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RN FUNDAMENTALS HESI EXAM 2025 – 450 REAL QUESTIONS & VERIFIED ANSWERS | FUNDAMENTALS OF NURSING TEST BANK

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Pass your RN Fundamentals HESI Exam with confidence using this complete test bank of 450 real exam questions and correct answers. Covering every essential nursing domain—sterile technique and infection control (sterile gloves, indwelling catheters, contact precautions, C. diff, PPE, hand hygiene, central line care), medication administration (subcutaneous heparin, IM injections, insulin, warfarin, digoxin, metformin, albuterol, nitroglycerin, vancomycin, PCA morphine), fluid and electrolyte balance (IV therapy, infiltration vs. phlebitis, blood transfusions, TPN, NG suction, fluid restriction, hyperkalemia, hypokalemia, furosemide), elimination (urinary catheterization, bowel ostomies, enemas, fecal impaction), oxygenation (oxygen delivery devices, chest tubes, tracheostomy care, suctioning, COPD, ARDS, mechanical ventilation), mobility and safety (falls prevention, restraints, hip replacement precautions, traction, compartment syndrome, amputation care, phantom limb pain, transfer techniques), nutrition (dysphagia, low-sodium diet,

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RN FUNDAMENTALS HESI
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RN FUNDAMENTALS HESI

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RN FUNDAMENTALS HESI NEWEST 2025 TEST BANK| 3
VERSIONS (VERSION A, B & C) WITH COMPLETE 450
REAL EXAM QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) GRADED A+ (MOST
RECENT!!)
Question 1

A nurse is preparing to insert an indwelling urinary catheter for a
female patient. Which action demonstrates proper sterile
technique?

A) Open the outer catheter package, then put on sterile gloves
B) Use clean gloves to open the sterile kit, then apply sterile
gloves
C) Apply sterile gloves before opening any sterile supplies
D) Open all sterile packages before applying sterile gloves

Answer: B
Rationale: The nurse should first apply clean gloves to open the
outer packaging of the sterile kit, then remove clean gloves,
perform hand hygiene, and apply sterile gloves. This prevents
contamination of sterile gloves by outer packaging.



1

,Question 2

A patient has an order for enoxaparin (Lovenox) subcutaneously.
Which site is most appropriate?

A) Deltoid muscle
B) Abdomen
C) Vastus lateralis
D) Dorsogluteal

Answer: B
Rationale: Enoxaparin is administered subcutaneously, and the
abdomen (at least 2 inches from the umbilicus) is the preferred
site for anticoagulant injections due to consistent absorption and
less risk of hematoma.



Question 3

A nurse is caring for a patient with a nasogastric (NG) tube set
to continuous suction. Which finding requires immediate
intervention?

A) Residual volume of 150 mL
B) Gastric output that is light yellow


2

,C) pH of aspirate is 3.5
D) NG tube anchoring tape is loose

Answer: D
Rationale: A loose NG tube can migrate and cause aspiration or
ineffective suction. Securement is a priority. Residual up to 500
mL is often acceptable, green/yellow aspirate is normal, and
gastric pH < 4 confirms placement.



Question 4

A patient refuses to take their prescribed morning medications.
What is the nurse’s best response?

A) “You have to take these or sign an Against Medical Advice
form.”
B) “Tell me more about your concerns with these medications.”
C) “I’ll come back later when you are ready.”
D) “Let me call your doctor to report your refusal.”

Answer: B
Rationale: Exploring the patient’s concerns respects autonomy
and may identify reversible barriers (e.g., dysphagia, cost, side



3

, effects). Calling the doctor or threatening AMA is premature
without assessment.



Question 5

A nurse is assessing a patient’s peripheral IV site. Which finding
indicates phlebitis?

A) Cool, pale skin around the insertion site
B) Blood return on aspiration
C) Redness, warmth, and a palpable cord along the vein
D) Infusion running sluggishly

Answer: C
Rationale: Phlebitis presents as redness, warmth, swelling, and a
palpable venous cord. Infiltration causes coolness and pallor.
Sluggish flow alone is nonspecific.



Question 6

A nurse is teaching a patient about a low-sodium diet for
hypertension. Which meal choice indicates understanding?



4

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