Pharmacology Final Exam Questions | High-Yield
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Frequently Most Tested Questions | Updated and
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1. Phenothiazines such as chlorpromazine are used to treat which condition?
A. Anxiety
B. Psychosis
C. Hypertension
D. Pain
✔ Correct Answer: B. Psychosis
Rationale:
Phenothiazines are first-generation antipsychotics that:
• Block dopamine (D2 receptors) in the brain
• Reduce hallucinations, delusions, and disorganized thinking
Key use: Schizophrenia and acute psychosis
Question 2: Alpha-1 Blockers
Alpha-1 blockers (e.g., tamsulosin) commonly cause which adverse effect?
A. Hypertension
B. Hypotension
C. Bradycardia
D. Hyperkalemia
✔ Correct Answer: B. Hypotension
Rationale:
A1 blockers:
, • Cause vasodilation
• Lower systemic vascular resistance
Result: Orthostatic hypotension (“first-dose effect”)
Nursing priority:
• Teach patient to change positions slowly
Question 3: Fever Reduction
Which medication reduces fever by acting on the hypothalamus?
A. Ibuprofen
B. Morphine
C. acetaminophen
D. Aspirin
✔ Correct Answer: C
Rationale:
Acetaminophen:
• Works on the hypothalamic heat-regulating center
• Lowers temperature without strong anti-inflammatory effect
Safer for patients with GI risk
Question 4: BPH Management
Which drug classes reduce symptoms of benign prostatic hyperplasia (BPH)?
✔ Correct Answer:
• Alpha-1 blockers (e.g., tamsulosin)
• 5-alpha reductase inhibitors (e.g., finasteride)
Rationale:
• A1 blockers → relax smooth muscle in prostate
• 5-AR inhibitors → shrink prostate over time
Combined therapy = better symptom control
,Question 5: Anxiety Medications
Benzodiazepines and antihistamines are used to reduce:
✔ Correct Answer: Anxiety
Rationale:
• Benzos (e.g., lorazepam) → enhance GABA → calming effect
• Antihistamines (e.g., diphenhydramine) → cause sedation
Both reduce CNS stimulation → ↓ anxiety
Question 6: Cholinergic Crisis
What are the key signs of a cholinergic crisis?
✔ Correct Answer:
• Bronchoconstriction
• Hypotension
• Diarrhea
• Circulatory collapse
• Bradycardia → cardiac arrest
Rationale:
Cholinergic crisis = excess acetylcholine
Think: “DUMBBELSS”
• Diarrhea
• Urination
• Miosis
• Bronchospasm
• Bradycardia
Priority: Airway (bronchoconstriction kills first)
, Question 7: Beta Blockers & Respiratory Risk
Why should non-selective beta blockers be avoided in asthma/COPD?
✔ Correct Answer: Bronchoconstriction
Rationale:
• Block B2 receptors in lungs
• Leads to airway narrowing
Dangerous → can trigger respiratory failure
Question 8: Antihistamines
hydroxyzine and diphenhydramine are classified as:
✔ Correct Answer: Antihistamines used to treat anxiety
Rationale:
• Cause sedation
• Used for:
o Anxiety
o Allergies
o Sleep
Question 9: Catecholamines
Name the three primary catecholamines.
✔ Correct Answer:
• Epinephrine
• Norepinephrine
• Dopamine
Rationale:
These are adrenergic neurotransmitters:
• Increase HR, BP, perfusion
Used in shock and cardiac emergencies
Questions & Answers| Well Rationalized and
Reviewed | 100% Guarantee Pass and Accurate |
Frequently Most Tested Questions | Updated and
Verified| Latest Exam and Newest Version!!!
1. Phenothiazines such as chlorpromazine are used to treat which condition?
A. Anxiety
B. Psychosis
C. Hypertension
D. Pain
✔ Correct Answer: B. Psychosis
Rationale:
Phenothiazines are first-generation antipsychotics that:
• Block dopamine (D2 receptors) in the brain
• Reduce hallucinations, delusions, and disorganized thinking
Key use: Schizophrenia and acute psychosis
Question 2: Alpha-1 Blockers
Alpha-1 blockers (e.g., tamsulosin) commonly cause which adverse effect?
A. Hypertension
B. Hypotension
C. Bradycardia
D. Hyperkalemia
✔ Correct Answer: B. Hypotension
Rationale:
A1 blockers:
, • Cause vasodilation
• Lower systemic vascular resistance
Result: Orthostatic hypotension (“first-dose effect”)
Nursing priority:
• Teach patient to change positions slowly
Question 3: Fever Reduction
Which medication reduces fever by acting on the hypothalamus?
A. Ibuprofen
B. Morphine
C. acetaminophen
D. Aspirin
✔ Correct Answer: C
Rationale:
Acetaminophen:
• Works on the hypothalamic heat-regulating center
• Lowers temperature without strong anti-inflammatory effect
Safer for patients with GI risk
Question 4: BPH Management
Which drug classes reduce symptoms of benign prostatic hyperplasia (BPH)?
✔ Correct Answer:
• Alpha-1 blockers (e.g., tamsulosin)
• 5-alpha reductase inhibitors (e.g., finasteride)
Rationale:
• A1 blockers → relax smooth muscle in prostate
• 5-AR inhibitors → shrink prostate over time
Combined therapy = better symptom control
,Question 5: Anxiety Medications
Benzodiazepines and antihistamines are used to reduce:
✔ Correct Answer: Anxiety
Rationale:
• Benzos (e.g., lorazepam) → enhance GABA → calming effect
• Antihistamines (e.g., diphenhydramine) → cause sedation
Both reduce CNS stimulation → ↓ anxiety
Question 6: Cholinergic Crisis
What are the key signs of a cholinergic crisis?
✔ Correct Answer:
• Bronchoconstriction
• Hypotension
• Diarrhea
• Circulatory collapse
• Bradycardia → cardiac arrest
Rationale:
Cholinergic crisis = excess acetylcholine
Think: “DUMBBELSS”
• Diarrhea
• Urination
• Miosis
• Bronchospasm
• Bradycardia
Priority: Airway (bronchoconstriction kills first)
, Question 7: Beta Blockers & Respiratory Risk
Why should non-selective beta blockers be avoided in asthma/COPD?
✔ Correct Answer: Bronchoconstriction
Rationale:
• Block B2 receptors in lungs
• Leads to airway narrowing
Dangerous → can trigger respiratory failure
Question 8: Antihistamines
hydroxyzine and diphenhydramine are classified as:
✔ Correct Answer: Antihistamines used to treat anxiety
Rationale:
• Cause sedation
• Used for:
o Anxiety
o Allergies
o Sleep
Question 9: Catecholamines
Name the three primary catecholamines.
✔ Correct Answer:
• Epinephrine
• Norepinephrine
• Dopamine
Rationale:
These are adrenergic neurotransmitters:
• Increase HR, BP, perfusion
Used in shock and cardiac emergencies
