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PATH 370 Assessment 1 Study Guide: Foundations of Pathophysiology (Chapters 1, 2, 4 & 7)

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Comprehensive PATH 370 Assessment 1 review covering key concepts from Chapters 1, 2, 4, and 7, including cellular function, inflammation, immune responses, genetic disorders, disease mechanisms, tissue repair, and pathophysiological processes. Designed to help healthcare and nursing students strengthen understanding of disease development, clinical manifestations, and foundational pathology concepts for quizzes, exams, and coursework.

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Path 370
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The effect of stress on the immune system

a. may involve enhancement or impairment the immune system.
b. most often involves enhancement of the immune system.
c. is unknown.
d. has been demonstrated to be non-existent in studies.

a. may involve enhancement or impairment the immune system.

Metaplasia is

a. the disorganization of cells into various sizes, shapes, and arrangements.
b. an irreversible cellular adaptation.
c. the transformation of a cell type to malignancy.
d. the replacement of one differentiated cell type with another.

d. the replacement of one differentiated cell type with another.

Retroviruses are associated with human cancers, including

a. Burkitt lymphoma.
b. hepatic cancer.
c. Hodgkin's lymphoma.
d. pancreatic cancer.

a. Burkitt lymphoma.

An increase in organ size and function caused by increased workload is termed

a. metaplasia
b. atrophy.
c. inflammation.
d. hypertrophy.

d. hypertrophy.

Reperfusion injury to cells

a. results in very little cellular damage.
b. involves formation of free radicals.
c. results from calcium deficiency in cells.
d. occurs following nutritional injury.

b. involves formation of free radicals.

Your patient is scheduled for a staging procedure. She wants to know what that means. The correct
response is which of the following?

a. It is based on exploratory surgery.

, b. It is biochemical testing of tumor cells to determine the genetic basis of the tumor.
c. It is a histologic examination of tissues to determine the degree of tumor differentiation.
d. It is a procedure for determining the extent of tumor spread.

d. It is a procedure for determining the extent of tumor spread.

The primary adaptive purpose of the substances produced in the alarm stage is

a. invoke resting state.
b. energy and repair.
c. set a new baseline steady-state.
d. produce exhaustion.

b. energy and repair.

Paraneoplastic syndromes in cancer involve excessive production of substances by multiple means. A
common substance found in excessive amounts resulting from cancer paraneoplastic syndromes is

a. potassium
b. tumor necrosis factor
c. insulin
d. calcium

d. calcium

All the following stress-induced hormones increase blood glucose except

a. epinephrine.
b. norepinephrine.
c. aldosterone.
d. cortisol.

c. aldosterone.

Somatic death refers to death

a. of the entire organism.
b. secondary to brain damage.
c. of a body organ.
d. of nerve cells.

a. of the entire organism

Allostasis is best defined as

a. a state of equilibrium, of balance within the organism.
b. the overall process of adaptive change necessary to maintain survival and well-being.
c. steady-state.
d. the process by which the body heals following disease.

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Path 370
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