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PHARMACOLOGY EXAM II ATI QUESTIONS AND CORRECT VERIFIED ANSWERS ALREADY GRADED A+

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Pass your ATI Pharmacology Exam II with confidence using the most current and comprehensive test bank available for the 2026 academic year. This resource features actual ATI-style exam questions with verified correct answers—already graded A+ by successful nursing students. Covering over 150 high-yield questions, this guide mirrors the exact content domains tested on ATI Pharmacology Exam II: Cardiovascular Pharmacology: Verapamil (grapefruit juice causes hypotension), losartan (facial edema/angioedema requires reporting), nitroglycerin (headache as adverse effect), dobutamine interactions (MAOIs, general anesthetics, tricyclic antidepressants, beta blockers), propranolol (avoid NSAIDs), quinidine (monitor pulse rate), transdermal nitroglycerin (apply to hairless area, rotate sites, remove for 10-12 hours daily to prevent tolerance), milrinone (contraindicated in acute MI), carvedilol with oral antidiabetics (increased risk of hypoglycemia, masks tachycardia), verapamil contraindicated in second-degree AV block, procainamide (short-term use only due to serious adverse effects), digoxin toxicity (antigen-binding fragments/digoxin immune Fab as antidote), reserpine contraindicated in depression. Antihypertensives & Diuretics: Loop diuretics (hypokalemia manifestations: thready irregular pulse, orthostatic hypotension, confusion), hydrochlorothiazide (ineffective with GFR 10 mL/min, causes hyperuricemia in gout), spironolactone (potassium 5.2 mEq/L requires immediate intervention), aliskiren (hyperkalemia, throat swelling/angioedema, cough), captopril adverse effects (rash, distorted taste, tongue swelling, dry cough – report as may need discontinuation), losartan (facial edema = angioedema), thiazide diuretics (increase potassium intake with raisins/dried fruits). Lipid-Lowering Agents: Simvastatin (muscle pain/myopathy requires reporting, can progress to rhabdomyolysis), gemfibrozil (report muscle tenderness, gallstone symptoms, liver function testing), atorvastatin + gemfibrozil (increased risk of myopathy). Respiratory Pharmacology: Albuterol (tremors as adverse effect, use before beclomethasone, palpitations indicate serious effect), beclomethasone (rinse mouth after use to prevent candidiasis), prednisone (weight gain, avoid NSAIDs, must taper slowly, osteoporosis/peptic ulcer risk), dextromethorphan (sedation as adverse effect), diphenhydramine (dry mouth, drowsiness, urinary hesitation), fluticasone (takes up to 3 weeks for maximum effect), montelukast (take once daily in evening, depression as adverse effect), cromolyn sodium (bitter aftertaste, prevents mast cell release), ipratropium (urinary retention, dry mouth, wait 5 min between inhalers), guaifenesin (expectorant – reduces surface tension), acetylcysteine (mucolytic for thick secretions), theophylline toxicity (seizures), pseudoephedrine (cautious with coronary artery disease, restlessness/insomnia/anxiety, legal restrictions due to drug abuse), phenylephrine (rebound congestion after 10 days of use), codeine (most important assessment = respirations). Hematologic & Coagulation: Warfarin (monitor PT, ginger root interaction, not for dissolving clots), heparin (does NOT dissolve clots – prevents new clots from forming), warfarin + heparin overlap (warfarin takes several days to work), packed RBC transfusion reaction (chills, back pain, hypotension – STOP infusion first), hemophilia A (recombinant factor VIII for wisdom teeth extraction). Fluid & Electrolyte Balance: Hypokalemia (prominent U wave on EKG), fluid overload findings (increased HR, BP, RR), dehydration signs (decreased intake/output, furrowed tongue, mental confusion), hydrochlorothiazide ineffective with renal insufficiency (GFR 10 mL/min). Medication Administration Calculations: Packed RBCs 250 mL over 2 hours, drop factor 15 gtts/mL = 31 gtts/min. Drug Class Summaries: Glucocorticoids (budesonide, beclomethasone, fluticasone – anti-inflammatory, oropharyngeal candidiasis, rinse mouth), prednisone (oral anti-inflammatory, taper slowly), montelukast (leukotriene modifier, once daily evening), cromolyn (mast cell stabilizer, bitter taste), omalizumab (anti-IgE, anaphylaxis risk), beta-2 adrenergic agonists (albuterol – bronchodilation, tremors, palpitations), SABA vs. LABA, theophylline (methylxanthine, monitor levels, interacts with caffeine/tobacco), ipratropium (anticholinergic, urinary retention, dry mouth), antihistamines (diphenhydramine sedation, cetirizine/fexofenadine/loratadine second-gen), sympathomimetics (phenylephrine, pseudoephedrine – rebound congestion, abuse potential). Perfect for nursing students preparing for ATI Pharmacology Proctored Exams, NCLEX-RN, HESI, and course finals. Each answer includes the verified correct response to ensure exam readiness.

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Instelling
Pharmacology II ATI 2026
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Pharmacology II ATI 2026

Voorbeeld van de inhoud

PHARMACOLOGY EXAM II ATI QUESTIONS AND
CORRECT VERIFIED ANSWERS ALREADY GRADED
A+




A nurse is caring for a client who has a new prescription for verapamil
to treat atrial fibrillation. The nurse should instruct the client to avoid
drinking grapefruit juice while taking verapamil because it can cause the
client to experience which of the following conditions?

A) Tachycardia
B) Dehydration
C) Diarrhea
D) Hypotension - ANS... -D) Hypotension

Large amounts of grapefruit juice can increase blood levels of verapamil
by inhibiting its metabolism. An excess amount of the drug in the body
can intensify otherwise therapeutic effects like hypotension, causing
serious risk for syncope and dizziness.

A nurse is providing teaching to a client who has a new prescription for
losartan to treat hypertension. The nurse should instruct the client that
which of the following findings could indicate an adverse reaction to the
drug and needs to be reported?

A) Facial edema
B) Sleepiness
C) Peripheral edema
D) Constipation - ANS... -A) Facial edema

Losartan, an angiotensin II receptor blocker, can cause angioedema,
which often manifests as swelling around the eyes and lips. Clients who

,develop this adverse effect should stop taking the drug and seek medical
attention.

A nurse is caring for a client who is taking a diuretic. The nurse should
instruct the client to include which of the following foods in their diet to
increase potassium intake?

A) Raisins
B) Cabbage
C) Cheese
D) Eggs - ANS... -A) Raisins

Diuretics can deplete the body of potassium, so the nurse should instruct
the client to include potassium-rich foods in their diet, such as raisins
and other dried fruits.

A nurse is teaching a client who has a new prescription for nitroglycerin.
The nurse should instruct the client that which of the following
manifestations is a potential adverse effect of this drug?

A) Headache
B) Constipation
C) Hypertension
D) Hyperglycemia - ANS... -A) Headache

Adverse effects of nitrates, such as nitroglycerin, include headaches,
which can be severe at the beginning of nitrate therapy but decrease in
severity with continued exposure to nitrates.

A nurse is caring for a client who has a new prescription for dobutamine.
The nurse should clarify the prescription with the provider if the client is
receiving which of the following types of drugs? (Select all that apply)

A) ACE inhibitor
B) MAOI

,C) General anesthetic
D) Tricyclic antidepressant
E) Beta blocker - ANS... -B, C, D, and E

B) MAOIs can cause toxicity when clients take them while also taking
dobutamine. This significantly increases the client's risk for
tachydysrhythmias.

C) General anesthetics can cause dysrhythmias when clients take them
while also taking dobutamine.

D) Tricyclic antidepressants can cause toxicity when clients take them
while also taking dobutamine. This significantly increases the client's
risk for tachydysrhythmias.

E) Beta blockers, such as propranolol, can decrease the effects of
dobutamine.

A nurse is caring for a client who has a new prescription for propanolol
to treat a tachydysrhythmia. The nurse should instruct the client to avoid
taking which of the following types of over-the-counter drugs while
taking propanolol?

A) Antihistamines
B) Potassium supplements
C) NSAIDs
D) Vitamin C - ANS... -C) NSAIDs

NSAIDs can interact with propranolol and decrease the anti-
hypertensive action because vasoconstriction can occur in some COX-2
inhibitors. The nurse should instruct the client to avoid taking NSAIDs
and propranolol at the same time.

A nurse is teaching a client who has a new prescription for quinidine.
Which of the following statements should the nurse include?

, A) "Monitor your pulse rate and report changes."
B) "Remain upright for 30 minutes after taking this medication."
C) "This medication can decrease digoxin levels."
D) "This medication can cause urinary incontinence." - ANS... -A)
"Monitor your pulse rate and report changes."

Sodium channel blockers, like quinidine, can worsen dysrhythmias, or
cause new ones. The nurse should teach the client to monitor their pulse
rate and report changes from prescribed parameters. It can be helpful to
instruct the client to keep a written record of their pulse rate for the
provider.

A nurse is assessing a client who is taking a loop diuretic and is
experiencing a thready, irregular pulse, orthostatic hypotension, and
confusion. The nurse should identify that these manifestations indicate
which of the following adverse effects?

A) Hypokalemia
B) Hypoglycemia
C) Hypouricemia
D) Hyponatremia - ANS... -A) Hypokalemia

Manifestations of hypokalemia include a thready, irregular pulse,
orthostatic hypotension, anxiety, confusion, skeletal muscle weakness,
hypoactive bowel sounds, polyuria, nausea, and vomiting.

A nurse is caring for a client who will begin using transdermal
nitroglycerin to treat angina pectoris. When speaking to the client about
the drug, which of the following instructions should the nurse include?
(Select all that apply)

A) "Apply a new patch at the onset of anginal pain."
B) "Apply the patch to dry skin and cover the area with plastic wrap."
C) "Apply the patch to a hairless area and rotate sites."

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