BIOC3022 EXAM 4 QUESTIONS WITH
100% VERIFIED ANSWERS
\.Can fats provide energy under anaerobic conditions? - ANSWERS-No;
derived from Krebs and ETC
\.Effect of hormones on lipid mobilization - ANSWERS-Adrenaline and
glucagon activate PKA which activates triacylglycerol lipase
\.Glycerol advantage - ANSWERS-Costs 1 ATP per 3 C - same, but now
get NADH
\.Similarities between B-oxidation and phase 3 of krebs - ANSWERS-1.
both start with two methylenes: acyl-CoA vs succinate 2. They are
oxidizes to a double bond, producing FADH2; succinate dehydro in krebs
3. double bond hydrated to form an alcohol: fumarase in krebs
4. alcohol is oxidized to ketone, producing NADH: malate dehdyro in
krebs
\.What does biosynthesis rely on - ANSWERS-NADP+/NADPH
, \.Output of beta oxidation - ANSWERS-1 NADH and 1 FADH2 per
\.How many ATP from each acetyl CoA - ANSWERS-12 ATP
\.Does fatty acid synthesis use FADH2 - ANSWERS-No, both enzymes
NADH dependent
\.Regulation of HMG-CoA Reductase - ANSWERS-1. Reversibly
inactivated by phosphorylation
2. Degraded in response to high cholesterol
3. Regulated at the level of transcription
\.Aspirin - ANSWERS-acetylates COX 1 to inactivate
\.ibuprofen - ANSWERS-inhibits COX1 without covalent modification
\.Acetominophen - ANSWERS-Inhibits COX protein, metabolized by a
cytochrome P450 in liver - toxic
\.COX1 - ANSWERS-makes thromboxane - promotes platelet clumping,
vasoconstrictor, inhibited by aspirin
100% VERIFIED ANSWERS
\.Can fats provide energy under anaerobic conditions? - ANSWERS-No;
derived from Krebs and ETC
\.Effect of hormones on lipid mobilization - ANSWERS-Adrenaline and
glucagon activate PKA which activates triacylglycerol lipase
\.Glycerol advantage - ANSWERS-Costs 1 ATP per 3 C - same, but now
get NADH
\.Similarities between B-oxidation and phase 3 of krebs - ANSWERS-1.
both start with two methylenes: acyl-CoA vs succinate 2. They are
oxidizes to a double bond, producing FADH2; succinate dehydro in krebs
3. double bond hydrated to form an alcohol: fumarase in krebs
4. alcohol is oxidized to ketone, producing NADH: malate dehdyro in
krebs
\.What does biosynthesis rely on - ANSWERS-NADP+/NADPH
, \.Output of beta oxidation - ANSWERS-1 NADH and 1 FADH2 per
\.How many ATP from each acetyl CoA - ANSWERS-12 ATP
\.Does fatty acid synthesis use FADH2 - ANSWERS-No, both enzymes
NADH dependent
\.Regulation of HMG-CoA Reductase - ANSWERS-1. Reversibly
inactivated by phosphorylation
2. Degraded in response to high cholesterol
3. Regulated at the level of transcription
\.Aspirin - ANSWERS-acetylates COX 1 to inactivate
\.ibuprofen - ANSWERS-inhibits COX1 without covalent modification
\.Acetominophen - ANSWERS-Inhibits COX protein, metabolized by a
cytochrome P450 in liver - toxic
\.COX1 - ANSWERS-makes thromboxane - promotes platelet clumping,
vasoconstrictor, inhibited by aspirin
