Molecular Biology (BIOL 4320) Exam 2
TTU Questions & Answers (Grade A+)
What is the organization of replication forks? -
correct answer ✅Semi trombone structure
How are replication factories generated? -
correct answer ✅Covalently associated helicases
Is a mutation in a terminus fatal in prokaryotes? -
correct answer ✅No, they only increase efficiency
What is the goal of a primer? -
correct answer ✅Create a free 3'-OH end to allow DNA
polymerase to function
What is a replicon? -
correct answer ✅Unit of genome where DNA is replicated
Each replicon has at least 1 ___? -
correct answer ✅Origin of replication
How many origins of replication do eukaryotes have? -
correct answer ✅Multiple
, Molecular Biology (BIOL 4320) Exam 2
TTU Questions & Answers (Grade A+)
What removes primers? -
correct answer ✅Rnase H
What does Rnase H recognize? -
correct answer ✅RNA DNA hybrid
What is left after Rnase H action? -
correct answer ✅A gap, which is filled by DNA polymerase
When is replication bidirectional? -
correct answer ✅When 2 replication forks are created at an origin
How does the movement of polymerases differ in leading vs.
lagging strand synthesis? -
correct answer ✅Polymerase chases the replication fork in leading
strand synthesis. Polymerase move in direction opposite of
replication fork in lagging strand synthesis.
What is the direction of growth of the lagging strand in DNA
synthesis? -
correct answer ✅3' to 5'
TTU Questions & Answers (Grade A+)
What is the organization of replication forks? -
correct answer ✅Semi trombone structure
How are replication factories generated? -
correct answer ✅Covalently associated helicases
Is a mutation in a terminus fatal in prokaryotes? -
correct answer ✅No, they only increase efficiency
What is the goal of a primer? -
correct answer ✅Create a free 3'-OH end to allow DNA
polymerase to function
What is a replicon? -
correct answer ✅Unit of genome where DNA is replicated
Each replicon has at least 1 ___? -
correct answer ✅Origin of replication
How many origins of replication do eukaryotes have? -
correct answer ✅Multiple
, Molecular Biology (BIOL 4320) Exam 2
TTU Questions & Answers (Grade A+)
What removes primers? -
correct answer ✅Rnase H
What does Rnase H recognize? -
correct answer ✅RNA DNA hybrid
What is left after Rnase H action? -
correct answer ✅A gap, which is filled by DNA polymerase
When is replication bidirectional? -
correct answer ✅When 2 replication forks are created at an origin
How does the movement of polymerases differ in leading vs.
lagging strand synthesis? -
correct answer ✅Polymerase chases the replication fork in leading
strand synthesis. Polymerase move in direction opposite of
replication fork in lagging strand synthesis.
What is the direction of growth of the lagging strand in DNA
synthesis? -
correct answer ✅3' to 5'
