CMN 577 UNIT 3 BIOTERROISM MCPHEE QUESTIONS
& VERIFIED ANSWERS
What are the 3 forms of naturally occurring Botulism? - Answers - 1. food borne
2. Infant (ingested honey)
3. Wound (injection drug use)
What are the s/s of ingested Botulism? (4) - Answers - -12-36 hours after ingestion,
*visual disturbances (diplopia and loss of accomodation)*
-*Ptosis*
-*Cranial nerve palsies with impairment of ocular muscles, fixed dilated pupils*
-Sensory exam is normal
-dry mouth, dysphagia, dysphonia
-N/V Type E toxin
-Sensorium clear, temperature normal
-*Paralysis progresses to respiratory failure*
What is the treatment for Botulism? (1) When is this ideally administered? Do you delay
treatment until lab confirmation? - Answers - -Contact state health or CDC for advice
-Equine Serum heptavalent botulism antitoxin
-Ideally within 24 hours of onset of s/s to arrest progression
-DO NOT delay administration for lab confirmation
-may remove unabsorbed toxin from gut, assay for toxin
How do you catch Anthrax? (6) - Answers - -exposure to animals or animal hides
(sheep, cattle, horses, goats, swine)
-through soil by inoculation of broken skin or mm
-inhalation of aerosolized spores
-ingestion resulting in cutaneous, inhalational or GI forms of anthrax
-act of bioterrorism
-has been sent through the mail
What are the s/s of cutaneous Anthrax? (5) - Answers - *-occurs within 2 weeks after
exposure to spores
-no latency period
-initial lesion is erythematous papule that vesiculates then ulcerates and undergoes
necrosis, progressing to purple to black eschar
-eschar is painless, but pain indicates secondary step or strep infection*
-surrounding area is edematous and vesicular but not purulent
-regional adenopathy,fever, malaise H/A, , N/V
-*usually self limiting, but can spread to sepsis or meningitis*
& VERIFIED ANSWERS
What are the 3 forms of naturally occurring Botulism? - Answers - 1. food borne
2. Infant (ingested honey)
3. Wound (injection drug use)
What are the s/s of ingested Botulism? (4) - Answers - -12-36 hours after ingestion,
*visual disturbances (diplopia and loss of accomodation)*
-*Ptosis*
-*Cranial nerve palsies with impairment of ocular muscles, fixed dilated pupils*
-Sensory exam is normal
-dry mouth, dysphagia, dysphonia
-N/V Type E toxin
-Sensorium clear, temperature normal
-*Paralysis progresses to respiratory failure*
What is the treatment for Botulism? (1) When is this ideally administered? Do you delay
treatment until lab confirmation? - Answers - -Contact state health or CDC for advice
-Equine Serum heptavalent botulism antitoxin
-Ideally within 24 hours of onset of s/s to arrest progression
-DO NOT delay administration for lab confirmation
-may remove unabsorbed toxin from gut, assay for toxin
How do you catch Anthrax? (6) - Answers - -exposure to animals or animal hides
(sheep, cattle, horses, goats, swine)
-through soil by inoculation of broken skin or mm
-inhalation of aerosolized spores
-ingestion resulting in cutaneous, inhalational or GI forms of anthrax
-act of bioterrorism
-has been sent through the mail
What are the s/s of cutaneous Anthrax? (5) - Answers - *-occurs within 2 weeks after
exposure to spores
-no latency period
-initial lesion is erythematous papule that vesiculates then ulcerates and undergoes
necrosis, progressing to purple to black eschar
-eschar is painless, but pain indicates secondary step or strep infection*
-surrounding area is edematous and vesicular but not purulent
-regional adenopathy,fever, malaise H/A, , N/V
-*usually self limiting, but can spread to sepsis or meningitis*
