HESI Pathophysiology Exam Test Bank Prep
HESI PATHOPHYSIOLOGY EXAM TEST BANK PREP NEWEST
2026/2027 ACTUAL EXAM COMPLETE QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+|BRAND NEW VERSION!!
When caring for a patient with a chest tube drainage system, the nurse observes
continuous bubbling in the water seal chamber. What action should the nurse take
first?
A) Clamp the chest tube
B) Increase the suction pressure
C) Check for a leak in the system
D) Notify the healthcare provider immediately - Correct Answer-c) check for a leak
in the system
While auscultating the lungs of a patient, the nurse hears high-pitched, musical
sounds during inspiration. Which condition should the nurse suspect?
A) Pleural effusion
B) Atelectasis
C) Bronchitis
D) Wheezes - Correct Answer-d) wheezes
Which action by the nurse is most appropriate when administering oxygen
therapy to a patient with chronic hypoxemia?
A) Using a non-rebreather mask at 15 L/min
1|Page
, HESI Pathophysiology Exam Test Bank Prep
B) Maintaining an oxygen saturation (SpO2) of 95%
C) Adjusting the oxygen flow rate based on the patient's preference
D) Administering oxygen via a nasal cannula at 2 L/min - Correct Answer-b)
maintaining an oxygen saturation of 95%
The chest X-ray of a patient reveals an area of increased density in the left lower
lobe with air bronchograms. Which condition is consistent with this finding?
A) Atelectasis
B) Pneumonia
C) Pulmonary embolism
D) Pleural effusion - Correct Answer-b) pneumonia
A 2-month-old infant is brought to the pediatrician's office for a routine check-up.
Which immunization should the nurse prioritize administering during this visit?
A) Varicella (chickenpox)
B) Hepatitis B
C) Mumps, measles, and rubella (MMR)
D) Influenza - Correct Answer-b) hep B
Which statement best describes the role of T cells in the immune response?
A) T cells produce antibodies to neutralize pathogens.
B) T cells directly phagocytose invading pathogens.
C) T cells recognize antigens and activate other immune cells.
2|Page
, HESI Pathophysiology Exam Test Bank Prep
D) T cells release histamine to initiate inflammation. - Correct Answer-c) T cells
recognize antigens and activate other immune cells
A patient presents with joint pain, fatigue, and a butterfly-shaped rash across the
cheeks. Based on these symptoms, which autoimmune disorder should the nurse
suspect?
A) Rheumatoid arthritis
B) Systemic lupus erythematosus (SLE)
C) Multiple sclerosis (MS)
D) Type 1 diabetes mellitus - Correct Answer-b) Systemic lupus erythematosus
(SLE)
A patient reports swelling of the lips, tongue, and throat after consuming peanuts.
Which type of hypersensitivity reaction should the nurse suspect?
A) Type I
B) Type II
C) Type III
D) Type IV - Correct Answer-A) type I
When educating a group of adolescents about HIV transmission, which statement
by the nurse is correct?
A) "HIV can be transmitted through casual contact like sharing utensils."
B) "Using condoms during sexual intercourse can greatly reduce the risk of HIV
transmission."
C) "HIV can only be transmitted through blood-to-blood contact."
3|Page
, HESI Pathophysiology Exam Test Bank Prep
D) "HIV cannot be transmitted through needle sharing among intravenous drug
users." - Correct Answer-B) using condoms during sexual intercourse can greatly
reduce the risk of HIV transmission
A patient with a history of chronic illnesses is found to have a decreased CD4+ T
cell count. What condition is the patient most at risk for?
A) Allergic reactions
B) Autoimmune diseases
C) Opportunistic infections
D) Malignancies - Correct Answer-c) opportunistic infections
Which immunoglobulin is primarily responsible for providing passive immunity to
newborns through breast milk?
A) IgA
B) IgD
C) IgE
D) IgM - Correct Answer-A) IgA
According to the Centers for Disease Control and Prevention (CDC), at what age
should the first dose of the human papillomavirus (HPV) vaccine be administered?
A) 2 months
B) 11-12 years
C) 6 months
D) 18 years - Correct Answer-B) 11-12 years
4|Page
HESI PATHOPHYSIOLOGY EXAM TEST BANK PREP NEWEST
2026/2027 ACTUAL EXAM COMPLETE QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+|BRAND NEW VERSION!!
When caring for a patient with a chest tube drainage system, the nurse observes
continuous bubbling in the water seal chamber. What action should the nurse take
first?
A) Clamp the chest tube
B) Increase the suction pressure
C) Check for a leak in the system
D) Notify the healthcare provider immediately - Correct Answer-c) check for a leak
in the system
While auscultating the lungs of a patient, the nurse hears high-pitched, musical
sounds during inspiration. Which condition should the nurse suspect?
A) Pleural effusion
B) Atelectasis
C) Bronchitis
D) Wheezes - Correct Answer-d) wheezes
Which action by the nurse is most appropriate when administering oxygen
therapy to a patient with chronic hypoxemia?
A) Using a non-rebreather mask at 15 L/min
1|Page
, HESI Pathophysiology Exam Test Bank Prep
B) Maintaining an oxygen saturation (SpO2) of 95%
C) Adjusting the oxygen flow rate based on the patient's preference
D) Administering oxygen via a nasal cannula at 2 L/min - Correct Answer-b)
maintaining an oxygen saturation of 95%
The chest X-ray of a patient reveals an area of increased density in the left lower
lobe with air bronchograms. Which condition is consistent with this finding?
A) Atelectasis
B) Pneumonia
C) Pulmonary embolism
D) Pleural effusion - Correct Answer-b) pneumonia
A 2-month-old infant is brought to the pediatrician's office for a routine check-up.
Which immunization should the nurse prioritize administering during this visit?
A) Varicella (chickenpox)
B) Hepatitis B
C) Mumps, measles, and rubella (MMR)
D) Influenza - Correct Answer-b) hep B
Which statement best describes the role of T cells in the immune response?
A) T cells produce antibodies to neutralize pathogens.
B) T cells directly phagocytose invading pathogens.
C) T cells recognize antigens and activate other immune cells.
2|Page
, HESI Pathophysiology Exam Test Bank Prep
D) T cells release histamine to initiate inflammation. - Correct Answer-c) T cells
recognize antigens and activate other immune cells
A patient presents with joint pain, fatigue, and a butterfly-shaped rash across the
cheeks. Based on these symptoms, which autoimmune disorder should the nurse
suspect?
A) Rheumatoid arthritis
B) Systemic lupus erythematosus (SLE)
C) Multiple sclerosis (MS)
D) Type 1 diabetes mellitus - Correct Answer-b) Systemic lupus erythematosus
(SLE)
A patient reports swelling of the lips, tongue, and throat after consuming peanuts.
Which type of hypersensitivity reaction should the nurse suspect?
A) Type I
B) Type II
C) Type III
D) Type IV - Correct Answer-A) type I
When educating a group of adolescents about HIV transmission, which statement
by the nurse is correct?
A) "HIV can be transmitted through casual contact like sharing utensils."
B) "Using condoms during sexual intercourse can greatly reduce the risk of HIV
transmission."
C) "HIV can only be transmitted through blood-to-blood contact."
3|Page
, HESI Pathophysiology Exam Test Bank Prep
D) "HIV cannot be transmitted through needle sharing among intravenous drug
users." - Correct Answer-B) using condoms during sexual intercourse can greatly
reduce the risk of HIV transmission
A patient with a history of chronic illnesses is found to have a decreased CD4+ T
cell count. What condition is the patient most at risk for?
A) Allergic reactions
B) Autoimmune diseases
C) Opportunistic infections
D) Malignancies - Correct Answer-c) opportunistic infections
Which immunoglobulin is primarily responsible for providing passive immunity to
newborns through breast milk?
A) IgA
B) IgD
C) IgE
D) IgM - Correct Answer-A) IgA
According to the Centers for Disease Control and Prevention (CDC), at what age
should the first dose of the human papillomavirus (HPV) vaccine be administered?
A) 2 months
B) 11-12 years
C) 6 months
D) 18 years - Correct Answer-B) 11-12 years
4|Page
