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ATI CMS Fundamentals 2026 – 150+ Nursing Fundamentals, Pharmacology, Diabetes, Cardiovascular Care, Respiratory Disorders, Fluid & Electrolyte Balance & NCLEX-Style Questions and Answers

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This comprehensive ATI CMS Fundamentals 2026 study guide contains more than 150 detailed NCLEX-style questions and verified answers covering nursing fundamentals, pharmacology, medication administration, diabetes management, cardiovascular nursing, respiratory disorders, infection control, acid-base balance, fluid and electrolyte regulation, postoperative care, musculoskeletal disorders, HIV/AIDS care, oncology nursing, emergency nursing, and patient safety principles. The document provides extensive review material on clinical decision-making, prioritization, nursing interventions, laboratory interpretation, medication safety, and evidence-based patient care concepts frequently tested on ATI CMS Fundamentals examinations and nursing school assessments. The material is organized in a structured question-and-answer format specifically designed to strengthen understanding of foundational nursing concepts and improve examination readiness. Major topics include medication administration, insulin therapy, hypoglycemia and hyperglycemia management, oral antidiabetic medications, anticoagulants, antihypertensive medications, cardiac drugs, respiratory medications, HIV pharmacotherapy, tuberculosis treatment, and safe medication teaching. Detailed explanations review lispro insulin, NPH insulin, metformin, glipizide, warfarin, heparin, furosemide, propranolol, atorvastatin, digoxin, lisinopril, rifampin, albuterol, salmeterol, and other medications commonly encountered in nursing practice and NCLEX-style examinations. Extensive cardiovascular and respiratory nursing content examines hypertension, heart failure, myocardial infarction, angina pectoris, pacemakers, deep vein thrombosis (DVT), pulmonary embolism, shock states, COPD, asthma, pneumonia, tuberculosis, obstructive sleep apnea, respiratory acidosis, respiratory alkalosis, oxygen therapy, pulse oximetry interpretation, arterial blood gas (ABG) analysis, and airway management. Students review priority interventions, emergency response strategies, oxygenation principles, cardiac monitoring, and evidence-based nursing care for acute and chronic cardiopulmonary disorders. The guide also provides comprehensive coverage of fluid, electrolyte, and acid-base disorders including metabolic alkalosis, respiratory acidosis, respiratory alkalosis, metabolic acidosis, hyponatremia, potassium regulation, hypovolemic shock, septic shock, disseminated intravascular coagulation (DIC), and fluid replacement therapy. Additional sections review laboratory value interpretation, arterial blood gas analysis, electrolyte monitoring, coagulation studies, and clinical manifestations associated with common metabolic disturbances encountered in nursing practice. A substantial portion of the study material focuses on adult health nursing and chronic disease management. Topics include diabetes mellitus, osteoporosis, osteoarthritis, rheumatoid arthritis, compartment syndrome, amputation care, cancer treatment, chemotherapy complications, HIV/AIDS management, burns, wound care, immobility complications, renal disease, vascular disorders, fracture healing, inflammatory responses, and infection prevention. Students gain practical knowledge of nursing assessments, patient education, therapeutic interventions, and discharge planning considerations across a wide range of medical-surgical conditions. The study guide further explores nursing fundamentals such as medical and surgical asepsis, patient assessment, pain management, postoperative care, prioritization frameworks, patient teaching, communication techniques, safety measures, mobility promotion, tracheostomy care, suctioning, fall prevention, and long-term care management. Numerous dosage calculations, clinical judgment scenarios, laboratory interpretation questions, and priority-setting exercises provide valuable preparation for ATI CMS Fundamentals testing, nursing program examinations, and NCLEX-RN success. This resource is highly beneficial for Associate Degree Nursing (ADN) students, Bachelor of Science in Nursing (BSN) students, Practical Nursing (PN/LPN) students, Registered Nurse (RN) candidates, ATI testing candidates, NCLEX-RN candidates, nursing fundamentals students, medical-surgical nursing students, healthcare students, and prelicensure nursing students preparing for ATI CMS Fundamentals examinations, nursing school assessments, clinical rotations, HESI testing, and nursing licensure preparation. It is especially useful for students seeking mastery of core nursing concepts, pharmacology, patient safety, and clinical judgment skills. The study material aligns with evidence-based nursing education standards outlined in ATI Nursing Education, Potter & Perry's Fundamentals of Nursing, Taylor's Clinical Nursing Skills, Lehne's Pharmacology for Nursing Care, Ignatavicius Medical-Surgical Nursing, Brunner & Suddarth's Textbook of Medical-Surgical Nursing, and the NCLEX-RN Test Plan published by the National Council of State Boards of Nursing (NCSBN). Concepts involving medication administration, cardiovascular care, respiratory management, infection prevention, fluid and electrolyte balance, and chronic disease management are additionally supported by standards from the American Nurses Association (ANA), Centers for Disease Control and Prevention (CDC), and contemporary nursing education curricula. Keywords ATI CMS Fundamentals 2026, ATI Fundamentals Exam, ATI CMS nursing exam, NCLEX RN preparation, nursing fundamentals, nursing exam questions, nursing study guide, pharmacology, medication administration, insulin therapy, lispro insulin, NPH insulin, metformin, glipizide, warfarin, heparin, digoxin, atorvastatin, lisinopril, rifampin, furosemide, propranolol, diabetes mellitus, hypoglycemia, hyperglycemia, diabetic ketoacidosis, cardiovascular nursing, heart failure, myocardial infarction, angina, pacemaker care, DVT, pulmonary embolism, hypertension, respiratory disorders, COPD, asthma, pneumonia, tuberculosis, oxygen therapy, pulse oximetry, arterial blood gases, ABG interpretation, respiratory acidosis, respiratory alkalosis, metabolic alkalosis, metabolic acidosis, fluid and electrolyte balance, hyponatremia, potassium levels, shock management, septic shock, hypovolemic shock, DIC, infection control, asepsis, postoperative nursing care, pain assessment, patient education, tracheostomy care, suctioning, HIV nursing care, oncology nursing, chemotherapy complications, burns, osteoporosis, osteoarthritis, rheumatoid arthritis, compartment syndrome, fracture healing, renal disease, immobility complications, nursing calculations, dosage calculations, patient safety, clinical judgment, prioritization, ATI review, HESI preparation, RN licensure exam, nursing school notes, medical surgical nursing, healthcare education, NCLEX style questions

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CMS Fundamentals 2026 Exam
Questions with 100% Correct
Answers | Latest Update



A nurse administers subcutaneous lispro insulin at 0700 to a client who

has diabetes. At which of the following times should the nurse observe

for hypoglycemia caused by the onset of the medication? - ANSWER

✔✔0715


What is required by medical asepsis that is not required by surgical

asepsis? - ANSWER ✔✔good hand washing technique


A nurse is preparing to administer dexamethasone 1.5 mg/kg/day PO to

divide equally every 6 hours to a preschool-age child who weighs 22 lb.

,Available is dexamethasone oral solution 1 mg/mL. How many mL

should the nurse administer per dose? (Round the answer to the nearest

tenth.) - ANSWER ✔✔3.8


A postoperative client who has no previous medical conditions is difficult

to arouse when transferred to the surgical unit from the post-anesthesia

care unit. A nurse monitors the pulse oximeter and gets a reading of

85%. The nurse arouses the client and has him cough and perform deep

breathing; the pulse oximeter is now reading 83% what should be the

nurse's next action? - ANSWER ✔✔Start oxygen at 2 liters per nasal

cannula.

A nurse in the emergency department knows that tissue damage has

probably occurred in a person with hypothermia when a rectal

temperature of _____ is assessed. (do not use degree sign,) -

ANSWER ✔✔95


At 0330, a nurse is caring for a client who is postoperative. The client's

IV fluids are infusing at 120 mL/hr. How many mL of IV fluid should

infuse by 0600? (Round the answer to the nearest whole number. Use a

leading zero if it applies. Do not use a trailing zero.) - ANSWER

✔✔300

, A nurse is reinforcing teaching with a client who has a family history of

hypertension. The nurse should inform the client that his blood pressure

reading of 112/64 mm Hg places him in which of the following

categories? - ANSWER ✔✔Within the expected reference range


A nurse is reinforcing teaching with a client who has type 2 diabetes

mellitus. The nurse determines that teaching has been effective when

the client identifies which of the following manifestations of

hypoglycemia? (Select all that apply.) - ANSWER ✔✔-Blurry vision


-tachycardia

-sweating

A nurse is reinforcing teaching with a client who has diabetes mellitus

and self-administers insulin. The client reports drinking an occasional

glass of wine. Which of the following is an appropriate response by the

nurse? - ANSWER ✔✔"It is best for you to drink an occasional glass

of wine with a meal".

A nurse is caring for a client who has type 1 diabetes mellitus. The nurse

misread the client's morning fasting blood glucose level as 210 mg/dL

instead of 120 mg/dL and administered the insulin dose appropriate for a

reading over 200 mg/dL. Which of the following actions should the nurse




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