Page 1 of 180
NEWEST CTCD EXAM 2026/2027
AND A NEW UPDATED STUDY GUIDE
COMPLETE 300 ACCURATE QUESTIONS
AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) LATEST
UPDATED VERSIONS|ALREADY GRADED
A+ (BRAND NEW!) CTCD ACTUAL EXAM
,Page 2 of 180
1. A potential donor’s medical history reveals a diagnosis of
Creutzfeldt-Jakob Disease (CJD) 4 years ago. What is the
appropriate action?
A) Accept the donor after a 5-year waiting period.
B) Accept the donor if only dura mater was transplanted.
C) Permanently defer the donor.
D) Accept only musculoskeletal tissues, not ocular.
Answer: C
Rationale: AATB standards mandate permanent deferral for
diagnosed CJD or any known risk factor. No test exists for CJD
in banked tissue, and prions resist sterilization.
2. Next-of-kin states the donor received human pituitary-
derived growth hormone in 1985. You should: A) Accept
the donor for all tissues.
B) Defer the donor due to risk of CJD.
C) Accept only skin grafts.
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D) Require a brain biopsy prior to recovery.
Answer: B
*Rationale: Pituitary-derived growth hormone (used before
synthetic versions in 1985) is a known vector for iatrogenic
CJD. Indefinite deferral per CDC/AATB.*
3. Which condition is an absolute contraindication for any tissue
donation?
A) Treated syphilis 10 years ago.
B) Hepatitis B core antibody positive with negative surface
antigen.
C) Systemic sepsis of unknown origin at time of death.
D) History of gout.
Answer: C
*Rationale: Active systemic sepsis at death indicates high
bacterial contamination risk. Gout is not a contraindication.
Treated syphilis with cure >12 months acceptable. Isolated
, Page 4 of 180
HBcAb+ may be accepted after risk review.*
4. A 55-year-old male died of stroke. History: IV drug use 30
years ago. Serologies negative. Can he be accepted? A) Yes,
because serologies are negative.
B) Yes, if medical director approves based on risk/benefit.
C) No, IV drug use is a permanent deferral regardless of
time.
D) No, because of age.
Answer: B
Rationale: AATB allows risk review for historical behaviors (e.g.,
IV drug use >5 years ago with negative serologies) by the
blood bank medical director. This is a non-mandatory deferral.
5. Scenario: 32-year-old donor died from blunt head trauma.
NOK interview: tattoo in a licensed parlor 8 months ago; root
canal 2 weeks before death (asymptomatic). What is
required?
NEWEST CTCD EXAM 2026/2027
AND A NEW UPDATED STUDY GUIDE
COMPLETE 300 ACCURATE QUESTIONS
AND CORRECT DETAILED ANSWERS WITH
RATIONALES (VERIFIED ANSWERS) LATEST
UPDATED VERSIONS|ALREADY GRADED
A+ (BRAND NEW!) CTCD ACTUAL EXAM
,Page 2 of 180
1. A potential donor’s medical history reveals a diagnosis of
Creutzfeldt-Jakob Disease (CJD) 4 years ago. What is the
appropriate action?
A) Accept the donor after a 5-year waiting period.
B) Accept the donor if only dura mater was transplanted.
C) Permanently defer the donor.
D) Accept only musculoskeletal tissues, not ocular.
Answer: C
Rationale: AATB standards mandate permanent deferral for
diagnosed CJD or any known risk factor. No test exists for CJD
in banked tissue, and prions resist sterilization.
2. Next-of-kin states the donor received human pituitary-
derived growth hormone in 1985. You should: A) Accept
the donor for all tissues.
B) Defer the donor due to risk of CJD.
C) Accept only skin grafts.
,Page 3 of 180
D) Require a brain biopsy prior to recovery.
Answer: B
*Rationale: Pituitary-derived growth hormone (used before
synthetic versions in 1985) is a known vector for iatrogenic
CJD. Indefinite deferral per CDC/AATB.*
3. Which condition is an absolute contraindication for any tissue
donation?
A) Treated syphilis 10 years ago.
B) Hepatitis B core antibody positive with negative surface
antigen.
C) Systemic sepsis of unknown origin at time of death.
D) History of gout.
Answer: C
*Rationale: Active systemic sepsis at death indicates high
bacterial contamination risk. Gout is not a contraindication.
Treated syphilis with cure >12 months acceptable. Isolated
, Page 4 of 180
HBcAb+ may be accepted after risk review.*
4. A 55-year-old male died of stroke. History: IV drug use 30
years ago. Serologies negative. Can he be accepted? A) Yes,
because serologies are negative.
B) Yes, if medical director approves based on risk/benefit.
C) No, IV drug use is a permanent deferral regardless of
time.
D) No, because of age.
Answer: B
Rationale: AATB allows risk review for historical behaviors (e.g.,
IV drug use >5 years ago with negative serologies) by the
blood bank medical director. This is a non-mandatory deferral.
5. Scenario: 32-year-old donor died from blunt head trauma.
NOK interview: tattoo in a licensed parlor 8 months ago; root
canal 2 weeks before death (asymptomatic). What is
required?
