Comprehensive General Biology Competency Assessment
Cellular Energy, Genetics & Molecular Biology
Academic Year 2026/2027
50 Multiple-Choice Questions
Undergraduate Biology Program
, Table of Contents
Exam Instructions ........................................ 3
Section I: Cellular Respiration & Energy Metabolism ........................................ 4
Section II: Photosynthesis & Light Energy Conversion ........................................ 6
Section III: Cell Division & Genetic Continuity ........................................ 8
Section IV: Mendelian Genetics & Inheritance Patterns ........................................ 10
Section V: DNA Structure, Replication & Gene Expression ........................................ 12
Section VI: Mutations & Genetic Variation ........................................ 14
Section VII: Scenario-Based Application ........................................ 16
Answer Key ........................................ 17
, Exam Instructions
Exam Structure: This examination consists of 50 multiple-choice questions (MCQ) distributed
across 7 domain sections covering Cellular Energy, Genetics, and Molecular Biology.
Timing: You have 75 minutes to complete this examination. Pace yourself at approximately 1.5
minutes per question.
Passing Score: A score of 75–80% (38–40 correct answers out of 50) is required to pass.
Question Types: This exam includes the following item types:
• Standard Multiple-Choice Questions (single best answer)
• Select-All-That-Apply (SATA) questions — select all correct options
• Pathway sequencing questions — order biological processes
• Genetic cross calculation questions — apply Punnett square reasoning
• Molecular mechanism identification — determine enzyme/protein function
• Experimental design interpretation — analyze data and draw conclusions
Important Notes:
• Read each question carefully before selecting your answer.
• For SATA questions, more than one option may be correct. Select ALL that apply.
• There is no penalty for guessing; answer every question.
• Mark your answers on the provided answer sheet.
• You may NOT use any electronic devices during the exam.
Section I: Cellular Respiration & Energy Metabolism
This section covers glycolysis, pyruvate oxidation, the citric acid cycle, the electron transport chain,
chemiosmosis, and anaerobic fermentation pathways. Questions assess understanding of ATP
yields, enzyme functions, and metabolic regulation.
Q1. During glycolysis, glucose is split into two molecules of pyruvate. What is the net
ATP yield per glucose molecule during this cytoplasmic pathway?
A. 0 ATP (all ATP produced is consumed in the investment phase)
B. 2 ATP (4 produced minus 2 consumed in the investment phase)
C. 4 ATP (gross yield with no consumption)
D. 36 ATP (total aerobic yield from one glucose)
Correct Answer: B. 2 ATP (4 produced minus 2 consumed in the investment phase)