WGU D115 Advanced Pathophysiology Practice Test
Questions and Correct Answers with Complete Solution
| New Update 2026/27 | Graded A+
1. What condition is characterized by the reduction of red blood cells, white blood cells,
and platelets in the blood?
Anemia
Thrombocytopenia
Leukopenia
Pancytopenia
2. How are the RBC indices affected in patients with pernicious anemia?
Correct answer
3. If a child is diagnosed with delayed puberty due to physiologic delays in maturation,
what would be the most appropriate management approach?
Conduct genetic testing for underlying disorders.
Monitor growth and development over time.
Refer to a specialist for surgical intervention.
Initiate hormone replacement therapy immediately.
,4. Describe how pulmonary congestion manifests in patients with left-sided heart
failure.
Pulmonary congestion leads to fluid accumulation in the lungs, causing
difficulty in breathing.
Pulmonary congestion causes a decrease in heart rate.
Pulmonary congestion results in increased blood flow to the extremities.
Pulmonary congestion is characterized by systemic edema.
5. What has to happen for ovulation to occur?
Increase of progesterone
Increase of LH
Decrease of progesterone
Decrease of LH
6. The 2 major risk factors for Type II diabetes mellitus are:
Family history (Genetics) & Obesity
Being young & Family history (Genetics)
7. What are the constitutional symptoms associated with chronic lymphocytic
leukemia?
Fever, bone pain, and swollen joints
Chest pain, shortness of breath, and palpitations
Severe headaches, visual disturbances, and seizures
, Night sweats, unintentional weight loss, and fatigue with painless lymphadenopathy
8. If a patient has a deficiency in intrinsic factor, what condition might they develop as
a result?
Pernicious anemia.
Asthma.
Heart failure.
Diabetes mellitus.
9. A 23-year-old male presents with severe sore throat and a 'hot potato' sounding
voice. He is febrile at 101° Fahrenheit with mild unilateral tonsillar edema. This most
likely represents a(n):
Mononucleosis
Acute tonsillitis
Tonsillar Concretions
Peritonsillar Abscess
10. Which of the following is NOT a risk factor for endometrial cancer?
Advancing age, greater than 50 years
Unopposed estrogen use
Oral contraceptive use
Obesity
11. Which symptom is commonly associated with left-sided heart failure?
, Dyspnea
Cyanosis
Jaundice
Palpitations
12. Which macronutrient is primarily responsible for raising blood glucose levels after a
meal in patients with type 2 diabetes?
Fiber
Fat
Carbohydrate
Protein
13. An older adult patient has a diagnosis of left sided heart failure. The FNP would
identify what common condition associated with heart failure?
Correct answer
14. A nurse is caring for a patient with left-sided heart failure. Which symptom is most
likely to be observed?
Pulmonary congestion
Ascites
Jugular vein distension
Questions and Correct Answers with Complete Solution
| New Update 2026/27 | Graded A+
1. What condition is characterized by the reduction of red blood cells, white blood cells,
and platelets in the blood?
Anemia
Thrombocytopenia
Leukopenia
Pancytopenia
2. How are the RBC indices affected in patients with pernicious anemia?
Correct answer
3. If a child is diagnosed with delayed puberty due to physiologic delays in maturation,
what would be the most appropriate management approach?
Conduct genetic testing for underlying disorders.
Monitor growth and development over time.
Refer to a specialist for surgical intervention.
Initiate hormone replacement therapy immediately.
,4. Describe how pulmonary congestion manifests in patients with left-sided heart
failure.
Pulmonary congestion leads to fluid accumulation in the lungs, causing
difficulty in breathing.
Pulmonary congestion causes a decrease in heart rate.
Pulmonary congestion results in increased blood flow to the extremities.
Pulmonary congestion is characterized by systemic edema.
5. What has to happen for ovulation to occur?
Increase of progesterone
Increase of LH
Decrease of progesterone
Decrease of LH
6. The 2 major risk factors for Type II diabetes mellitus are:
Family history (Genetics) & Obesity
Being young & Family history (Genetics)
7. What are the constitutional symptoms associated with chronic lymphocytic
leukemia?
Fever, bone pain, and swollen joints
Chest pain, shortness of breath, and palpitations
Severe headaches, visual disturbances, and seizures
, Night sweats, unintentional weight loss, and fatigue with painless lymphadenopathy
8. If a patient has a deficiency in intrinsic factor, what condition might they develop as
a result?
Pernicious anemia.
Asthma.
Heart failure.
Diabetes mellitus.
9. A 23-year-old male presents with severe sore throat and a 'hot potato' sounding
voice. He is febrile at 101° Fahrenheit with mild unilateral tonsillar edema. This most
likely represents a(n):
Mononucleosis
Acute tonsillitis
Tonsillar Concretions
Peritonsillar Abscess
10. Which of the following is NOT a risk factor for endometrial cancer?
Advancing age, greater than 50 years
Unopposed estrogen use
Oral contraceptive use
Obesity
11. Which symptom is commonly associated with left-sided heart failure?
, Dyspnea
Cyanosis
Jaundice
Palpitations
12. Which macronutrient is primarily responsible for raising blood glucose levels after a
meal in patients with type 2 diabetes?
Fiber
Fat
Carbohydrate
Protein
13. An older adult patient has a diagnosis of left sided heart failure. The FNP would
identify what common condition associated with heart failure?
Correct answer
14. A nurse is caring for a patient with left-sided heart failure. Which symptom is most
likely to be observed?
Pulmonary congestion
Ascites
Jugular vein distension
