CORRECT Answers
When and how to administer Clopidogrel (Plavix) PO OD at the same time each day.
When is Plavix used? After heart surgery or stent implant to prevent platelet aggregation.
Plavix care considerations -Avoid grapefruit
-Monitor for s/s of stroke and MI and bleeding
-Do NOT stop abruptly
What other medication is Plavix often combined with? Aspirin
Hx to watchout for when giving Plavix? -Stroke
-MI
-Surgery
-Ulcers
-Liver injury
-Trauma
-Bleeding disorders
Things to avoid when on Clopidogrel? -Contact sports
-Razors
-Nail clippers
-ETOH
-Pregnancy
Drug interactions with Clopidogrel? -NSAIDS (increase bleed risk)
-tipranavir
-PPI's
-Antifungals
-Repaglinide
, Purpose of Rh immune globulin? -Treatment of ITP in Rh+ pt's
-If a pt recieves Rh+ blood and is Rh-
-An Rh- mother with an Rh+ fetus
How does Rh Immune Globulin work? Preventing antibody formation in the affected individual.
Pt's to avoid with Rh immune globulin? -Peds
-Anemia
-Clotting disorders
-DIC
-Pulmonary disorders
-Atherosclerosis
-Stroke
-Hemolysis
-IgA deficiency
-Diabetes
Avoid this when giving Rh immune globulin... Live vaccines (for 3 months)
Side effects of Rh immune globulin> -S/S of stroke
-S/S of MI
-Wgt gain
What is Digoxin used to treat? -Heart failure
-Afib
-Other rhythm irregularities
Routes of admin. for Digoxin (Lanoxin) -Oral solution (0.05mg/ml)
-Inj. IV (0.1 and 0.25mg/mL)
-Tab. (0.0625 mg (Lanoxin only) (adult only)
(0.125 mg)
(0.1875 mg (Lanoxin only) (adult only)
(0.25 mg)
Must do prior to Digoxin admin.? Check the apical HR, hold if <60!!!
Is Digoxin safe in peds? What about Lanoxin? Yes
No
Dosing modifications for Digoxin? -Renal clearance and serum levels
-Body weight
Common Digoxin S/E? -Dizziness
-Mental disturbances
-Diarrhea
-HNV (Headache/Nausea/Vomiting)
-Red, bumpy rash
Common Digoxin interactions? -Erythromycin and tetracycline
-Antiarrhythmics (amiodarone)
-CCB's
-Antacids
-Hawthorn
-Licorice