1|Page
GEORGETTE PMHNP REVIEW | VERIFIED
STUDY GUIDE WITH QUESTIONS & ANSWERS
FOR PSYCHIATRIC-MENTAL HEALTH NURSE
PRACTITIONER 2026
If your patient is a smoker you will need ___________doses of their medication. -
correct-answer -higher
Inhibitors - correct-answer -inhibit metabolism and therefore increase levels of
the drug.
SICKFACES.com for Inhibitors - correct-answer -Sodium valproate
Isoniazid
Cimetidine
Ketoconazole
Alcohol
Chloramphenicol
Erythromycin
Sulfonamine
Cipro
Omeprazole
Metronidazole
,2|Page
Which cytochrome enzyme is implicated as a tobacco inducer when an individual
is treated with clozapine
a. 2D6
b. 1A2
c. 2C19
d. 2C9 - correct-answer -1A2
(want A 2 cigarette break)
When treating older adults, you should keep in mind that they are more sensitive
to issues of drug toxicity because of which of the following reasons?
A. Decreased body fat
B. Increased liver capacity
C. Decreased protein binding
D. Increased muscle concentration - correct-answer -Decreased protein binding
For 12 years, a 65 year old patient with bipolar affective disorder has been
treated with lithium 900 mg daily. When oral HCTC 12.5 daily is added for
hypertension, the patient develops nausea, vomiting, ataxia, and muscle
weakness and the patient's serum lithium level is 2.0. The interaction of the
lithium and the thiazide diuretic has induced:
A. hypokalemia
B. hyponatremia
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C. Increased renal clearance of lithium
D. Decreased renal clearance of lithium - correct-answer -A. decreased renal
clearance of lithium
Where is norepinephrine produced - correct-answer -locus coeruleus and
medullary reticular formation
Norepinephrine is associated with - correct-answer -mood disorders
Serotonin is made where in the brain - correct-answer -raphe nuclei of the
brainsteam
Serotonin is associated with - correct-answer -sleep and mood disorder
Dopamine is made in - correct-answer -substantia nigra, central tegmental area,
ventral tegmental area,
Dopamine is associated with - correct-answer -addiction and psychosis
, 4|Page
Acetylcholine is made - correct-answer -basal nucleus of Meynert
Most abundant inhibitory neurotransmitter in the brain - correct-answer -GABA
I don't have enough GABA, my anxiety is high
Med used to increase GABA - correct-answer -benzos
Fred flinstone needs a Zanny, Gabba dabba do.
Most excitatory neutransmitter - correct-answer -glutamate
Increased level of corticotropin releasing hormone in the amygdala, hippocampus
and locus coeruleus - correct-answer -increases symptoms of anxiety.
Autism - correct-answer -deficits in social communication and social interaction
across multiple settings
Parents of kids with autism may report - correct-answer -No response when
called by name
Little or no eye contact
GEORGETTE PMHNP REVIEW | VERIFIED
STUDY GUIDE WITH QUESTIONS & ANSWERS
FOR PSYCHIATRIC-MENTAL HEALTH NURSE
PRACTITIONER 2026
If your patient is a smoker you will need ___________doses of their medication. -
correct-answer -higher
Inhibitors - correct-answer -inhibit metabolism and therefore increase levels of
the drug.
SICKFACES.com for Inhibitors - correct-answer -Sodium valproate
Isoniazid
Cimetidine
Ketoconazole
Alcohol
Chloramphenicol
Erythromycin
Sulfonamine
Cipro
Omeprazole
Metronidazole
,2|Page
Which cytochrome enzyme is implicated as a tobacco inducer when an individual
is treated with clozapine
a. 2D6
b. 1A2
c. 2C19
d. 2C9 - correct-answer -1A2
(want A 2 cigarette break)
When treating older adults, you should keep in mind that they are more sensitive
to issues of drug toxicity because of which of the following reasons?
A. Decreased body fat
B. Increased liver capacity
C. Decreased protein binding
D. Increased muscle concentration - correct-answer -Decreased protein binding
For 12 years, a 65 year old patient with bipolar affective disorder has been
treated with lithium 900 mg daily. When oral HCTC 12.5 daily is added for
hypertension, the patient develops nausea, vomiting, ataxia, and muscle
weakness and the patient's serum lithium level is 2.0. The interaction of the
lithium and the thiazide diuretic has induced:
A. hypokalemia
B. hyponatremia
,3|Page
C. Increased renal clearance of lithium
D. Decreased renal clearance of lithium - correct-answer -A. decreased renal
clearance of lithium
Where is norepinephrine produced - correct-answer -locus coeruleus and
medullary reticular formation
Norepinephrine is associated with - correct-answer -mood disorders
Serotonin is made where in the brain - correct-answer -raphe nuclei of the
brainsteam
Serotonin is associated with - correct-answer -sleep and mood disorder
Dopamine is made in - correct-answer -substantia nigra, central tegmental area,
ventral tegmental area,
Dopamine is associated with - correct-answer -addiction and psychosis
, 4|Page
Acetylcholine is made - correct-answer -basal nucleus of Meynert
Most abundant inhibitory neurotransmitter in the brain - correct-answer -GABA
I don't have enough GABA, my anxiety is high
Med used to increase GABA - correct-answer -benzos
Fred flinstone needs a Zanny, Gabba dabba do.
Most excitatory neutransmitter - correct-answer -glutamate
Increased level of corticotropin releasing hormone in the amygdala, hippocampus
and locus coeruleus - correct-answer -increases symptoms of anxiety.
Autism - correct-answer -deficits in social communication and social interaction
across multiple settings
Parents of kids with autism may report - correct-answer -No response when
called by name
Little or no eye contact
