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musculoskeletal Pathology Statistics
- Generally self limiting
- One of the most common reasons for Visits to clinician.
- Diagnostically challenging (Many resemble each other)
- Take time often to evolve into diagnosable disease.
Musculoskeletal Differential Diagnoses Categories
-Trauma
- Infection
- Metabolic disorders
- Circulatory disorder
- Tumor
- Synovial conditions
- Congenital or developmental problems
- Degenerative Problems
Internal derangement
disruption of the structures inside a joint
Systemic rheumatic disease
Inflammation is primary, resulting from an immune
response, probably autoimmune in origin
Entrapment neuropathy
pain and loss of function resulting from a nerve passing through a physiologic
space that is narrowed secondary to acute or chronic trauma or inflammation
,gouty arthritis (gout)
inflammation and painful swelling of joints caused by excessive uric acid in the
body
paraneoplastic syndrome
medical condition caused by tumor secretions (hormones, cytokines, TNF,
Interleukin-1), may cause hypercalcermia, hypoglycemia, SIADH
Mononeuritis
inflammation of a single nerve
radiculopathy (radiculitis)
inflammation of the nerve root associated with the spinal column
myelopathy
any pathologic change or disease in the spinal cord
transverse myelitis
inflammation of the spinal cord
reflex sympathetic dystrophy
- Increase in sympathetic activity causing a release of norepinephrine in periphery
and subsequent vasoconstriction of blood vessels resulting in pain and increase in
sensitivity to peripheral stimulation. intense burning and pain in affected
extremity, spreads proximally
Giant cell arteritis
temporal artery granulomatous vasculitis; ipsilateral blindness (ophthalmic artery)
compartment syndrome
involves the compression of nerves and blood vessels due to swelling within the
enclosed space created by the fascia that separates groups of muscles
Musculoskeletal Differentials
, -Soft tissue injury
- Internal derangement
- Fracture
- Infection
- Systemic rheumatic disease
- gout
-pseudogout
- Compartment Syndrome
- Entrapment neuropathy
- mononeuritis
- motor neuron disease
- Radiculopathy
- Myositis
- Metabolic myopathy
- Paraneoplastic Syndrome
- myelopathy
Transverse Myelitis
Articular structures
synovium, synovial fluid, articular cartilage, intraarticular ligaments, joint capsule,
juxtaarticular bone
- Disorders are characterized by:
- deep or diffuse pain
- Pain with both active and passive ROM of joint
- Swelling
Articular Disorder Classifcations
Monoarticular
- One joint effected
Periarticular
- Two to four joints effected
Polyarticular
- More than four joints