Pharmacotherapeutics I NSG3022 Questions With Complete
Solutions
Abscesses and tumors with regard to blood flow to tissues.
Correct Answers Low regional blood flow impacts therapy.
Pus-filled pockets, not internal blood vessels.
Solid tumors have limited blood supply.
ADR is defined by? Correct Answers The WHO as any
noxious unintended and undedesired efect that occurs at normal
drug doses.
Excludes excessive dosages.
Can range from annoying to life-threatening
Can OTC interact with prescription drugs? Correct Answers
Yes OTC can interact.
Chemical Stability Correct Answers Some drugs lose their
stabilty/effectiveness during storage.
Clinical Pharmacology Correct Answers the study of
medication in humans. Used on patients and healty volenteers.
Dose-Response Relationships are Correct Answers
Relationship between the size of an administered dose and the
intensity of the response produced.
Determines; The maximum amount of drug we can use
The minimum amount of drug we can use.
How much we need to increase the dosage to produce the
desired increase in response.
,As the dosage increases, the response becomes progressively
larger.
Tailor treatment by increased/decreased dosage until desired
intensity of response is achieved.
Three phases occur.
Drug Correct Answers any chemical that can affect living
processes
Drug therapy and pediatric patients Correct Answers all
patients younger than 16 yrs.
respond differently to drugs than the rest of the population.
Ongoing growth and developmentdr
drug therapy in geriatric patients Correct Answers
Disproportionately high prescription use exists.
Geriatric patients have more adverse drug reactions and drug-
drug interactions.
Ease of administration of a drug Correct Answers Can enhance
patient adherence; can decrease administration errors.
Effectiveness of a drug Correct Answers the most important
property a drug can have; it elicits the responses for which it is
given; no effect=no justification of use.
Factors that determine the intensity of drug responses. Correct
Answers Administration; dosage, route and timing; medication
errors, patient adherance.
, Pharacokinetics; absorption, distribution, metabolism, excretion;
process determine how much administration dose gets to its sites
of action.
Pharmacodynamics; is the impact of drugs on the body. I.E.
drug-receptor interation, patient's functional state, placebo
effects.
Freedom of drug interations Correct Answers An ideal drug
will not interact with other agents; unfortunetely, few drugs are
devoid of significant interations.
Geriatric patients and absorption issues Correct Answers
Geriatric patients rate of absorption may be slower.
hat are the steps in renal drug excretion? Correct Answers
Glomerular filtration, Passive tubular reabsorption, and Active
tubular secretion.
How do you identifiy an adverse drug reaction? Correct
Answers Can be very difficult to determine whether a specfic
drug is responsible for an observed adverse event.
How does blood flow to tissues? Correct Answers Drugs are
carried by the blood to tissues and organs of the body.
Blood flow determines the rate of deliery.
How drugs enter the cells Correct Answers Some must enter
cells to reach the site of action.
Most must enter cells to undergo metabolism and excretion.
Solutions
Abscesses and tumors with regard to blood flow to tissues.
Correct Answers Low regional blood flow impacts therapy.
Pus-filled pockets, not internal blood vessels.
Solid tumors have limited blood supply.
ADR is defined by? Correct Answers The WHO as any
noxious unintended and undedesired efect that occurs at normal
drug doses.
Excludes excessive dosages.
Can range from annoying to life-threatening
Can OTC interact with prescription drugs? Correct Answers
Yes OTC can interact.
Chemical Stability Correct Answers Some drugs lose their
stabilty/effectiveness during storage.
Clinical Pharmacology Correct Answers the study of
medication in humans. Used on patients and healty volenteers.
Dose-Response Relationships are Correct Answers
Relationship between the size of an administered dose and the
intensity of the response produced.
Determines; The maximum amount of drug we can use
The minimum amount of drug we can use.
How much we need to increase the dosage to produce the
desired increase in response.
,As the dosage increases, the response becomes progressively
larger.
Tailor treatment by increased/decreased dosage until desired
intensity of response is achieved.
Three phases occur.
Drug Correct Answers any chemical that can affect living
processes
Drug therapy and pediatric patients Correct Answers all
patients younger than 16 yrs.
respond differently to drugs than the rest of the population.
Ongoing growth and developmentdr
drug therapy in geriatric patients Correct Answers
Disproportionately high prescription use exists.
Geriatric patients have more adverse drug reactions and drug-
drug interactions.
Ease of administration of a drug Correct Answers Can enhance
patient adherence; can decrease administration errors.
Effectiveness of a drug Correct Answers the most important
property a drug can have; it elicits the responses for which it is
given; no effect=no justification of use.
Factors that determine the intensity of drug responses. Correct
Answers Administration; dosage, route and timing; medication
errors, patient adherance.
, Pharacokinetics; absorption, distribution, metabolism, excretion;
process determine how much administration dose gets to its sites
of action.
Pharmacodynamics; is the impact of drugs on the body. I.E.
drug-receptor interation, patient's functional state, placebo
effects.
Freedom of drug interations Correct Answers An ideal drug
will not interact with other agents; unfortunetely, few drugs are
devoid of significant interations.
Geriatric patients and absorption issues Correct Answers
Geriatric patients rate of absorption may be slower.
hat are the steps in renal drug excretion? Correct Answers
Glomerular filtration, Passive tubular reabsorption, and Active
tubular secretion.
How do you identifiy an adverse drug reaction? Correct
Answers Can be very difficult to determine whether a specfic
drug is responsible for an observed adverse event.
How does blood flow to tissues? Correct Answers Drugs are
carried by the blood to tissues and organs of the body.
Blood flow determines the rate of deliery.
How drugs enter the cells Correct Answers Some must enter
cells to reach the site of action.
Most must enter cells to undergo metabolism and excretion.
