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Questions, Detailed Rationales, and Expert Answer
Explanations
You are caring for an adult, obese patient who is 5 days post-discharge from a hospitalization
due to a DVT. Which instructions would you NOT give to minimize the recurrence of a
thrombosis?
• A. Start vigorous exercise immediately
• B. Use support stockings daily
• C. Report bleeding of gums and bruising
• D. Avoid prolonged inactivity
• Correct Answer: A
• Rationale: Initiating vigorous exercise shortly after a acute deep vein thrombosis (DVT)
exponentially elevates intravascular shear stress, increasing the risk of clot dislodgment
and subsequent life-threatening pulmonary embolism (PE). Activity should be low-
impact and titrated gradually under direct medical guidance.
You are evaluating a 65-year-old male with known PVD and who is a current smoker. What is
your initial evaluation?
• A. Order a venous reflex study
• B. Assess the pedal and posterior tibial pulses
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• C. Order compression stockings
• D. Order a venogram
• Correct Answer: B
• Rationale: In a patient with known peripheral vascular (arterial) disease (PVD/PAD),
performing a physical assessment of the dorsalis pedis and posterior tibial pulses is the
mandatory initial step to determine the degree of arterial insufficiency.
⚠️ Clinical Warning: Ordering compression stockings (Option C) without checking arterial
patency is strictly contraindicated, as compression can totally occlude compromised arterial flow
and induce tissue necrosis.
You review a lower extremity duplex study to discover the diagnosis of a non-septic,
superficial thrombophlebitis. What is the recommended treatment?
• A. Cool compresses, elevate extremity, ibuprofen 400mg TID, Keflex 500 mg TID for 10
days
• B. Warm compresses, elevate extremity, naproxen sodium 500mg BID with food
• C. Hospital admission, IV antibiotics
• D. Hospital admission, IV heparin, then warfarin PO for 3-6 months
• Correct Answer: B
• Rationale: Non-septic superficial thrombophlebitis is an inflammatory process rather
than an infectious or deep thrombotic event. It is managed conservatively with warm
compresses to promote localized blood flow, limb elevation to facilitate venous return,
and NSAIDs (like naproxen) to inhibit prostaglandin synthesis, managing pain and
inflammation.
A 35-year-old female presents with intermittent episodes of color changes in her fingertips
(blue, white, red), numbness, and tingling, lasting 2-3 hours. Symptoms worsen in winter
months. What is the possible diagnosis?
• A. Diabetic neuropathy
• B. Poor circulation
• C. Raynaud's phenomenon
• D. PVT
• Correct Answer: C
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• Rationale: The classic triphasic color response—pallor (white/vasospasm), cyanosis
(blue/hypoxia), and rubor (red/hyperemia)—triggered predictably by cold temperatures
or emotional stress is pathognomonic for Raynaud's phenomenon.
You are treating a 35-year-old female with Raynaud's phenomenon. She is a smoker and works
in an unheated warehouse. What education should you provide? (Select all that apply.)
• A. Wear gloves and thick socks
• B. Take warm showers daily
• C. Change jobs
• D. Smoking cessation and avoid cold weather
• Correct Answers: A, D
• Rationale: Primary management focuses on preventing vasospastic triggers. Nicotine is a
potent vasoconstrictor that drastically exacerbates symptoms, making smoking
cessation critical. Environmental protection via heavy insulation (gloves and socks)
directly prevents the cold-induced digital vasospasms.
ENT & Respiratory Conditions
A 64-year-old presents with tonsillar exudate, anterior cervical adenopathy, fever, and no
cough. What is the most likely causative agent?
• A. Group A beta-hemolytic streptococcus
• B. Rhinovirus
• C. Epstein-Barr virus
• D. Haemophilus influenzae
• Correct Answer: A
• Rationale: Utilizing the Centor Criteria for pharyngitis, this patient scores a 4 (tonsillar
exudates, tender anterior cervical lymphadenopathy, history of fever, and the structural
absence of a cough). This clinical presentation yields a very high positive predictive value
for Group A beta-hemolytic streptococcus (GABHS).
An 18-year-old male has a persistent sore throat, fever, and malaise not relieved with
penicillin therapy. What should you order next?
• A. A throat culture
• B. A monospot test
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• C. A rapid antigen test
• D. A Thayer-Martin plate test
• Correct Answer: B
• Rationale: A severe, febrile pharyngitis that fails to respond to beta-lactam antibiotics
(penicillin) strongly points toward a viral etiology, specifically Infectious Mononucleosis
(Epstein-Barr virus). A Heterophile Antibody Test (Monospot) is the appropriate
diagnostic step.
A 19-year-old male is diagnosed with mononucleosis. Which statement is true?
• A. Mono is rarely contagious
• B. John should avoid contact sports and heavy lifting
• C. The offending organism is bacterial and should be treated with antibiotics
• D. Convalescence is usually only a few days, and John should be back to normal in a week
• Correct Answer: B
• Rationale: Lymphocyte proliferation during an EBV infection routinely causes benign
splenomegaly. To eliminate the catastrophic risk of splenic rupture, patients must strictly
avoid contact sports, heavy lifting, or vigorous activities for a minimum of 3–4 weeks
from symptom onset.
A 52-year-old male with chronic allergic rhinitis is taking cimetidine (Tagamet) for GERD.
Which medication should you NOT prescribe?
• A. A first-generation antihistamine
• B. A decongestant
• C. A second-generation antihistamine
• D. A topical nasal corticosteroid
• Correct Answer: A
• Rationale: Cimetidine is a potent hepatic CYP450 enzyme inhibitor. Concomitant
administration with first-generation antihistamines (e.g., diphenhydramine) slows the
clearance of the antihistamine, severely amplifying central nervous system (CNS) side
effects like extreme sedation, anticholinergic toxicity, and cognitive impairment.
A 25-year-old woman with seasonal allergic rhinitis asks when the pollen count is lowest. You
respond:
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