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2026 HESI RN Exit Exam | Versions 1-10 | 386 NGN-Style Questions & Rationales | Already Graded A+

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Pass the 2026 HESI RN Exit Exam with confidence using this comprehensive test bank featuring 386 exam-style questions and detailed rationales. This study guide includes ten complete versions (V1-V10) of the HESI RN Exit Exam, covering all core nursing content areas required for nursing school graduation and NCLEX-RN success. Each question is verified and includes a detailed explanation to reinforce key concepts and clinical judgment. Topics covered include: Medical-Surgical Nursing: Heart failure, COPD, pneumonia, asthma, diabetes (DKA, HHS), pancreatitis, cirrhosis, acute kidney injury, stroke, seizures, meningitis, HIV, cancer Critical Care & Emergency: ARDS, mechanical ventilation (plateau pressure, PEEP, lung-protective ventilation), sepsis/septic shock, vasopressors (norepinephrine, dobutamine), ICP monitoring, Cushing's triad, autonomic dysreflexia, compartment syndrome, pulmonary embolism, DVT Pharmacology: Heparin (aPTT monitoring, HIT, protamine), warfarin (INR, vitamin K), insulin (DKA management, potassium shifts), metformin (lactic acidosis, contrast precautions), digoxin toxicity, furosemide (hypokalemia, ototoxicity), vancomycin (trough levels, red man syndrome), aminoglycosides (nephrotoxicity), thrombolytics (tPA), narcotics/naloxone, benzodiazepines/flumazenil, anaphylaxis (epinephrine) Fluid & Electrolytes: Hyponatremia (SIADH), hyperkalemia (ECG changes, calcium gluconate, insulin/dextrose), hypokalemia, dehydration, fluid resuscitation, blood transfusion reactions (hemolytic, febrile, allergic, TRALI, TACO) Cardiovascular: Atrial fibrillation, warfarin, amiodarone interaction, MI (STEMI, aspirin), hypertension, heart failure (HFrEF, ACE inhibitors, beta-blockers, spironolactone, furosemide), pulmonary edema, LVAD Neurology: Ischemic stroke (tPA criteria, aspirin), increased ICP (mannitol, HOB elevation), meningitis (Kernig/Brudzinski), seizure disorders, Parkinson's disease Renal & Endocrine: CKD (dietary restrictions, erythropoietin, phosphate binders), AKI, hemodialysis, DKA vs. HHS, thyroid disorders, adrenal insufficiency Gastrointestinal: Pancreatitis (amylase/lipase, hypocalcemia, Cullen/Grey Turner sign), cirrhosis (ascites, spironolactone, lactulose, paracentesis, variceal bleeding, octreotide), cholecystitis, NG tube management, enteral nutrition Infectious Disease: Sepsis (SIRS, qSOFA, fluid resuscitation, antibiotics), pneumonia, UTI, cellulitis, C. diff, TB, HIV Hematology & Oncology: Blood transfusion (compatibility, reactions), DIC, HIT, chemotherapy complications (febrile neutropenia), thrombocytopenia, anemia Psychiatric/Mental Health: Bipolar disorder (lithium toxicity, mania), schizophrenia (antipsychotics, EPS, clozapine), depression (MAOIs, SSRIs), opioid use disorder (methadone, buprenorphine, naloxone) Perioperative & Postoperative Care: Preoperative assessment (metformin, anticoagulation), postoperative complications (atelectasis, DVT, PE, ileus), pain management (PCA, opioids), wound care Patient Education & Discharge Planning: Low-sodium diet, warfarin teaching, colostomy care, insulin administration, fall prevention, home safety Perfect for nursing students preparing for the HESI Exit Exam, NCLEX-RN, or course finals. Includes answers with rationales for self-assessment and clinical reasoning development.

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Voorbeeld van de inhoud

2026 HESI RN Exit V1-V10 Actual Exams |
NGN-Style Questions | HESI Exit Nursing (PDF),
2026 Exam · 386 Questions · With Rationales




ati.
2026 HESI RN Exit V1-V10 Actual Exams | NGN-Style Questions | HESI Exit Nursing (PDF), Exams of Nursing


Question: 1 of 386

A patient with a history of heart failure and chronic obstructive pulmonary disease is admitted with acute
dyspnea. The nurse notes jugular venous distention, bilateral crackles, and an SpO2 of 88% on room air.

A. Administer intravenous furosemide 40 mg

B. Place the patient in high Fowler's position

C. Obtain a stat arterial blood gas

D. Apply non-rebreather mask at 15 L/min




PREVIOUS CONTINUE



A patient with a history of heart failure and chronic obstructive pulmonary disease is
admitted with acute dyspnea. The nurse notes jugular venous distention, bilateral
crackles, and an SpO2 of 88% on room air. Which intervention should the nurse
implement first?



A. Administer intravenous furosemide 40 mg



' B. Place the patient in high Fowler's position



C. Obtain a stat arterial blood gas



D. Apply non-rebreather mask at 15 L/min


Correct Answer: B

High Fowler's position maximizes chest expansion and improves oxygenation, addressing the immediate threat
of hypoxia. While oxygen and diuretics are important, positioning is the quickest noninvasive action to enhance
ventilation. ABG is diagnostic, not therapeutic.




Page 1 | 2026 HESI RN Exit V1-V10 Actual Exams | NGN-Style Questions | HESI Exit Nursing (PDF), Exams of Nursing 2026

, 2026 HESI RN Exit V1-V10 Actual Exams |
NGN-Style Questions | HESI Exit Nursing (PDF),
2026 Exam · 386 Questions · With Rationales




ati.
2026 HESI RN Exit V1-V10 Actual Exams | NGN-Style Questions | HESI Exit Nursing (PDF), Exams of Nursing


Question: 2 of 386

A patient receiving a continuous heparin infusion has an aPTT of 120 seconds (therapeutic range 60-80
seconds). The nurse notes coffee-ground emesis and a drop in blood pressure from 128/78 to 94/52 mm Hg.

A. Administer vitamin K intramuscularly

B. Stop the heparin infusion and administer protamine sulfate

C. Increase the infusion rate to achieve therapeutic aPTT

D. Draw aPTT and PT/INR and notify the healthcare provider




PREVIOUS CONTINUE



A patient receiving a continuous heparin infusion has an aPTT of 120 seconds
(therapeutic range 60-80 seconds). The nurse notes coffee-ground emesis and a drop in
blood pressure from 128/78 to 94/52 mm Hg. What should the nurse do first?



A. Administer vitamin K intramuscularly



' B. Stop the heparin infusion and administer protamine sulfate



C. Increase the infusion rate to achieve therapeutic aPTT



D. Draw aPTT and PT/INR and notify the healthcare provider


Correct Answer: B

The patient exhibits signs of heparin overdose with bleeding (coffee-ground emesis, hypotension). The
immediate priority is to stop the infusion and reverse anticoagulation with protamine sulfate. Vitamin K reverses
warfarin, not heparin. Delaying action could worsen hemorrhage.




Page 2 | 2026 HESI RN Exit V1-V10 Actual Exams | NGN-Style Questions | HESI Exit Nursing (PDF), Exams of Nursing 2026

, 2026 HESI RN Exit V1-V10 Actual Exams |
NGN-Style Questions | HESI Exit Nursing (PDF),
2026 Exam · 386 Questions · With Rationales




ati.
2026 HESI RN Exit V1-V10 Actual Exams | NGN-Style Questions | HESI Exit Nursing (PDF), Exams of Nursing


Question: 3 of 386

Which of the following assessment findings is most indicative of a patient experiencing neuroleptic malignant
syndrome (NMS) rather than serotonin syndrome?

A. Hyperreflexia and clonus

B. Diaphoresis and flushing

C. Lead-pipe rigidity and bradyreflexia

D. Tachycardia and hypertension




PREVIOUS CONTINUE



Which of the following assessment findings is most indicative of a patient experiencing
neuroleptic malignant syndrome (NMS) rather than serotonin syndrome?



A. Hyperreflexia and clonus



B. Diaphoresis and flushing



' C. Lead-pipe rigidity and bradyreflexia



D. Tachycardia and hypertension


Correct Answer: C

NMS is characterized by 'lead-pipe' muscle rigidity, bradyreflexia, and autonomic instability, whereas serotonin
syndrome presents with hyperreflexia, clonus, and tremor. Both may have autonomic changes, but rigidity and
bradyreflexia are hallmark of NMS.




Page 3 | 2026 HESI RN Exit V1-V10 Actual Exams | NGN-Style Questions | HESI Exit Nursing (PDF), Exams of Nursing 2026

, 2026 HESI RN Exit V1-V10 Actual Exams |
NGN-Style Questions | HESI Exit Nursing (PDF),
2026 Exam · 386 Questions · With Rationales




ati.
2026 HESI RN Exit V1-V10 Actual Exams | NGN-Style Questions | HESI Exit Nursing (PDF), Exams of Nursing


Question: 4 of 386

A patient with end-stage renal disease is scheduled for hemodialysis. The nurse reviews the medication
administration record. Which medication should be withheld prior to dialysis?

A. Erythropoietin alfa 10,000 units subcutaneously

B. Sevelamer carbonate 800 mg orally

C. Enalapril 10 mg orally

D. Calcitriol 0.5 mcg intravenously




PREVIOUS CONTINUE



A patient with end-stage renal disease is scheduled for hemodialysis. The nurse reviews
the medication administration record. Which medication should be withheld prior to
dialysis?



A. Erythropoietin alfa 10,000 units subcutaneously



B. Sevelamer carbonate 800 mg orally



' C. Enalapril 10 mg orally



D. Calcitriol 0.5 mcg intravenously


Correct Answer: C

ACE inhibitors like enalapril can cause hypotension during dialysis due to reduced angiotensin II. They are
often held on dialysis days. Erythropoietin, sevelamer, and calcitriol are typically given per schedule and do not
pose acute risk during dialysis.




Page 4 | 2026 HESI RN Exit V1-V10 Actual Exams | NGN-Style Questions | HESI Exit Nursing (PDF), Exams of Nursing 2026

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