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HESI Biology | 2026 Updated Practice Questions and Answers for Nursing Entrance Exam Preparation

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This document contains HESI Biology practice questions and answers designed to support nursing school entrance exam preparation. It covers essential biology concepts including cell structure, genetics, human body systems, and basic biochemical processes commonly assessed in the HESI A2 exam. The material is structured to strengthen foundational science knowledge and improve test-taking performance. It is suitable for revision, practice, and self-assessment.

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Instelling
Human Biology
Vak
Human biology

Voorbeeld van de inhoud

HESI Biology
Study online at https://quizlet.com/_essfmv

1. What is the first step of cellular Glycolysis
respiration when glucose is con-
verted to pyruvate?

Glycolysis
The Krebs cycle
Electron transport chain
The Calvin cycle

2. A clinical researcher adminis- Placebo
tered a pill with no therapeutic
value to his subject. Which of
the following best describes this
treatment?

Evaluation
Double-blind
Placebo
Experimentation

3. Bony fishes belong to Phylum Kingdom
Chordata. Which of the following
levels of classification is more -Kingdom is a higher or more inclusive
inclusive than this level? level of the hierarchical system of classi-
fication than the phylum level.
Kingdom
Class
Order
Family

4. Which of these defines specific The amount of heat needed to raise the
heat? temperature of one gram of a substance
by one degree celsius
The amount of heat needed to
reduce the temperature of one -The amount of heat needed to raise the
gram of a substance by one de- temperature of one gram of a substance
gree celsius by one degree celsius is called specific
heat. The unit of specific heat is joules per
The amount of heat needed to gram per degree (J/g°C).


, HESI Biology
Study online at https://quizlet.com/_essfmv
raise the temperature of one
kilogram of a substance by one
degree celsius

The amount of heat needed to
raise the temperature of one
gram of a substance by one de-
gree celsius

The amount of heat needed to
reduce the temperature of one
kilogram of a substance by one
degree celsius

5. Polarity allows water to be a solvent
good __________.

solvent
solute
molecule
solution

6. How are carbohydrates ab- Carbohydrates are turned into glucose
sorbed into the bloodstream? and absorbed into the blood via the walls
of the small intestine.
Carbohydrates are turned into
glucose and absorbed into the - When your stomach digests food, car-
blood via the walls of the small bohydrates (sugars and starches) in the
intestine. food you ate gets broken down into an-
other type of smaller sugar, called glu-
Carbohydrates are turned into cose. The small intestines absorb the glu-
disaccharides and absorbed cose and then release it into the blood-
into the blood via the walls of the stream.
stomach.

Carbohydrates are turned into
fatty acids and absorbed into
the blood via the walls of the
large intestine.



, HESI Biology
Study online at https://quizlet.com/_essfmv


Carbohydrates are turned into
oxygen and are absorbed into
the blood via the lungs.

7. Humans and other animals re- Protein
quire nitrogen; however, they
cannot obtain it from the air -Animals and humans obtain the nitrogen
or soil. What must animals con- they require by consuming protein. Pro-
sume in order to obtain the nitro- teins are made of carbon, hydrogen, oxy-
gen they need? gen, and nitrogen, which are arranged as
chains (polymers) of amino acids.
Lipids
Protein
Glucose
Carbohydrates

8. Which of the following best de- Polymers of amino acids
scribes the structure of pro-
teins?

Polymers of steroids
Polymers of fatty acids
Polymers of nucleic acids
Polymers of amino acids

9. All metabolic reactions in a cell Enzymes
are catalyzed by which of the fol-
lowing? -Enzymes are a type of protein. They
catalyze (cause or accelerate) different
Phospholipids reactions and processes. Almost all cel-
Enzymes lular function is catalyzed by some type
Steroids of enzyme.
Amino acids

10. Cells with a high rate of protein Ribosomes
synthesis generally have a large
number of: -Ribosomes are responsible for protein
synthesis. Ribosomes read RNA pro-
Mitochondria duced in the nucleus and translate the


, HESI Biology
Study online at https://quizlet.com/_essfmv
Lysosomes genetic instructions provided to produce
Ribosomes proteins. Cells with a high rate of protein
Vacuoles synthesis typically contain a high number
of ribosomes.

11. If a substance is moving across Active Transport
a plasma membrane against
the concentration gradient, what
type of transport is required?

Passive transport
Active transport
Osmosis
Diffusion

12. The cell membrane is composed A bilayer of phospholipid molecules
of which of the following?

A single layer of phospholipid
molecules
A bilayer of phospholipid mole-
cules
A rigid layer of cytoskeleton
A wall of cholesterol and phos-
pholipids

13. Which organelle is responsible Mitochondria
for cellular respiration?
-Cellular respiration takes place inside
Golgi apparatus the mitochondria, which is the power-
Smooth endoplasmic reticulum house of the cell. In the mitochondria,
Mitochondria ATP (energy) is produced in three stages,
Rough endoplasmic reticulum which collectively are referred to as cellu-
lar respiration:

14. A metabolic pathway that breaks Cellular respiration
down glucose and produces
ATP is called __________.

Gluconeogenesis

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Human biology
Vak
Human biology

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