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Comprehensive HESI RN Pharmacology Practice Exam Study
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THIS EXAM CONTAINS:
• Cardiovascular medications and nursing interventions
• Antibiotics, antivirals, and anti-infective drugs
• Endocrine and diabetic medication management
• Pain management, opioids, and non-opioid analgesics
• Psychiatric and neurological medications
• Respiratory, gastrointestinal, and renal pharmacology
• Dosage calculations and medication administration safety
• Comprehensive exam review notes and pharmacology study guide
• Updated 2026–2027 HESI RN Pharmacology exam preparation
materials with complete solutions
,HESI RN Pharmacology Exam
1. Following the administration of sublingual nitroglycerin to a client experiencing
an acute anginal attack, which assessment finding indicates to the nurse that the
desired effect has been achieved?
A. Client's blood pressure increases to 130/80 mmHg
B. Client states chest pain is relieved
C. Client's heart rate decreases to 60 bpm
D. Client reports headache relief
Answer: B
2. Following heparin treatment for a pulmonary embolism, a client is being
discharged with a prescription for warfarin (Coumadin). In conducting discharge
teaching, the nurse advises the client to have which diagnostic test monitored
regularly after discharge?
A. Complete blood count (CBC)
B. Activated partial thromboplastin time (aPTT)
C. Prothrombin Time (PT/INR)
D. Platelet count
Answer: C
3. A healthcare provider prescribes cephalexin monohydrate (Keflex) for a client
with a postoperative infection. It is most important for the nurse to assess for
what additional drug allergy before administering this prescription?
A. Sulfonamides
, B. Tetracyclines
C. Penicillin
D. Macrolides
Answer: C
4. A client is admitted to the coronary care unit with a medical diagnosis of acute
myocardial infarction. Which medication prescription decreases both preload and
afterload?
A. Digoxin
B. Nitroglycerin
C. Metoprolol
D. Furosemide
Answer: B
5. Which dosing schedule should the nurse teach the client to observe for a
controlled-release oxycodone prescription?
A. Every 4 hours
B. Every 6 hours
C. Every 8 hours
D. Every 12 hours
Answer: D