SCRIPT 2026 FULL QUESTIONS AND
CORRECT ANSWERS GRADED A+
●● broad spectrum penicillins. Answer: - ampicillin and amoxicillin
- good oral absorption (amoxicillin = excellent)
- broad spectrum (improved against gram negative organisms - e.coli,
salmonella, shingella, H. Influenza, H pylori, proteus)
●● How do penicillins and cephalosporins work?. Answer: By
weakening the cell wall and promoting lysis and death
●● Bactericidal drugs are. Answer: Directly lethal to bacteria at
achievable concentrations
●● Why are narrow spectrum drugs preferred over broad spectrum
antibiotics?. Answer: Broad spectrum antibiotics do the most to facilitate
emergence of resistance
●● How does bacterial resistance develop with penicillins?. Answer: -
production of penicillin binding proteins that have low affinity for
penicillins
-inability of penicillins to reach their target
, -inactivation of penicillins by bacterial enzymes
●● Mary is a 20 year old female you have diagnosed him with strep
throat. She has had an anaphylactic reaction to penicillin. Which of the
following antibiotics is appropriate for Mary?. Answer: Azithromycin
●● What are penicillinases?. Answer: Beta-lactamases that act
selectively on penicillins
●● The following are Penicillinases-resistant penicillins. Answer:
Oxacillin, Dicloxacillin, Nafcillin
●● The following are broad spectrum penicillins (aminopenicillins).
Answer: Amoxicillin and ampicillin
●● The following are extended-spectrum penicillins (antipseudomonal).
Answer: Ticarcillin and Piperacillin
●● The following are beta-lactamase inhibitors. Answer: Sulbactam,
tazobactam and clavilanic acid
●● Which cephalosporins are rarely used for active infections?. Answer:
Second generation