“This Is The Only 2026 Released Document All The Others In Market Are Most Probably Fake Or
Old Versions”
AORN PERIOP
101
Final Exam–Aligned Question
Bank
Perioperative Nursing Comprehensive Review
High-Yield | Exam-Focused | Scenario-Based
✔ Periop 101–aligned exam-style multiple-choice questions
✔ Realistic operating room clinical scenarios
✔ Scrub nurse and circulating nurse responsibilities
✔ Surgical safety checklist and time-out verification
✔ Sterile technique, asepsis, and surgical conscience
✔ Instrument, sponge, and sharps count principles
✔ Anesthesia concepts, including malignant hyperthermia
✔ Laser, ESU, and OR fire safety standards
✔ Patient positioning, pressure injury prevention, and tourniquet safety
✔ Infection prevention, sterilization, and disinfection levels
✔ Special population considerations (latex allergy, CJD, obesity, RA)
✔ Embedded correct answers for self-verification
✔ High-yield perioperative decision-making
✔ AND MORE
May 23, 2026
1
“Designed for Registered Nurses & Perioperative Nurse Residents”
,“This Is The Only 2026 Released Document All The Others In Market Are Most Probably Fake Or
Old Versions”
1. Which of the following represents the primary purpose of the surgical safety checklist as
mandated by the World Health Organization?
A) To ensure the surgical team has adequate breaks during lengthy procedures
B) To verify the identity of the patient, the surgical site, and the procedure being
performed >>Correct answer✅✅
C) To inventory all surgical instruments before and after the procedure
D) To document the patient's vital signs every fifteen minutes
2. When transporting a patient from the operating room to the post-anesthesia care unit, which of
the following actions is the highest priority for the perioperative nurse?
A) Ensuring the patient is covered with warm blankets to maintain normothermia
B) Securing the airway and maintaining adequate ventilation during transport >>Correct
answer✅✅
C) Providing the family with an update on the surgical outcome
D) Verifying that the post-anesthesia care unit bed is ready for admission
3. A patient with a known allergy to latex is scheduled for a laparoscopic cholecystectomy. Which
of the following interventions is essential to prevent an anaphylactic reaction?
A) Pre-treating the patient with an antihistamine and corticosteroid
B) Scheduling the patient as the first case of the day to minimize airborne latex >>Correct
answer✅✅
C) Using latex-free gloves and ensuring all equipment in the room is latex-safe
D) Administering a prophylactic dose of epinephrine before induction
4. Which of the following positions is most commonly associated with the risk of peripheral nerve
injury to the ulnar nerve?
A) Lithotomy position
B) Supine position >>Correct answer✅✅
C) Trendelenburg position
D) Prone position
5. The perioperative nurse is performing a surgical hand scrub. Which of the following areas is
considered a non-critical site and should not be scrubbed aggressively?
A) Hands and fingers
B) Forearms
C) Elbows >>Correct answer✅✅
D) Nails
May 23, 2026
2
“Designed for Registered Nurses & Perioperative Nurse Residents”
,“This Is The Only 2026 Released Document All The Others In Market Are Most Probably Fake Or
Old Versions”
6. During a laparoscopic procedure, the surgeon requests the insufflator pressure to be increased
to improve visualization. The perioperative nurse knows that the maximum recommended
intra-abdominal pressure for a healthy adult is:
A) 10 mm Hg
B) 15 mm Hg >>Correct answer✅✅
C) 20 mm Hg
D) 25 mm Hg
7. Which of the following statements regarding the use of electrosurgery units (ESU) is correct?
A) The active electrode must be isolated from the patient's skin to prevent burns.
B) The dispersive pad should be placed over bony prominences to ensure adherence.
C) The patient should not be in contact with metal objects that could serve as an alternate
grounding site. >>Correct answer✅✅
D) Eschar buildup on the active electrode improves the efficiency of the cutting current.
8. A patient undergoing a surgical procedure develops malignant hyperthermia. Which of the
following medications is the specific antidote administered to treat this condition?
A) Dantrolene sodium >>Correct answer✅✅
B) Protamine sulfate
C) Naloxone
D) Flumazenil
9. The surgical team is performing a procedure on a patient with HIV. Which of the following
standard precautions should be strictly adhered to?
A) Double gloving is mandatory for all scrubbed personnel. >>Correct answer✅✅
B) The patient should be placed in a negative pressure room.
C) All instruments must be disposed of after the case.
D) Sharps precautions may be relaxed if the patient's viral load is undetectable.
10. When opening sterile supplies, the perioperative nurse opens the farthest flap of the wrapper
first to prevent:
A) Contamination of the inner contents by reaching over the sterile field >>Correct
answer✅✅
B) The wrapper from tearing
C) Static electricity from building up
D) The sterile field from becoming unbalanced
11. Which of the following wound classifications describes a non-traumatic, uninfected operative
wound in which no inflammation is encountered and the respiratory, alimentary, genital, or
urinary tracts are not entered?
May 23, 2026
3
“Designed for Registered Nurses & Perioperative Nurse Residents”
, “This Is The Only 2026 Released Document All The Others In Market Are Most Probably Fake Or
Old Versions”
A) Class I: Clean >>Correct answer✅✅
B) Class II: Clean-Contaminated
C) Class III: Contaminated
D) Class IV: Dirty-Infected
12. A patient is scheduled for a right total knee replacement. Which of the following actions by the
perioperative nurse most effectively verifies the correct surgical site?
A) Asking the patient to state the procedure and site
B) Reviewing the consent form
C) Marking the surgical site with an indelible marker while the patient is awake and
coherent >>Correct answer✅✅
D) Checking the operative schedule
13. The perioperative nurse is monitoring the patient's fluid balance. Which of the following is an
early sign of hypovolemia?
A) Increased urine output
B) Hypertension
C) Tachycardia >>Correct answer✅✅
D) Bradypnea
14. Which of the following sterilization methods is most appropriate for heat-sensitive, moisture-
sensitive surgical instruments?
A) Steam sterilization
B) Ethylene oxide (EO) gas >>Correct answer✅✅
C) Low-temperature hydrogen peroxide plasma
D) Dry heat sterilization
15. During the intraoperative phase, the circulating nurse notices a break in sterile technique by the
scrub person. What is the immediate action required?
A) Stop the procedure and notify the surgeon immediately
B) Cover the contaminated area with a sterile drape
C) Remove the contaminated item and replace it with a sterile one >>Correct
answer✅✅
D) Document the break in the operative record
16. Which of the following medications is commonly used to reverse the effects of neuromuscular
blocking agents?
A) Neostigmine >>Correct answer✅✅
B) Atropine
C) Succinylcholine
D) Propofol
May 23, 2026
4
“Designed for Registered Nurses & Perioperative Nurse Residents”
Old Versions”
AORN PERIOP
101
Final Exam–Aligned Question
Bank
Perioperative Nursing Comprehensive Review
High-Yield | Exam-Focused | Scenario-Based
✔ Periop 101–aligned exam-style multiple-choice questions
✔ Realistic operating room clinical scenarios
✔ Scrub nurse and circulating nurse responsibilities
✔ Surgical safety checklist and time-out verification
✔ Sterile technique, asepsis, and surgical conscience
✔ Instrument, sponge, and sharps count principles
✔ Anesthesia concepts, including malignant hyperthermia
✔ Laser, ESU, and OR fire safety standards
✔ Patient positioning, pressure injury prevention, and tourniquet safety
✔ Infection prevention, sterilization, and disinfection levels
✔ Special population considerations (latex allergy, CJD, obesity, RA)
✔ Embedded correct answers for self-verification
✔ High-yield perioperative decision-making
✔ AND MORE
May 23, 2026
1
“Designed for Registered Nurses & Perioperative Nurse Residents”
,“This Is The Only 2026 Released Document All The Others In Market Are Most Probably Fake Or
Old Versions”
1. Which of the following represents the primary purpose of the surgical safety checklist as
mandated by the World Health Organization?
A) To ensure the surgical team has adequate breaks during lengthy procedures
B) To verify the identity of the patient, the surgical site, and the procedure being
performed >>Correct answer✅✅
C) To inventory all surgical instruments before and after the procedure
D) To document the patient's vital signs every fifteen minutes
2. When transporting a patient from the operating room to the post-anesthesia care unit, which of
the following actions is the highest priority for the perioperative nurse?
A) Ensuring the patient is covered with warm blankets to maintain normothermia
B) Securing the airway and maintaining adequate ventilation during transport >>Correct
answer✅✅
C) Providing the family with an update on the surgical outcome
D) Verifying that the post-anesthesia care unit bed is ready for admission
3. A patient with a known allergy to latex is scheduled for a laparoscopic cholecystectomy. Which
of the following interventions is essential to prevent an anaphylactic reaction?
A) Pre-treating the patient with an antihistamine and corticosteroid
B) Scheduling the patient as the first case of the day to minimize airborne latex >>Correct
answer✅✅
C) Using latex-free gloves and ensuring all equipment in the room is latex-safe
D) Administering a prophylactic dose of epinephrine before induction
4. Which of the following positions is most commonly associated with the risk of peripheral nerve
injury to the ulnar nerve?
A) Lithotomy position
B) Supine position >>Correct answer✅✅
C) Trendelenburg position
D) Prone position
5. The perioperative nurse is performing a surgical hand scrub. Which of the following areas is
considered a non-critical site and should not be scrubbed aggressively?
A) Hands and fingers
B) Forearms
C) Elbows >>Correct answer✅✅
D) Nails
May 23, 2026
2
“Designed for Registered Nurses & Perioperative Nurse Residents”
,“This Is The Only 2026 Released Document All The Others In Market Are Most Probably Fake Or
Old Versions”
6. During a laparoscopic procedure, the surgeon requests the insufflator pressure to be increased
to improve visualization. The perioperative nurse knows that the maximum recommended
intra-abdominal pressure for a healthy adult is:
A) 10 mm Hg
B) 15 mm Hg >>Correct answer✅✅
C) 20 mm Hg
D) 25 mm Hg
7. Which of the following statements regarding the use of electrosurgery units (ESU) is correct?
A) The active electrode must be isolated from the patient's skin to prevent burns.
B) The dispersive pad should be placed over bony prominences to ensure adherence.
C) The patient should not be in contact with metal objects that could serve as an alternate
grounding site. >>Correct answer✅✅
D) Eschar buildup on the active electrode improves the efficiency of the cutting current.
8. A patient undergoing a surgical procedure develops malignant hyperthermia. Which of the
following medications is the specific antidote administered to treat this condition?
A) Dantrolene sodium >>Correct answer✅✅
B) Protamine sulfate
C) Naloxone
D) Flumazenil
9. The surgical team is performing a procedure on a patient with HIV. Which of the following
standard precautions should be strictly adhered to?
A) Double gloving is mandatory for all scrubbed personnel. >>Correct answer✅✅
B) The patient should be placed in a negative pressure room.
C) All instruments must be disposed of after the case.
D) Sharps precautions may be relaxed if the patient's viral load is undetectable.
10. When opening sterile supplies, the perioperative nurse opens the farthest flap of the wrapper
first to prevent:
A) Contamination of the inner contents by reaching over the sterile field >>Correct
answer✅✅
B) The wrapper from tearing
C) Static electricity from building up
D) The sterile field from becoming unbalanced
11. Which of the following wound classifications describes a non-traumatic, uninfected operative
wound in which no inflammation is encountered and the respiratory, alimentary, genital, or
urinary tracts are not entered?
May 23, 2026
3
“Designed for Registered Nurses & Perioperative Nurse Residents”
, “This Is The Only 2026 Released Document All The Others In Market Are Most Probably Fake Or
Old Versions”
A) Class I: Clean >>Correct answer✅✅
B) Class II: Clean-Contaminated
C) Class III: Contaminated
D) Class IV: Dirty-Infected
12. A patient is scheduled for a right total knee replacement. Which of the following actions by the
perioperative nurse most effectively verifies the correct surgical site?
A) Asking the patient to state the procedure and site
B) Reviewing the consent form
C) Marking the surgical site with an indelible marker while the patient is awake and
coherent >>Correct answer✅✅
D) Checking the operative schedule
13. The perioperative nurse is monitoring the patient's fluid balance. Which of the following is an
early sign of hypovolemia?
A) Increased urine output
B) Hypertension
C) Tachycardia >>Correct answer✅✅
D) Bradypnea
14. Which of the following sterilization methods is most appropriate for heat-sensitive, moisture-
sensitive surgical instruments?
A) Steam sterilization
B) Ethylene oxide (EO) gas >>Correct answer✅✅
C) Low-temperature hydrogen peroxide plasma
D) Dry heat sterilization
15. During the intraoperative phase, the circulating nurse notices a break in sterile technique by the
scrub person. What is the immediate action required?
A) Stop the procedure and notify the surgeon immediately
B) Cover the contaminated area with a sterile drape
C) Remove the contaminated item and replace it with a sterile one >>Correct
answer✅✅
D) Document the break in the operative record
16. Which of the following medications is commonly used to reverse the effects of neuromuscular
blocking agents?
A) Neostigmine >>Correct answer✅✅
B) Atropine
C) Succinylcholine
D) Propofol
May 23, 2026
4
“Designed for Registered Nurses & Perioperative Nurse Residents”
