VIRUS FAMILY & DISEASE DIAGNOSIS: 200 QUESTIONS WITH 100% CORRECT ANSWERS

VIRUS FAMILY & DISEASE DIAGNOSIS:
200 QUESTIONS WITH 100% CORRECT
ANSWERS



DNA VIRUSES
Parvoviridae
1. Which virus family contains the smallest DNA
viruses?
a) Adenoviridae
b) Herpesviridae
c) Parvoviridae ✓
d) Poxviridae
2. A child presents with "slapped cheek" rash and
arthralgia. The most likely cause is:
a) Rubella virus
b) Parvovirus B19 ✓
c) Human herpesvirus 6
d) Measles virus

, 3. Parvovirus B19 infection during pregnancy can lead
to:
a) Congenital cataracts
b) Hydrops fetalis ✓
c) Microcephaly
d) Intracranial calcifications
4. A patient with sickle cell disease develops severe
anemia and reticulocytopenia. The most likely virus
is:
a) Epstein-Barr virus
b) Cytomegalovirus
c) Parvovirus B19 ✓
d) Adenovirus
5. The receptor for Parvovirus B19 on erythroid
progenitor cells is:
a) CD4
b) CD21
c) P antigen (globoside) ✓
d) ACE2
Papillomaviridae

,6. Human papillomavirus (HPV) types 16 and 18 are
most strongly associated with:
a) Common warts
b) Cervical cancer ✓
c) Laryngeal papilloma
d) Plantar warts
7. Which HPV type is most commonly associated with
common skin warts (verruca vulgaris)?
a) HPV-6
b) HPV-11
c) HPV-2 ✓
d) HPV-16
8. A patient presents with recurrent respiratory
papillomatosis. The most common causative HPV
types are:
a) HPV-16, HPV-18
b) HPV-6, HPV-11 ✓
c) HPV-1, HPV-2
d) HPV-31, HPV-33
9. The HPV proteins that inactivate p53 and Rb tumor
suppressors are:

, a) E1 and E2
b) E5 and E6
c) E6 and E7 ✓
d) L1 and L2
10. A vaccine that prevents cervical cancer is
primarily directed against:
a) HPV L1 capsid protein ✓
b) HPV E6 oncoprotein
c) HPV E7 oncoprotein
d) HPV E2 protein
Polyomaviridae
11. JC virus is the causative agent of:
a) Progressive multifocal leukoencephalopathy (PML)
✓
b) Hemorrhagic cystitis
c) Merkel cell carcinoma
d) Cervical cancer
12. BK virus is most commonly associated with:
a) PML
b) Hemorrhagic cystitis in transplant patients ✓