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COMSAE Phase 2 Form 104 Questions and Correct Answers

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Prepare effectively for the COMSAE Phase 2 Form 104 assessment with this structured set of exam-style questions and accurate answers designed to reflect the clinical reasoning and format of osteopathic medical board examinations. This resource strengthens core clinical competencies across internal medicine, surgery, pediatrics, obstetrics and gynecology, psychiatry, emergency medicine, and preventive care. It emphasizes diagnosis, patient management, interpretation of clinical findings, and evidence-based decision-making. Ideal for osteopathic medical students preparing for COMLEX-USA Level 2 and COMSAE self-assessment exams seeking improved clinical readiness and exam performance.

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COMSAE PHASE 2 FORM 104
Course
COMSAE PHASE 2 FORM 104

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COMSAE PHASE 2 FORM 104 QUESTIONS AND
CORRECT ANSWERS (VERIFIED ANSWERS) Q&A
2026 |INSTANT DOWNLOAD PDF

1. A 65-year-old man presents with chest pain radiating to the
left arm. Which enzyme is most specific for myocardial
infarction?
A. AST
B. LDH-1
C. Troponin I
D. CK-MB
Rationale: Troponin I is the most sensitive and specific marker
for myocardial injury and remains elevated longer than CK-MB.
Correct Answer: C. Troponin I


2. Which organism is the most common cause of community-
acquired pneumonia?
A. Klebsiella pneumoniae
B. Streptococcus pneumoniae
C. Mycoplasma pneumoniae
D. Legionella pneumophila
Rationale: Streptococcus pneumoniae remains the most
common cause of community-acquired pneumonia in adults.
Correct Answer: B. Streptococcus pneumoniae

,3. A patient has fatty acid oxidation defect. Which enzyme is
most likely deficient?
A. Carnitine palmitoyltransferase I
B. Hexokinase
C. Pyruvate dehydrogenase
D. Glucose-6-phosphatase
Rationale: CPT I is required for transport of long-chain fatty
acids into mitochondria for β-oxidation.
Correct Answer: A. Carnitine palmitoyltransferase I


4. Which vitamin deficiency causes Wernicke-Korsakoff
syndrome?
A. Vitamin B1 (Thiamine)
B. Vitamin B6
C. Vitamin B12
D. Vitamin C
Rationale: Thiamine deficiency leads to Wernicke
encephalopathy and Korsakoff psychosis.
Correct Answer: A. Vitamin B1 (Thiamine)


5. Which hormone increases calcium reabsorption in the
kidney?

,A. Calcitonin
B. Parathyroid hormone
C. Aldosterone
D. ADH
Rationale: PTH increases calcium reabsorption in distal renal
tubules.
Correct Answer: B. Parathyroid hormone


6. Which cell type produces antibodies?
A. T helper cells
B. Plasma cells
C. Macrophages
D. Neutrophils
Rationale: Plasma cells are differentiated B cells that secrete
antibodies.
Correct Answer: B. Plasma cells


7. Which pathogen is associated with “rice-water stools”?
A. Shigella dysenteriae
B. Vibrio cholerae
C. Salmonella typhi
D. E. coli O157:H7

, Rationale: Vibrio cholerae causes profuse watery diarrhea
described as rice-water stools.
Correct Answer: B. Vibrio cholerae


8. Which artery is most commonly involved in myocardial
infarction?
A. Left circumflex artery
B. Right coronary artery
C. Left anterior descending artery
D. Posterior descending artery
Rationale: LAD artery occlusion causes anterior wall MI and is
most common.
Correct Answer: C. Left anterior descending artery


9. Which electrolyte imbalance causes peaked T waves on
ECG?
A. Hypokalemia
B. Hyperkalemia
C. Hypercalcemia
D. Hypocalcemia
Rationale: Hyperkalemia causes peaked T waves due to altered
cardiac conduction.
Correct Answer: B. Hyperkalemia

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COMSAE PHASE 2 FORM 104
Course
COMSAE PHASE 2 FORM 104

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Uploaded on
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Written in
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Type
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