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INTRO TO PHARM TEST / ACTUAL TEST
2025/2026 INTRO TO PHARMACOLOGY
ACCURATE TEST COMPLETE REAL
QUESTIONS AND CORRECT DETAILED
ANSWERS (100% CORRECT VERIFIED
SOLUTIONS) LATEST UPDATED VERSION
|GUARANTEED PASS.
1. A nurse is teaching a patient about drug names. Which
statement indicates understanding?
A) “The generic name is the brand name given by the
manufacturer.”
B) “The trade name is always the same regardless of the
manufacturer.”
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C) “The generic name is the official non-proprietary name
listed in the USP.”
D) “Trade names are chemically simpler than generic names.”
Answer: C – The generic name (e.g., acetaminophen) is
official. Trade names (Tylenol) vary by manufacturer.
2. What does “pharmacokinetics” mean?
A) Study of how drugs change the body’s function
B) Study of what the body does to the drug
C) The drug’s highest concentration in the blood
D) The process of prescribing medications
Answer: B – Pharmacokinetics = absorption, distribution,
metabolism, excretion.
3. (Scenario) A drug is 95% protein-bound. A second drug
that also binds to albumin is administered. What is the risk?
A) Increased excretion of first drug
B) Decreased metabolism of first drug
C) Increased free fraction of first drug → toxicity
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D) Complete inactivation of both drugs
Answer: C – Displacement increases free (active) drug.
4. (Select all that apply) Which routes undergo first-pass
metabolism?
A) Sublingual
B) Oral
C) Intravenous
D) Rectal (partially)
E) Intramuscular
Answer: B, D – Oral: high first-pass; rectal: partial; others
bypass liver initially.
5. Half-life = 4 hours. Time to reach steady state?
A) 8 h
B) 12 h
C) 20 h
D) 24 h
Answer: C – 5 half-lives = 20 hours.
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6. Which phase involves conjugation (glucuronidation)?
A) Phase I (oxidation)
B) Phase II (synthetic)
C) Phase 0 (dissolution)
D) Absorption phase
Answer: B – Phase II makes drugs water-soluble.
7. (Scenario) Patient with cirrhosis receives a drug
metabolized by the liver. Expected outcome?
A) Reduced half-life
B) Increased accumulation and toxicity
C) Faster clearance
D) No change
Answer: B – Impaired metabolism → higher levels.
8. Therapeutic index (TI) formula:
A) TD50/ED50
B) ED50/TD50
C) LD50/ED50
INTRO TO PHARM TEST / ACTUAL TEST
2025/2026 INTRO TO PHARMACOLOGY
ACCURATE TEST COMPLETE REAL
QUESTIONS AND CORRECT DETAILED
ANSWERS (100% CORRECT VERIFIED
SOLUTIONS) LATEST UPDATED VERSION
|GUARANTEED PASS.
1. A nurse is teaching a patient about drug names. Which
statement indicates understanding?
A) “The generic name is the brand name given by the
manufacturer.”
B) “The trade name is always the same regardless of the
manufacturer.”
,Page 2 of 137
C) “The generic name is the official non-proprietary name
listed in the USP.”
D) “Trade names are chemically simpler than generic names.”
Answer: C – The generic name (e.g., acetaminophen) is
official. Trade names (Tylenol) vary by manufacturer.
2. What does “pharmacokinetics” mean?
A) Study of how drugs change the body’s function
B) Study of what the body does to the drug
C) The drug’s highest concentration in the blood
D) The process of prescribing medications
Answer: B – Pharmacokinetics = absorption, distribution,
metabolism, excretion.
3. (Scenario) A drug is 95% protein-bound. A second drug
that also binds to albumin is administered. What is the risk?
A) Increased excretion of first drug
B) Decreased metabolism of first drug
C) Increased free fraction of first drug → toxicity
,Page 3 of 137
D) Complete inactivation of both drugs
Answer: C – Displacement increases free (active) drug.
4. (Select all that apply) Which routes undergo first-pass
metabolism?
A) Sublingual
B) Oral
C) Intravenous
D) Rectal (partially)
E) Intramuscular
Answer: B, D – Oral: high first-pass; rectal: partial; others
bypass liver initially.
5. Half-life = 4 hours. Time to reach steady state?
A) 8 h
B) 12 h
C) 20 h
D) 24 h
Answer: C – 5 half-lives = 20 hours.
, Page 4 of 137
6. Which phase involves conjugation (glucuronidation)?
A) Phase I (oxidation)
B) Phase II (synthetic)
C) Phase 0 (dissolution)
D) Absorption phase
Answer: B – Phase II makes drugs water-soluble.
7. (Scenario) Patient with cirrhosis receives a drug
metabolized by the liver. Expected outcome?
A) Reduced half-life
B) Increased accumulation and toxicity
C) Faster clearance
D) No change
Answer: B – Impaired metabolism → higher levels.
8. Therapeutic index (TI) formula:
A) TD50/ED50
B) ED50/TD50
C) LD50/ED50
