NR 566 Midterm NR566 MIDTERM EXAM
REVIEW /LATEST ADVANCED PHARMACOLOGY
FOR CARE OF FAMILY|AGRADE
What labs should be monitored with Phentermine and
Diethylpropion? What condition should we screen for? -
✔✔ANSWER ✔✔--baseline CMP (watch electrolytes and
creatinine)
-screen for depression
Which non-amphetamines are FDA approved for weight
loss that have lower abuse risk? - ✔✔ANSWER ✔✔-
Phentermine and Diethylpropion
,How does Phentermine and Diethylpropion promote
weight loss? - ✔✔ANSWER ✔✔--Promote weight loss by
decreasing appetite
-They are central nervous system (CNS) stimulants that
suppress appetite by increasing the availability of
norepinephrine at receptors in the brain
What is the maximum recommended duration of use for
non-amphetamines? - ✔✔ANSWER ✔✔-3 months or less
What drug schedule are Phentermine and Diethylpropion
under? - ✔✔ANSWER ✔✔-Schedule IV
Phentermine adverse effects - ✔✔ANSWER ✔✔--increase
HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - ✔✔ANSWER
✔✔-Increases satiety
,What are some Phentermine/topiramate contraindications
for use? - ✔✔ANSWER ✔✔-not approved in children and
contraindicated with severe hepatic impairment
How should we educate patient to take
Phentermine/topiramate to avoid insomnia? - ✔✔ANSWER
✔✔-given before 1600
What are some high-risk patient conditions that we should
use Phentermine/topiramate with caution? - ✔✔ANSWER
✔✔-hx drug abuse, glaucoma, pregnant, HTN,
hyperthyroidism
Phentermine/topiramate adverse effects - ✔✔ANSWER
✔✔-insomnia, nervousness, anxiety, depression, blurred
vision
Which of the following would be a contraindication to
prescribing phentermine/topiramate? Select all that apply.
- ✔✔ANSWER ✔✔-A) Glaucoma
B) Hypothyroidism
C) Hypertension
, D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and
reduces absorption of fat by 30%. - ✔✔ANSWER ✔✔-GI
tract
Take multivitamin ___hours before/after to supplement fat-
soluble vitamins that may not be absorbed well when
taking Orlistat. - ✔✔ANSWER ✔✔-2
Orlistat is OTC as 60 mg TID with meals. Not approved in
children <____. - ✔✔ANSWER ✔✔-12
Orlistat results in the least amount of weight loss of all.
How much? - ✔✔ANSWER ✔✔-2-3% body weight (7 lbs in
year)
REVIEW /LATEST ADVANCED PHARMACOLOGY
FOR CARE OF FAMILY|AGRADE
What labs should be monitored with Phentermine and
Diethylpropion? What condition should we screen for? -
✔✔ANSWER ✔✔--baseline CMP (watch electrolytes and
creatinine)
-screen for depression
Which non-amphetamines are FDA approved for weight
loss that have lower abuse risk? - ✔✔ANSWER ✔✔-
Phentermine and Diethylpropion
,How does Phentermine and Diethylpropion promote
weight loss? - ✔✔ANSWER ✔✔--Promote weight loss by
decreasing appetite
-They are central nervous system (CNS) stimulants that
suppress appetite by increasing the availability of
norepinephrine at receptors in the brain
What is the maximum recommended duration of use for
non-amphetamines? - ✔✔ANSWER ✔✔-3 months or less
What drug schedule are Phentermine and Diethylpropion
under? - ✔✔ANSWER ✔✔-Schedule IV
Phentermine adverse effects - ✔✔ANSWER ✔✔--increase
HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - ✔✔ANSWER
✔✔-Increases satiety
,What are some Phentermine/topiramate contraindications
for use? - ✔✔ANSWER ✔✔-not approved in children and
contraindicated with severe hepatic impairment
How should we educate patient to take
Phentermine/topiramate to avoid insomnia? - ✔✔ANSWER
✔✔-given before 1600
What are some high-risk patient conditions that we should
use Phentermine/topiramate with caution? - ✔✔ANSWER
✔✔-hx drug abuse, glaucoma, pregnant, HTN,
hyperthyroidism
Phentermine/topiramate adverse effects - ✔✔ANSWER
✔✔-insomnia, nervousness, anxiety, depression, blurred
vision
Which of the following would be a contraindication to
prescribing phentermine/topiramate? Select all that apply.
- ✔✔ANSWER ✔✔-A) Glaucoma
B) Hypothyroidism
C) Hypertension
, D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and
reduces absorption of fat by 30%. - ✔✔ANSWER ✔✔-GI
tract
Take multivitamin ___hours before/after to supplement fat-
soluble vitamins that may not be absorbed well when
taking Orlistat. - ✔✔ANSWER ✔✔-2
Orlistat is OTC as 60 mg TID with meals. Not approved in
children <____. - ✔✔ANSWER ✔✔-12
Orlistat results in the least amount of weight loss of all.
How much? - ✔✔ANSWER ✔✔-2-3% body weight (7 lbs in
year)
