2027 NEWEST ACTUAL EXAM WITH COMPLETE
QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) |ALREADY GRADED A+||BRAND
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what factors can affect distribution
protein binding %, Plasma protein and albumin levels, liver disease,
kidney disease, malnourished , and hypoalbuminemia
where is the primary site for metabolism
liver
what can liver disease do to a drug
cause decrease drug metabolism rates causing toxicity
What is a half-life?
the time it takes for one half of the drug concentration to be eliminated
,what is the main route of excretion
kidneys
what can occur with kidney disease
accumulation of a drug
What is creatinine clearance?
lab test to determine kidney function
what is normal kidney function
85-135 ml/min
, how does age affect excretion
excretion decreases with age and may need to have medication
dosage adjusted
What is pharmacodynamics?
study of drug concentration and what it does to the body
What is the Receptor theory
drugs act through receptors by binding to the receptor site to
produce or block a response
What is an agonist?
produce a response
What is an antagonist?
They block the action of an agonist getting to the receptor to elicit
a response, therefore no response is made