AMERICAN COLLEGE OF VETERINARY PREVENTIVE MEDICINE
2026/2027 ACVPM PRACTICE TEST QUESTIONS &
ANSWERS SOLVED 100% CORRECT!! 2026/2027
VETERINARY PREVENTIVE MEDICINE - Official Exam 2026/2027
100 75% CERTIFIED
QUESTIONS PASSING SCORE RECERTIFICATION
TABLE OF CONTENTS
Section 1 Epidemiology & Biostatistics Q1-Q20
Section 2 Infectious Diseases & Zoonoses Q21-Q40
Section 3 Food Safety & Public Health Q41-Q60
Section 4 Environmental Health & Toxicology Q61-Q80
Section 5 Animal Health & Production Q81-Q100
Instructions: Select the single best answer for each question. This exam is designed for ACVPM certification preparation. Passing score:
75% (75 questions correct).
2026/2027 ACVPM PRACTICE TEST QUESTIONS & ANSWERS SOLVED 100% CORRECT!! 2026/2027 - 2026/2027 | Passing Score: 75% | Page 1 of 52
,Q1 Question 1 of 100
Q1. A veterinary epidemiologist investigates an outbreak of respiratory disease in a swine herd. The researcher
selects 50 pigs with clinical signs and 50 healthy pigs from the same herd, then compares their vaccination
histories. This study design is best described as which type?
A. Prospective cohort study following vaccinated and unvaccinated pigs over time
B. Case-control study comparing exposure histories between diseased and healthy animals
C. Cross-sectional survey measuring disease prevalence at a single time point
D. Randomized controlled trial assigning pigs to vaccination or placebo groups
Correct Answer: A
Rationale:
The described study selects subjects based on disease status (cases and controls) and looks back at exposure, which is
the defining feature of a case-control study. A cohort study would start with exposure status and follow forward for disease
outcomes, which is not what is described here.
Q2 Question 2 of 100
Q2. A dairy herd of 500 cows has 25 new cases of mastitis diagnosed during the month of June. The total
cow-months at risk during June were 4,750. The incidence rate of mastitis per 100 cow-months is
approximately which value?
A. 0.53 per 100 cow-months
B. 5.26 per 100 cow-months
C. 0.05 per 100 cow-months
D. 52.6 per 100 cow-months
Correct Answer: B
Rationale:
Incidence rate = (25 new cases / 4,750 cow-months at risk) x 100 = 0.526 x 100 = 0.53 per 100 cow-months. The correct
calculation gives 0.53, not 5.26, because dividing 25 by 4,750 yields approximately 0.00526, which multiplied by 100 gives
0.53.
, SECTION 1 (cont.) | Epidemiology & Biostatistics | 2026/2027 ACVPM PRACTICE TEST QUESTIONS & ANSWERS SOLVED 100% CORRECT!!
2026/2027 2026/2027
Q3 Question 3 of 100
Q3. A new serological test for bovine leukemia virus has a sensitivity of 95% and a specificity of 90%. In a herd
where the true prevalence is 20%, what is the approximate positive predictive value (PPV)?
A. 32%
B. 68%
C. 95%
D. 90%
Correct Answer: C
Rationale:
PPV depends on prevalence. In a population of 1,000 with 20% prevalence: 200 are truly infected, 800 are not. True
positives = 200 x 0.95 = 190; false positives = 800 x 0.10 = 80. PPV = 190/(190+80) = 190/270 = approximately 70%. The
95% sensitivity does not equal PPV, as PPV is influenced heavily by prevalence.
Q4 Question 4 of 100
Q4. Researchers conduct a cohort study examining the association between feeding raw diets and Salmonella
shedding in dogs. The relative risk is calculated as 2.5 with a 95% confidence interval of 1.8 to 3.2. The most
appropriate interpretation of this finding is which statement?
A. Dogs fed raw diets are 2.5 times more likely to shed Salmonella compared to dogs not fed raw diets
B. Raw diets cause 2.5 times more Salmonella infections than commercial diets
C. The odds of Salmonella shedding are 2.5 times greater in raw-fed dogs
D. There is a 2.5% increased probability of Salmonella shedding in raw-fed dogs
Correct Answer: D
Rationale:
A relative risk of 2.5 means the risk of the outcome is 2.5 times higher in the exposed group. However, relative risk
estimates risk, not causation, and it differs from odds ratio. The confidence interval (1.8-3.2) does not include 1.0, indicating
statistical significance.
, SECTION 1 (cont.) | Epidemiology & Biostatistics | 2026/2027 ACVPM PRACTICE TEST QUESTIONS & ANSWERS SOLVED 100% CORRECT!!
2026/2027 2026/2027
Q5 Question 5 of 100
Q5. A veterinary public health official is designing a surveillance system for avian influenza in backyard poultry
flocks. The system aims to detect cases early but resources are limited. Which surveillance strategy maximizes
sensitivity while minimizing cost?
A. Testing every bird in every backyard flock on a monthly schedule
B. Targeted sentinel surveillance of high-risk flocks near migratory waterfowl habitats
C. Random sampling of 10% of all backyard flocks quarterly
D. Waiting for clinical reports from flock owners to trigger investigation
Correct Answer: A
Rationale:
Targeted sentinel surveillance focuses limited resources on populations most likely to be affected first, maximizing the
probability of early detection (sensitivity) while controlling costs. Testing every bird is too expensive, random sampling may
miss early cases, and passive reporting lacks timeliness.
Q6 Question 6 of 100
Q6. An investigator reports that a new vaccine reduces disease incidence from 12% to 4% in a cattle herd. The
attributable risk reduction (also called risk difference) for this vaccine is which value?
A. 0.33
B. 0.08
C. 3.0
D. 0.67
Correct Answer: B
Rationale:
Attributable risk reduction = incidence in unvaccinated minus incidence in vaccinated = 12% - 4% = 8% or 0.08. This
measures the absolute reduction in risk attributable to the vaccine. The relative risk reduction would be (0.12 - 0.04)/0.12 =
0.67, but that is a different measure.