NURl 210/l NUR210l Examl 4l –l Principlesl
ofl Pharmacologyl Guidel |l Galenl (Latestl
2026/l 2027l Update)l 100%l Verifiedl
Questionsl &l Answersl |l Gradel A
Q:l Gentamicin
Answer:
-l Aminoglycosides
-l Use
Morel seriousl infections
Givenl IV
Veryl strongl antibiotic,l usuallyl administeredl onlyl inl hospital;l obtainl C&Sl beforel firstl
dose
-l assessl Peakl andl troughl (whenl patientl onl med)
Q:l Gentamicinl SE/AR
Answer:
-l Confusion/tremors/headache/GIl distress
-l Allergy
-l Superinfection
-l Ototoxicityl ("ears")
-l Bloodl dyscrasiasl (damagesl platelet,l RBC's,l WBC's)
-l Nephrotoxicity
-l SJS
Q:l Gentamicinl interactions/contraindications
Answer:
-l Warfarinl (nol platelets...)
,-l Renall disease
-l OLDERl ADULTSl -l Onlyl usel asl lastl resort
Q:l Ciprofloxacinl &l Levofloxacin)
Answer:
-l Fluoroquinolones
-l Uses:
Severel infections
longerl half-life,l effectl longerl evenl afterl dosel completed
Q:l Fluoroquinolonesl -l Ciprofloxacinl SE/AR
Answer:
-l GIl upset
-l CNSl issuesl -l HA,l dizziness,l tremors,l nightmares
-l Photosensitivity
-l Spontaneousl TENDONl RUPTURE!
-l Bradycardial (cardiotoxic)
-l Bloodl dyscrasial -l RBCs,l WBCs,l platelets
-l Superinfection
-l Hepatotoxicityl &l Nephrotoxicity
Q:l Ciprofloxacinl andl bloodl glucose
Answer:
mayl increasel effectsl ofl orall hypoglycemicl medications,l sol patientsl takingl thesel shouldl
bel advisedl tol monitorl seruml glucosel levelsl closely
Q:l Trimethoprim-Sulfamethoxazolel (TMP-SMZ)
Answer:
-l Sulfonamide
,-l Synergisticl effect;l bothl drugsl togetherl causel bacteriall resistancel tol developl
significantlyl slower.
-l Usedl for
MRSA
UTI
Alternativel therapyl forl patientsl allergicl tol penicillin/cephalosporins
-l Routes:
Oral,l IV,l topical,l ophthalmicl ("pinkl eye")
Q:l Trimethoprim-Sulfamethoxazolel SE/AR
Answer:
-l GIl distress,l stomatitis
-l Photosensitivityl -l avoidl exposurel tol sunlightl &l applyl sunblock/protection
-l Hypoglycemial (rememberl glipizide)
-l Bloodl dyscrasiasl (RBC's,l WBC's,l platelets)
-l Crystallurial canl leadl tol renall failure;l monitorl urinel output,l labs
-l Stevens-Johnsonl syndrome
Q:l Trimethoprim-Sulfamethoxazolel contraindications/interactions
Answer:
-l Renal/liverl disease
-l Anemia
-l Caution:
olderl adults
Diabetes
-l Increasel bleedingl w/l warfarin
-l Increasesl effectl ofl hypoglycemic
-l Increasesl digoxinl level
Q:l Trimethopriml andl Sulfamethoxazolel nursingl interventions
, Answer:
-l Obtainl Cl &l S
-l Bestl givenl onl emptyl stomachl w/l fulll glassl ofl water
-l Increasel fluidl intakel tol atl leastl 2000l mL/day
-l Monitorl Il &l O
-l Monitorl VS
-l Monitorl forl bleeding,l CBC,l andl renall function
-l Monitorl forl rash,l superinfection
-l Avoidl duringl thirdl trimesterl (teratogenic)
Q:l Trimethopriml andl Sulfamethoxazolel teaching
Answer:
-l Increasel fluidsl tol severall quartsl al day
-l nol antacidsl w/l medl (orl any)
-l Warnl patientl ifl allergicl tol otherl sulfal drugsl mayl bel allergicl tol thisl onel (orall
hypoglycemicsl -l sulfonylureas)
-l Teachl sidel effectsl &l howl tol minimizel them
-l Teachl adversel reactionsl tol reportl suchl asl bruisingl orl bleeding
-l Wearl sunglassesl &l sunblockl whenl outdoors
Q:l Silverl sulfadiazine
Answer:
-l Silverl -l naturall antimicrobial
-l Treatmentl ofl burnsl andl sometimesl skinl ulcers
Q:l Viruses
Answer:
-l Morel difficultl tol killl thanl bacteria/fungusl bcuzl theyl livel insidel hostl cell
-l Mainlyl minimizel symptoms/l decreasel lengthl ofl illness
Q:l Acyclovir
ofl Pharmacologyl Guidel |l Galenl (Latestl
2026/l 2027l Update)l 100%l Verifiedl
Questionsl &l Answersl |l Gradel A
Q:l Gentamicin
Answer:
-l Aminoglycosides
-l Use
Morel seriousl infections
Givenl IV
Veryl strongl antibiotic,l usuallyl administeredl onlyl inl hospital;l obtainl C&Sl beforel firstl
dose
-l assessl Peakl andl troughl (whenl patientl onl med)
Q:l Gentamicinl SE/AR
Answer:
-l Confusion/tremors/headache/GIl distress
-l Allergy
-l Superinfection
-l Ototoxicityl ("ears")
-l Bloodl dyscrasiasl (damagesl platelet,l RBC's,l WBC's)
-l Nephrotoxicity
-l SJS
Q:l Gentamicinl interactions/contraindications
Answer:
-l Warfarinl (nol platelets...)
,-l Renall disease
-l OLDERl ADULTSl -l Onlyl usel asl lastl resort
Q:l Ciprofloxacinl &l Levofloxacin)
Answer:
-l Fluoroquinolones
-l Uses:
Severel infections
longerl half-life,l effectl longerl evenl afterl dosel completed
Q:l Fluoroquinolonesl -l Ciprofloxacinl SE/AR
Answer:
-l GIl upset
-l CNSl issuesl -l HA,l dizziness,l tremors,l nightmares
-l Photosensitivity
-l Spontaneousl TENDONl RUPTURE!
-l Bradycardial (cardiotoxic)
-l Bloodl dyscrasial -l RBCs,l WBCs,l platelets
-l Superinfection
-l Hepatotoxicityl &l Nephrotoxicity
Q:l Ciprofloxacinl andl bloodl glucose
Answer:
mayl increasel effectsl ofl orall hypoglycemicl medications,l sol patientsl takingl thesel shouldl
bel advisedl tol monitorl seruml glucosel levelsl closely
Q:l Trimethoprim-Sulfamethoxazolel (TMP-SMZ)
Answer:
-l Sulfonamide
,-l Synergisticl effect;l bothl drugsl togetherl causel bacteriall resistancel tol developl
significantlyl slower.
-l Usedl for
MRSA
UTI
Alternativel therapyl forl patientsl allergicl tol penicillin/cephalosporins
-l Routes:
Oral,l IV,l topical,l ophthalmicl ("pinkl eye")
Q:l Trimethoprim-Sulfamethoxazolel SE/AR
Answer:
-l GIl distress,l stomatitis
-l Photosensitivityl -l avoidl exposurel tol sunlightl &l applyl sunblock/protection
-l Hypoglycemial (rememberl glipizide)
-l Bloodl dyscrasiasl (RBC's,l WBC's,l platelets)
-l Crystallurial canl leadl tol renall failure;l monitorl urinel output,l labs
-l Stevens-Johnsonl syndrome
Q:l Trimethoprim-Sulfamethoxazolel contraindications/interactions
Answer:
-l Renal/liverl disease
-l Anemia
-l Caution:
olderl adults
Diabetes
-l Increasel bleedingl w/l warfarin
-l Increasesl effectl ofl hypoglycemic
-l Increasesl digoxinl level
Q:l Trimethopriml andl Sulfamethoxazolel nursingl interventions
, Answer:
-l Obtainl Cl &l S
-l Bestl givenl onl emptyl stomachl w/l fulll glassl ofl water
-l Increasel fluidl intakel tol atl leastl 2000l mL/day
-l Monitorl Il &l O
-l Monitorl VS
-l Monitorl forl bleeding,l CBC,l andl renall function
-l Monitorl forl rash,l superinfection
-l Avoidl duringl thirdl trimesterl (teratogenic)
Q:l Trimethopriml andl Sulfamethoxazolel teaching
Answer:
-l Increasel fluidsl tol severall quartsl al day
-l nol antacidsl w/l medl (orl any)
-l Warnl patientl ifl allergicl tol otherl sulfal drugsl mayl bel allergicl tol thisl onel (orall
hypoglycemicsl -l sulfonylureas)
-l Teachl sidel effectsl &l howl tol minimizel them
-l Teachl adversel reactionsl tol reportl suchl asl bruisingl orl bleeding
-l Wearl sunglassesl &l sunblockl whenl outdoors
Q:l Silverl sulfadiazine
Answer:
-l Silverl -l naturall antimicrobial
-l Treatmentl ofl burnsl andl sometimesl skinl ulcers
Q:l Viruses
Answer:
-l Morel difficultl tol killl thanl bacteria/fungusl bcuzl theyl livel insidel hostl cell
-l Mainlyl minimizel symptoms/l decreasel lengthl ofl illness
Q:l Acyclovir
