BIOL 2117 COMPREHENSIVE EXAM STUDY
GUIDE TEST PAPER QUESTIONS AND
SOLUTIONS 2026
◉ A typical home pregnancy test is a lateral flow test that detects
human chorionic gonadotrophin in urine.
Answers:
True
False
Answer: true
◉ CD8 cells can be detected in host tissue by using immunostaining.
Answers:
True
False
Answer: true
◉ Double immunodiffusion is also known as which of the following?
Answers:
flocculation assay
Ouchterlony assay
,precipitin ring test
radial immunodiffusion assay
Answer: Ouchterlony assay
◉ Test sensitivity is defined as which of the following?
Answers:
the probability that an individual will have a false-positive test result
the probability that an individual with an infection will test positive
the probability that an individual with an infection will test negative
the probability that a test will detect multiple antigens
simultaneously
Answer: the probability that an individual with an infection will test
positive
◉ Lateral flow tests are inexpensive and easy to perform, which has
enabled the development of a wide range of diagnostic tests for
home use based upon this technology.
Answers:
True
False
Answer: true
,◉ Why would a spectrophotometer be helpful in interpreting the
results of a sandwich ELISA?
Answers:
It would allow for visualization of the antibody-antigen complex.
It would allow one to use a single test to differentiate previous
exposure from acute infection.
It would be faster, although less sensitive.
It would provide more information because the absorbance
measured would be proportional to the amount of antigen in the
wells.
Answer: It would provide more information because the absorbance
measured would be proportional to the amount of antigen in the
wells.
◉ Which is the correct term for a visible antigen-antibody complex?
Answers:
epitope
heavy chain complex
hybridoma
precipitin
Answer: preciptin
, ◉ Which technique could be used to rapidly diagnose strep throat or
mycoplasma pneumonia by labeling bacteria with fluorescent
monoclonal antibodies?
Answers:
brightfield microscopy and ELISA techniques
fluorescence microscopy and direct fluorescent antibody techniques
immunohistochemistry and immunostaining techniques in varying
combinations
western blotting with chromogens or fluorogens
Answer: fluorescence microscopy and direct fluorescent antibody
techniques
◉ What problem makes it difficult to use humanized monoclonal
antibody cocktails to treat pathogens?
Answers:
It is less expensive to use monoclonal antibody cocktails rather than
purified monoclonal antibodies.
It is too technically difficult to separate out the different monoclonal
antibodies.
Monoclonal antibodies are not sufficiently strong to target
pathogens without being used in high concentrations.
Monoclonal antibodies are so specific that they may not target all
serovars of a pathogen.
GUIDE TEST PAPER QUESTIONS AND
SOLUTIONS 2026
◉ A typical home pregnancy test is a lateral flow test that detects
human chorionic gonadotrophin in urine.
Answers:
True
False
Answer: true
◉ CD8 cells can be detected in host tissue by using immunostaining.
Answers:
True
False
Answer: true
◉ Double immunodiffusion is also known as which of the following?
Answers:
flocculation assay
Ouchterlony assay
,precipitin ring test
radial immunodiffusion assay
Answer: Ouchterlony assay
◉ Test sensitivity is defined as which of the following?
Answers:
the probability that an individual will have a false-positive test result
the probability that an individual with an infection will test positive
the probability that an individual with an infection will test negative
the probability that a test will detect multiple antigens
simultaneously
Answer: the probability that an individual with an infection will test
positive
◉ Lateral flow tests are inexpensive and easy to perform, which has
enabled the development of a wide range of diagnostic tests for
home use based upon this technology.
Answers:
True
False
Answer: true
,◉ Why would a spectrophotometer be helpful in interpreting the
results of a sandwich ELISA?
Answers:
It would allow for visualization of the antibody-antigen complex.
It would allow one to use a single test to differentiate previous
exposure from acute infection.
It would be faster, although less sensitive.
It would provide more information because the absorbance
measured would be proportional to the amount of antigen in the
wells.
Answer: It would provide more information because the absorbance
measured would be proportional to the amount of antigen in the
wells.
◉ Which is the correct term for a visible antigen-antibody complex?
Answers:
epitope
heavy chain complex
hybridoma
precipitin
Answer: preciptin
, ◉ Which technique could be used to rapidly diagnose strep throat or
mycoplasma pneumonia by labeling bacteria with fluorescent
monoclonal antibodies?
Answers:
brightfield microscopy and ELISA techniques
fluorescence microscopy and direct fluorescent antibody techniques
immunohistochemistry and immunostaining techniques in varying
combinations
western blotting with chromogens or fluorogens
Answer: fluorescence microscopy and direct fluorescent antibody
techniques
◉ What problem makes it difficult to use humanized monoclonal
antibody cocktails to treat pathogens?
Answers:
It is less expensive to use monoclonal antibody cocktails rather than
purified monoclonal antibodies.
It is too technically difficult to separate out the different monoclonal
antibodies.
Monoclonal antibodies are not sufficiently strong to target
pathogens without being used in high concentrations.
Monoclonal antibodies are so specific that they may not target all
serovars of a pathogen.
