and prevent infections.
What other antibiotics were discussed? - CORRECT ANSWER Cephalosporin (antibacterial)
Griseofulvin (anti-fungal)
What are actinomycetes? Which antibiotics do they make? - CORRECT ANSWER Bacteria
that produce compounds
They make:
- Actinomycin
- Streptomycin
- Chloromycetin
- Tetracycline
What is antibiotic resistance and how does it develop? Why do fungi make antibiotics? - CORRECT
ANSWER Antibiotic resistance is due to: overuse; failure to follow treatment to completion;
drugs in livestock/water supplies/etc.
Antibiotics help fungi with survival and competition
, What is cyclosporine? What does it treat? What has it allowed surgeons to do that could not be done
before it was discovered? - CORRECT ANSWER Cyclosporine- front Tolypocladium inflatum
It affects T-cells (immunosuppressant)
It changed Organ Transplants
What are statins? What do they treat? What edible fungus is known to produce large quantities of
statins? - CORRECT ANSWER Statins are a group of drugs made from fungi.
They reduce the production of cholesterol (helps with heart disease and reduces heart attacks by
45%).
Oyster mushrooms
Who is Otzi the Iceman? What fungi was he discovered with? - CORRECT ANSWER A person
from about 5000ya.
Found with birch polypore and tinder polypore
What are the important active ingredients in Ganoderma lucidum? What are their activities? What are
the fungus's common names? Is this fungus common or rare in nature? Is it cultivated? - CORRECT
ANSWER Beta 1-3 glucan (preventative med)
Ganoderic Acids (steroid hormone with hepatoprotective properties)
Polysaccharides & beta-glucans (boosts the immune system)
"Reishi" (Japan) & "Lingzhi" (China)
It is rate in the wild, but it is cultivated.
