Page 1 of 197
LATEST PSI COS EXAM / PSI COS ACTUAL
EXAM 2025/2026 AND A STUDY GUIDE
TEST QUESTIONS COMPLETE ACCURATE
TEST REAL QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) A
NEW UPDATED VERSIONS |ASSURED
SUCCESS A+
Q1. What is the highest level of decontamination that kills
all microorganisms, including bacterial spores?
A. Sanitation
B. Disinfection
,Page 2 of 197
C. Sterilization
D. Antisepsis
Answer: C. Sterilization
Rationale: Sterilization destroys all microbial life including
bacterial spores, typically achieved through an autoclave.
Disinfection kills most but not spores. Sanitation reduces
microbial load but does not eliminate pathogens.
Q2. According to OSHA, which disinfectant is effective
against bloodborne pathogens such as Hepatitis B and HIV?
A. Quaternary ammonium compounds (Quats)
B. Isopropyl alcohol 70%
C. An EPA-registered hospital disinfectant with tuberculocidal
claim
D. Hydrogen peroxide 3%
Answer: C. An EPA-registered hospital disinfectant with
tuberculocidal claim
,Page 3 of 197
Rationale: Only disinfectants labeled tuberculocidal are
considered high-level disinfectants effective against
bloodborne pathogens. Quats are low-level disinfectants
ineffective against HBV/HIV.
Q3. Why do tuberculocidal disinfectants require special
handling?
A. They have a low pH
B. They require a special method of disposal
C. They must be heated before use
D. They are ineffective if frozen
Answer: B. They require a special method of disposal
Rationale: Tuberculocidal disinfectants are often toxic or
hazardous waste, requiring specific disposal methods per
EPA/OSHA guidelines to protect environmental and human
health.
, Page 4 of 197
Q4. Which is the FIRST step if you get blood or other
potentially infectious materials in your eyes?
A. Call 911
B. Immediately flood the exposed area with water
C. Wipe the eye with a dry tissue
D. Apply alcohol to the eye
Answer: B. Immediately flood the exposed area with water
Rationale: In an exposure incident, the affected area must be
flushed with water immediately to dilute and remove the
pathogen before seeking medical evaluation.
Q5. Which company certifies the safety of pedicure chairs
and hair dryers?
A. FDA
B. OSHA
C. Underwriters Laboratories (UL)
D. EPA
LATEST PSI COS EXAM / PSI COS ACTUAL
EXAM 2025/2026 AND A STUDY GUIDE
TEST QUESTIONS COMPLETE ACCURATE
TEST REAL QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) A
NEW UPDATED VERSIONS |ASSURED
SUCCESS A+
Q1. What is the highest level of decontamination that kills
all microorganisms, including bacterial spores?
A. Sanitation
B. Disinfection
,Page 2 of 197
C. Sterilization
D. Antisepsis
Answer: C. Sterilization
Rationale: Sterilization destroys all microbial life including
bacterial spores, typically achieved through an autoclave.
Disinfection kills most but not spores. Sanitation reduces
microbial load but does not eliminate pathogens.
Q2. According to OSHA, which disinfectant is effective
against bloodborne pathogens such as Hepatitis B and HIV?
A. Quaternary ammonium compounds (Quats)
B. Isopropyl alcohol 70%
C. An EPA-registered hospital disinfectant with tuberculocidal
claim
D. Hydrogen peroxide 3%
Answer: C. An EPA-registered hospital disinfectant with
tuberculocidal claim
,Page 3 of 197
Rationale: Only disinfectants labeled tuberculocidal are
considered high-level disinfectants effective against
bloodborne pathogens. Quats are low-level disinfectants
ineffective against HBV/HIV.
Q3. Why do tuberculocidal disinfectants require special
handling?
A. They have a low pH
B. They require a special method of disposal
C. They must be heated before use
D. They are ineffective if frozen
Answer: B. They require a special method of disposal
Rationale: Tuberculocidal disinfectants are often toxic or
hazardous waste, requiring specific disposal methods per
EPA/OSHA guidelines to protect environmental and human
health.
, Page 4 of 197
Q4. Which is the FIRST step if you get blood or other
potentially infectious materials in your eyes?
A. Call 911
B. Immediately flood the exposed area with water
C. Wipe the eye with a dry tissue
D. Apply alcohol to the eye
Answer: B. Immediately flood the exposed area with water
Rationale: In an exposure incident, the affected area must be
flushed with water immediately to dilute and remove the
pathogen before seeking medical evaluation.
Q5. Which company certifies the safety of pedicure chairs
and hair dryers?
A. FDA
B. OSHA
C. Underwriters Laboratories (UL)
D. EPA
