APPLIED PATHOPHYSIOLOGY FOR THE ADVANCED PRACTICE NURSE, FIRST EDITION LUCIE
DLUGASCH, LACHEL STORY
CHAPTER 1 ASSESSMENT QUIZ
Chapter: Chapter 01 - Quiz
Multiple Choice
1. Single nucleotide polymorphisms are best described as:
A) disease-causing genetic mutations.
B) variations on a single DNA base pair.
C) a number of copies on a particular gene that varies.
D) base pairs that alter gene expression.
Ans: B
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
,Title: Cellular Function
2. Which of the following are characteristic of malignant cells?
A) Anaplastic, proliferate, and nonfunctioning
B) Well differentiated and nonfunctioning
C) Anaplastic, encapsulated, and functioning
D) Some differentiation, evade apoptosis, and functioning
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
3. A patient has pancreatic cancer and has a RAS proto-oncogene mutation. This oncogene affects cells
by:
A) suppressing cellular growth and division.
B) turning off protein transcription.
C) allowing the cell to gain function such as proliferation.
D) destroying cellular repair mechanisms.
Ans: C
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
4. A mutation of the breast carcinoma 1 and 2 (BRCA1 and BRCA2) gene associated with cancer of the
breast and ovaries will result in cell:
A) loss of tumor suppressor function.
B) gain of tumor suppressor function.
C) accelerated hyperplasia.
D) increase in protein transcription.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
5. Epigenetics is the field of science that evaluates:
A) changes in underlying DNA sequence.
B) single nucleotide polymorphism development.
C) copy number variant development.
D) mechanism of activation and deactivation of genes.
Ans: D
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
,6. Dysplasia of epithelial cells sometimes results from:
A) excessive sodium intake.
B) chronic irritation or inflammation.
C) increased enzyme synthesis.
D) apoptosis.
Ans: B
Complexity: Easy
Ahead: Cellular Adaptation and Damage
Subject: Chapter 1
Title: Cellular Function
7. Which of the following types of gangrene is usually a result of arterial occlusion?
A) Necrosis
B) Dry
C) Wet
D) Gas
Ans: D
Complexity: Easy
Ahead: Cellular Adaptation and Damage
Subject: Chapter 1
Title: Cellular Function
8. A metastatic tumor is one that:
A) needs an adequate blood supply to survive.
B) shows slow expansion and well-differentiated cells.
C) remains active to survive.
D) invades deeply into the tissue where it arose.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
9. An example of a test that is used for cancer screening (asymptomatic test) is:
A) cytology (pap) smear.
B) endometrial (uterine) biopsy.
C) magnetic resonance imaging of the lungs.
D) thyroid cancer blood tests.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
, 10. Enzymes that use oxidation to convert food materials into energy are found in sausage-shaped
structures called:
A) secretory vesicles.
B) ribosomes.
C) mitochondria.
D) Golgi apparatus.
Ans: C
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
11. Protein hormones and enzymes are
stored in the _ , awaiting signals to be released into the
cell.
A) food vacuole
B) Golgi complex
C) rough endoplasmic reticulum
D) secretory vesicles
Ans: D
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
12. Low serum albumin levels (hypoalbuminemia) can cause edema because:
A) oncotic pressure increases.
B) oncotic pressure decreases.
C) osmotic pressure increases.
D) hydrostatic pressure decreases.
Ans: B
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
13. Neurotransmitters are packaged into vesicles and then fuse with the cell membrane for release. This
is an example of:
A) pinocytosis.
B) phagocytosis.
C) exocytosis.
DLUGASCH, LACHEL STORY
CHAPTER 1 ASSESSMENT QUIZ
Chapter: Chapter 01 - Quiz
Multiple Choice
1. Single nucleotide polymorphisms are best described as:
A) disease-causing genetic mutations.
B) variations on a single DNA base pair.
C) a number of copies on a particular gene that varies.
D) base pairs that alter gene expression.
Ans: B
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
,Title: Cellular Function
2. Which of the following are characteristic of malignant cells?
A) Anaplastic, proliferate, and nonfunctioning
B) Well differentiated and nonfunctioning
C) Anaplastic, encapsulated, and functioning
D) Some differentiation, evade apoptosis, and functioning
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
3. A patient has pancreatic cancer and has a RAS proto-oncogene mutation. This oncogene affects cells
by:
A) suppressing cellular growth and division.
B) turning off protein transcription.
C) allowing the cell to gain function such as proliferation.
D) destroying cellular repair mechanisms.
Ans: C
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
4. A mutation of the breast carcinoma 1 and 2 (BRCA1 and BRCA2) gene associated with cancer of the
breast and ovaries will result in cell:
A) loss of tumor suppressor function.
B) gain of tumor suppressor function.
C) accelerated hyperplasia.
D) increase in protein transcription.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
5. Epigenetics is the field of science that evaluates:
A) changes in underlying DNA sequence.
B) single nucleotide polymorphism development.
C) copy number variant development.
D) mechanism of activation and deactivation of genes.
Ans: D
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
,6. Dysplasia of epithelial cells sometimes results from:
A) excessive sodium intake.
B) chronic irritation or inflammation.
C) increased enzyme synthesis.
D) apoptosis.
Ans: B
Complexity: Easy
Ahead: Cellular Adaptation and Damage
Subject: Chapter 1
Title: Cellular Function
7. Which of the following types of gangrene is usually a result of arterial occlusion?
A) Necrosis
B) Dry
C) Wet
D) Gas
Ans: D
Complexity: Easy
Ahead: Cellular Adaptation and Damage
Subject: Chapter 1
Title: Cellular Function
8. A metastatic tumor is one that:
A) needs an adequate blood supply to survive.
B) shows slow expansion and well-differentiated cells.
C) remains active to survive.
D) invades deeply into the tissue where it arose.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
9. An example of a test that is used for cancer screening (asymptomatic test) is:
A) cytology (pap) smear.
B) endometrial (uterine) biopsy.
C) magnetic resonance imaging of the lungs.
D) thyroid cancer blood tests.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
, 10. Enzymes that use oxidation to convert food materials into energy are found in sausage-shaped
structures called:
A) secretory vesicles.
B) ribosomes.
C) mitochondria.
D) Golgi apparatus.
Ans: C
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
11. Protein hormones and enzymes are
stored in the _ , awaiting signals to be released into the
cell.
A) food vacuole
B) Golgi complex
C) rough endoplasmic reticulum
D) secretory vesicles
Ans: D
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
12. Low serum albumin levels (hypoalbuminemia) can cause edema because:
A) oncotic pressure increases.
B) oncotic pressure decreases.
C) osmotic pressure increases.
D) hydrostatic pressure decreases.
Ans: B
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
13. Neurotransmitters are packaged into vesicles and then fuse with the cell membrane for release. This
is an example of:
A) pinocytosis.
B) phagocytosis.
C) exocytosis.
