PN PHARMACOLOGY ATI PROCTORED EXAM PRACTICE
80+ Original NGN-Style Questions with Answers & Rationales|
Advanced Pathophysiology NURS 5315 Comprehensive Examination
– Full 180-Question Practice Test with Evidence-Based Rationales
(Latest 2026 Update)
A practical nurse is preparing to administer medications to a client.
Which action should the nurse take FIRST to ensure medication
safety?
A) Verify the client's identity using two identifiers
B) Check the medication expiration date
C) Review the client's allergy history
D) Confirm the medication order with the provider
✅ ✔Correct Answer: A) Verify the client's identity using two
identifiers
Rationale: The first step in the medication administration process is
confirming the right patient using two unique identifiers (e.g., name
and date of birth) per the "Rights of Medication Administration"
,. While all options are important safety steps, patient identification is
the foundational action that must occur before any other verification
to prevent administering medications to the wrong client.
Question 2 (NGN: Bow-Tie Format)
Scenario: A client is prescribed enoxaparin 40 mg subcutaneously
daily for DVT prophylaxis.
Prioritize
Recogniz Analyze Generate Take Evaluate
Hypothese
e Cues Cues Solutions Action Outcomes
s
Client
Use Administe
reports Enoxaparin Monitor for
proper r in
bruising is an Risk for signs of
injection abdomen,
at anticoagulan bleeding hemorrhag
techniqu do not rub
injection t e
e site
site
Question: Which action should the PN take when administering
enoxaparin to minimize complications? (Select all that apply)
,A) Massage the injection site after administration
B) Pinch the skin and inject at a 90-degree angle
C) Rotate injection sites with each dose
D) Aspirate before injecting the medication
E) Apply firm pressure for 1-2 minutes after injection
✅ ✔Correct Answers: B, C, E
Rationale:
✅ B: Enoxaparin should be injected subcutaneously at a 90-
degree angle with a pinched skin fold to ensure proper
absorption
www.myamericannurse.com
✅ C: Site rotation prevents tissue irritation and lipodystrophy
✅ E: Applying pressure (without rubbing) minimizes bruising
and hematoma formation
❌ A: Massaging the site increases absorption rate and risk of
bruising with anticoagulants
, ❌ D: Aspiration is not recommended for subcutaneous
injections as it can cause tissue trauma
Question 3 (NGN: Matrix/Grid)
A PN is reviewing medications for a client with multiple
prescriptions. Match each medication to its primary nursing
consideration:
Avoid Check Apical
Monitor for Administer
Medication Grapefruit Pulse Before
Hypokalemia with Food
Juice Administering
Furosemide ☑ ☐ ☐ ☐
Digoxin ☐ ☐ ☑ ☑
Atorvastatin ☐ ☐ ☑ ☐
Metformin ☐ ☑ ☐ ☐
✅ Correct Selections as shown above
Rationale:
80+ Original NGN-Style Questions with Answers & Rationales|
Advanced Pathophysiology NURS 5315 Comprehensive Examination
– Full 180-Question Practice Test with Evidence-Based Rationales
(Latest 2026 Update)
A practical nurse is preparing to administer medications to a client.
Which action should the nurse take FIRST to ensure medication
safety?
A) Verify the client's identity using two identifiers
B) Check the medication expiration date
C) Review the client's allergy history
D) Confirm the medication order with the provider
✅ ✔Correct Answer: A) Verify the client's identity using two
identifiers
Rationale: The first step in the medication administration process is
confirming the right patient using two unique identifiers (e.g., name
and date of birth) per the "Rights of Medication Administration"
,. While all options are important safety steps, patient identification is
the foundational action that must occur before any other verification
to prevent administering medications to the wrong client.
Question 2 (NGN: Bow-Tie Format)
Scenario: A client is prescribed enoxaparin 40 mg subcutaneously
daily for DVT prophylaxis.
Prioritize
Recogniz Analyze Generate Take Evaluate
Hypothese
e Cues Cues Solutions Action Outcomes
s
Client
Use Administe
reports Enoxaparin Monitor for
proper r in
bruising is an Risk for signs of
injection abdomen,
at anticoagulan bleeding hemorrhag
techniqu do not rub
injection t e
e site
site
Question: Which action should the PN take when administering
enoxaparin to minimize complications? (Select all that apply)
,A) Massage the injection site after administration
B) Pinch the skin and inject at a 90-degree angle
C) Rotate injection sites with each dose
D) Aspirate before injecting the medication
E) Apply firm pressure for 1-2 minutes after injection
✅ ✔Correct Answers: B, C, E
Rationale:
✅ B: Enoxaparin should be injected subcutaneously at a 90-
degree angle with a pinched skin fold to ensure proper
absorption
www.myamericannurse.com
✅ C: Site rotation prevents tissue irritation and lipodystrophy
✅ E: Applying pressure (without rubbing) minimizes bruising
and hematoma formation
❌ A: Massaging the site increases absorption rate and risk of
bruising with anticoagulants
, ❌ D: Aspiration is not recommended for subcutaneous
injections as it can cause tissue trauma
Question 3 (NGN: Matrix/Grid)
A PN is reviewing medications for a client with multiple
prescriptions. Match each medication to its primary nursing
consideration:
Avoid Check Apical
Monitor for Administer
Medication Grapefruit Pulse Before
Hypokalemia with Food
Juice Administering
Furosemide ☑ ☐ ☐ ☐
Digoxin ☐ ☐ ☑ ☑
Atorvastatin ☐ ☐ ☑ ☐
Metformin ☐ ☑ ☐ ☐
✅ Correct Selections as shown above
Rationale:
