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EPALS Pediatric Advanced Life Support Exam 2026 | 500+ Exam Questions & Correct Answers | Airway Management, Resuscitation, Trauma, DKA & Pediatric Emergencies | Advanced Pediatric Emergency Medicine

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This comprehensive EPALS Pediatric Advanced Life Support Exam Study Guide for 2026 contains more than 500 verified exam questions and detailed answers covering advanced pediatric emergency medicine, pediatric resuscitation science, airway management, trauma stabilization, neonatal life support, cardiac emergencies, respiratory failure, electrolyte disturbances, shock management, and critical care pharmacology. The material provides extensive review content on Poiseuille’s Law, pediatric airway anatomy, bronchiolitis, croup, epiglottitis, asthma exacerbations, anaphylaxis, diabetic ketoacidosis (DKA), cardiac arrest algorithms, arrhythmia management, mechanical ventilation, trauma protocols, burns management, fluid resuscitation, electrolyte abnormalities, pediatric advanced airway procedures, and neonatal resuscitation guidelines. This study guide is highly relevant for pediatric intensive care unit (PICU) nurses, emergency department clinicians, pediatric nursing students, advanced pediatric life support trainees, paramedic students, pediatric residents, neonatal intensive care unit (NICU) staff, respiratory therapists, emergency medicine physicians, pediatric anesthetic trainees, acute care practitioners, and healthcare professionals preparing for EPALS, PALS, pediatric emergency medicine, critical care, or advanced resuscitation certification examinations. The content aligns closely with evidence-based clinical frameworks published by the Resuscitation Council UK (RCUK), European Resuscitation Council (ERC), Advanced Paediatric Life Support (APLS), American Heart Association Pediatric Advanced Life Support Guidelines, and leading pediatric references including Nelson Textbook of Pediatrics, Paediatric Intensive Care by Tasker and McClure, Smith’s Anesthesia for Infants and Children, and the Oxford Handbook of Paediatrics. The study material also reflects emergency pediatric management principles discussed in peer-reviewed journals such as Pediatric Critical Care Medicine, Archives of Disease in Childhood, The Lancet Child & Adolescent Health, and Resuscitation. The document extensively reviews pediatric respiratory physiology and airway management including airway resistance, tidal volume calculations, minute ventilation, tracheal tube confirmation, end-tidal CO₂ monitoring, mechanical ventilation targets, severe asthma management, bronchiolitis treatment, croup therapy, nebulized adrenaline administration, and indications for pediatric intubation. Additional emergency medicine topics include distributive, hypovolemic, obstructive, cardiogenic, and dissociative shock; adrenaline dosing; amiodarone and adenosine administration; synchronized cardioversion; ventricular fibrillation (VF); pulseless ventricular tachycardia (pVT); advanced cardiac life support algorithms; and pediatric ECG interpretation including QRS, ST segment, and T-wave analysis. The study guide also provides detailed trauma and critical care review material including traumatic brain injury (TBI), intracranial pressure (ICP) management, tension pneumothorax, chest trauma, haemothorax, thoracostomy procedures, chest drain insertion landmarks, hypovolemic shock management, tranexamic acid (TXA) dosing, burns assessment using the Parkland Formula, trauma-induced coagulopathy, compartment syndrome, abdominal trauma, cervical spine stabilization, and the CABCDE trauma approach. Further topics include diabetic ketoacidosis fluid calculations, electrolyte emergencies such as hyperkalemia and hypocalcemia, seizure management, newborn resuscitation, neonatal oxygen targets, infant airway equipment sizing, defibrillation energy calculations, CPR ventilation rates, and post-resuscitation care. Students using this resource will strengthen their understanding of pediatric emergency assessment, advanced life support algorithms, critical care pharmacology, neonatal stabilization, trauma resuscitation, and evidence-based pediatric emergency medicine practices necessary for success in EPALS examinations and real-world emergency healthcare environments. The material is suitable for independent study, advanced pediatric life support courses, emergency nursing education, PICU training, pediatric simulation programs, clinical skills revision, and emergency medicine certification preparation. Keywords EPALS, pediatric advanced life support, pediatric emergency medicine, pediatric resuscitation, PALS exam, pediatric airway management, neonatal resuscitation, pediatric trauma, DKA management, asthma exacerbation, bronchiolitis treatment, croup management, epiglottitis, anaphylaxis management, pediatric CPR, pediatric critical care, PICU nursing, emergency nursing, pediatric ventilation, advanced airway support, pediatric ECG interpretation, VF and pVT, synchronized cardioversion, amiodarone dosing, adenosine SVT, adrenaline infusion, pediatric shock, hypovolemic shock, distributive shock, obstructive shock, dissociative shock, pediatric trauma protocols, tension pneumothorax, chest drain insertion, burns management, Parkland formula, raised intracranial pressure, TBI management, pediatric seizures, hyperkalemia treatment, neonatal life support, pediatric anaesthesia, pediatric pharmacology, resuscitation algorithms, oxygen therapy, pediatric fluid resuscitation, emergency medicine exam prep, pediatric intensive care, neonatal airway management, advanced pediatric emergency care

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EPALS 2026 Exam Questions
and Correct Answers | New
Update

What is Poiseuille's Law? - ANSWER ✔✔relates the resistance of a

gas flowing through a tube, to its length, the viscosity of the gas and the

radius of the tube.

A small decrease in airway radius results in huge increase to the

resistance of gas flow.


What factors are involved in Poiseuilles law? - ANSWER ✔✔Radius

of airway

Resistance of gas

,Length of airway

Viscosity of gas


Whats the difference in larynx position in the young child? - ANSWER

✔✔It lies higher in the neck


What is choanal atresia? - ANSWER ✔✔Congenital obstruction of

posterior nasal passages


How does the epiglottis compare in children vx adults - ANSWER

✔✔Epiglottis is larger and floppier in infants


What is the air-alveolar surface area for gas exchange at birth? -

ANSWER ✔✔3 m2 compared to 70m2 in an adult


Minute ventilation - ANSWER ✔✔tidal volume x respiratory rate


What is the main determinant of CO2 removal? - ANSWER

✔✔minute ventilation


Tidal volume - ANSWER ✔✔the volume of gas with each breath


What is the tidal volume throughout life? - ANSWER ✔✔constant 4-

6ml/kg

,What does the diaphragm do during inspiration? - ANSWER

✔✔descends creating negative pressure which draws air into the upper

airways and lungs


What is the circulating volume of an newborn? - ANSWER

✔✔80ml/kg (60-70 in adults)


What determines oxygen delivery? - ANSWER ✔✔arterial oxygen

content and cardiac output

How does cardiac output relative to body weight compare in infants vs

adults - ANSWER ✔✔Cardiac output is higher in infancy (largely

achieved by higher HR)


Why is bradycardia important in children - ANSWER ✔✔Cardiac

output is directly affected by HR


How to calculate MAP in acute conditions? - ANSWER ✔✔((2x

diastolic) + systolic) / 3 = MAP


How does MAP relate to cardiac output? - ANSWER ✔✔MAP = CO x

SVR

What formula can be used to estimate weight in a child 1-10 years? -

ANSWER ✔✔(age in years + 4) x 2

3
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, What causes grunting? - ANSWER ✔✔exhaling against a partially

closed glottis - it is an attempt to generate a positive end-expiratory

pressure that prevents airway collapse at the end of expiration


Do anaemia or jaundice affect pulse oximetry? - ANSWER ✔✔no


What are the 5 main categories of shock? - ANSWER

✔✔Hypovolaemic, distributive, cardiogenic, obstructive, dissociative


What are examples of distributive shock? - ANSWER ✔✔anaphylaxis

and sepsis - inadequate distribution of blood flow so that tissues have

inadequate supply


What are examples of obstructive shock? - ANSWER ✔✔cardiac

tamponade, tension pneumothorax, pulmonary embolism (obstruct blood

flow to/from the heart)


What are examples of dissociative shock? - ANSWER ✔✔anaemia,

carbon monoxide poisoning (where the oxygen carrying capacity of

blood is limited)


What is the equation for blood pressure? - ANSWER ✔✔BP = CO x

SVR

In hypovolaemia, what percentage of a child's circulating volume can be

lost before they develop hypotension? - ANSWER ✔✔40%

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