Kaplan Nursing School Entrance Exams
Prep 8th Edition by Kaplan Nursing:
Latest KNAT Practice Questions and
Detailed Rationales for 2025/2026 ---
---
### Section 1: Reading Comprehension (Questions 1-30)
**Passage A (Questions 1-4)**
The human circulatory system is a closed system consisting of the
heart, blood vessels, and blood. The heart acts as a pump, creating
pressure that pushes blood through arteries, arterioles, and capillaries
,before returning via venules and veins. Oxygenated blood leaves the
left ventricle through the aorta, while deoxygenated blood returns to
the right atrium via the superior and inferior vena cava.
**Q1. Which of the following best describes the circulatory system
according to the passage?**
A) An open system with multiple pumps
B) A closed system with the heart as a pump
C) A system that only transports oxygen
D) A system that begins at the capillaries
**Correct Answer: B**
**Rationale:** The passage explicitly states the circulatory system is "a
closed system...with the heart acting as a pump."
**Q2. Where does oxygenated blood leave the heart?**
A) Right atrium
B) Right ventricle
C) Left ventricle
D) Left atrium
**Correct Answer: C**
,**Rationale:** The passage states, "Oxygenated blood leaves the left
ventricle through the aorta."
**Passage B (Questions 3-4)**
Chronic kidney disease (CKD) affects approximately 15% of U.S. adults.
Early stages often present no symptoms, making screening critical for
at-risk populations including those with diabetes, hypertension, or
family history. Progression can be slowed with ACE inhibitors, blood
pressure control, and dietary modifications including reduced sodium
and protein intake.
**Q3. According to the passage, which population should be screened
for CKD?**
A) All adults over age 50
B) Those with diabetes or hypertension
C) Individuals with a history of pneumonia
D) Athletes and active adults
**Correct Answer: B**
**Rationale:** The passage specifically mentions "at-risk populations
including those with diabetes, hypertension, or family history."
**Q4. Which intervention is NOT mentioned for slowing CKD
progression?**
A) ACE inhibitors
, B) Increased protein intake
C) Blood pressure control
D) Reduced sodium intake
**Correct Answer: B**
**Rationale:** The passage states "reduced sodium and protein
intake," not increased protein.
**Questions 5-8 refer to the following passage:**
**Passage C: The Role of the Liver**
The liver is a vital organ located in the upper right quadrant of the
abdomen. It performs over 500 functions, including the production of
bile to aid in fat digestion, the conversion of excess glucose into
glycogen for storage, and the detoxification of harmful substances like
ammonia (converting it to urea). Additionally, the liver synthesizes
proteins necessary for blood plasma and regulates blood clotting.
**Q5. Based on the passage, what happens to excess glucose in the
body?**
A) It is converted into protein.
B) It is immediately excreted by the kidneys.
C) It is converted into glycogen for storage.
D) It is used to produce bile.
Prep 8th Edition by Kaplan Nursing:
Latest KNAT Practice Questions and
Detailed Rationales for 2025/2026 ---
---
### Section 1: Reading Comprehension (Questions 1-30)
**Passage A (Questions 1-4)**
The human circulatory system is a closed system consisting of the
heart, blood vessels, and blood. The heart acts as a pump, creating
pressure that pushes blood through arteries, arterioles, and capillaries
,before returning via venules and veins. Oxygenated blood leaves the
left ventricle through the aorta, while deoxygenated blood returns to
the right atrium via the superior and inferior vena cava.
**Q1. Which of the following best describes the circulatory system
according to the passage?**
A) An open system with multiple pumps
B) A closed system with the heart as a pump
C) A system that only transports oxygen
D) A system that begins at the capillaries
**Correct Answer: B**
**Rationale:** The passage explicitly states the circulatory system is "a
closed system...with the heart acting as a pump."
**Q2. Where does oxygenated blood leave the heart?**
A) Right atrium
B) Right ventricle
C) Left ventricle
D) Left atrium
**Correct Answer: C**
,**Rationale:** The passage states, "Oxygenated blood leaves the left
ventricle through the aorta."
**Passage B (Questions 3-4)**
Chronic kidney disease (CKD) affects approximately 15% of U.S. adults.
Early stages often present no symptoms, making screening critical for
at-risk populations including those with diabetes, hypertension, or
family history. Progression can be slowed with ACE inhibitors, blood
pressure control, and dietary modifications including reduced sodium
and protein intake.
**Q3. According to the passage, which population should be screened
for CKD?**
A) All adults over age 50
B) Those with diabetes or hypertension
C) Individuals with a history of pneumonia
D) Athletes and active adults
**Correct Answer: B**
**Rationale:** The passage specifically mentions "at-risk populations
including those with diabetes, hypertension, or family history."
**Q4. Which intervention is NOT mentioned for slowing CKD
progression?**
A) ACE inhibitors
, B) Increased protein intake
C) Blood pressure control
D) Reduced sodium intake
**Correct Answer: B**
**Rationale:** The passage states "reduced sodium and protein
intake," not increased protein.
**Questions 5-8 refer to the following passage:**
**Passage C: The Role of the Liver**
The liver is a vital organ located in the upper right quadrant of the
abdomen. It performs over 500 functions, including the production of
bile to aid in fat digestion, the conversion of excess glucose into
glycogen for storage, and the detoxification of harmful substances like
ammonia (converting it to urea). Additionally, the liver synthesizes
proteins necessary for blood plasma and regulates blood clotting.
**Q5. Based on the passage, what happens to excess glucose in the
body?**
A) It is converted into protein.
B) It is immediately excreted by the kidneys.
C) It is converted into glycogen for storage.
D) It is used to produce bile.
