FULL SOLUTION VIEW AHEAD QUESTIONS
AND ANSWERS GRADED A+
●● Main reason for abx resistance? Answer: inappropriate abx use
●● What is the reason for BL resistance? Answer: Modification of target
sites
●● There is a cross-sensitivity between PNC and ceps. due to a similar
___ _____ ring Answer: Beta-lactam
●● What meds require loading doses? (For sepsis, meningitis, PNA)
What are the doses? Answer: Vanc (25-30 mg/kg IV) based on BW
(usually roughly rounded to 250 mg), ahminoglycosides (Gent/tobra -
7mg/kg IV x 1), Amikacin ((15-20 mg/kg IV x 1), azithromycin )250 mg
PO daily on days 2-5).
●● Nitrofuritin caries a risk for ____ ________. Answer: Pulmonary
fibrosis
●● Amoxicillin caries a risk for diarrhea. What should be done about
this? Answer: Probiotics
, ●● Polymixins are ____ and _______-toxic. Answer: nephro and neuro
●● (TB) Replace INH with _________ with resistance. Answer:
Ethambutol
●● (TB) Monitor ____ with Ethambutol due to optic neuritis risk (vision
changes, loss of red-green color). Answer: vision.
●● (TB) What med is best for TB exposure? (first line) Answer: INH -
first line
●● (TB) Monitor for Ethambutol for ______ changes. Answer: Visual
●● (TB) INH (Isoniazid) comes with a risk of ________ and should be
treated with B__. Answer: Paresthesia; B6
●● (TB) __________ replaces streptomycin if resistant. Answer:
Kanamycin
●● (TB) Check what labs with streptomycin? Answer: Cr and BUN
●● A sputum test should be negative ___-___ months after therapy.
Answer: 2-3