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PHARMACOLOGY HESI NCLEX REVIEW 2026 COMPLETE WITH PRACTICE QUESTIONS AND VERIFIED ANSWERS

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Prepare confidently for nursing, HESI, and NCLEX examinations with this comprehensive 2026 Pharmacology review featuring real exam-style practice questions, verified answers, and detailed rationales designed to strengthen understanding of drug classifications, medication safety, and clinical judgment. Ideal for nursing students and graduates preparing for licensure and exit exams, this complete study guide helps reinforce essential pharmacology concepts, improve exam readiness, boost confidence, and support success across HESI and NCLEX examinations.

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PHARMACOLOGY HESI NCLEX REVIEW
2026 COMPLETE REVIEW WITH
PRACTICE QUESTIONS AND VERIFIED
ANSWERS| GRADED A+ | GUARANTEED
SUCCESS
Updated 2026 Questions and Answers | 100% Verified
Exam Prep and Comprehensive Rationales Included

,1. A male client who has been taking a high dose of a C
nonsteroidal anti inflammatory drug (NSAID) comes to
the clinic complaining of gastric pain and blood in his
stool. The healthcare provider discontinues the NSAIDs
and prescribes esomeprazole. Which information should
the client include in the nurse’s teaching plan?
A. Once pain subsides, NSAID therapy can be continued
B. Resume a diet that consists of milk, cream, and bland
foods
C. Notify the healthcare provider of the passage of black
stool
D. Call the clinic if diarrhea or headache occur when
taking esomeprazole


2. When administering zolpidem to an older client, which A
computer documentation indicates that the desired
outcome has been achieved?
A. Sleeps soundly through the night
B. Decreased episodes of incontinence
C. Exhibits fewer emotional outburst
D. Improved ability to concentrate

,3. A male client with a fungal infection of the toenail A
reports to the nurse that he has been applying an over-
the-counter triple antibiotic ointment to the infection
daily for two weeks without any improvement.
Which action should the nurse take?
A. Instruct the client to obtain a prescription for oral
terbinafine
B. Suggest that the client use the ointment twice a day to
be more effective
C. Reassure that the treatment of fungus-infected toenails
often takes several months
D. Advise the client to obtain a prescription-strength
formulation of the ointment


A client with a nasogastric tube (NGT) has a prescription A
for sucralfate. The liquid form of the medication is not
currently available in the pharmacy and tablets have
been delivered to the medication
dispensing system. Which action should the nurse include
when administering the medication?
A. Crush the tablet and mix it with water separately from
other medications
B. Crush the tablet and mix it with other crushed tablets
diluted in water
C. Withhold the medication until a liquid form is available
on the nursing unit
D. Crush the tablet and mix it with other liquid
medications for administration


A client with chronic asthma receives a prescription for
montelukast, a leukotriene modifier. Which statement by
the client indicates to the nurse that medication teaching
was effective?
A. I should take this medication only when I am having an
asthma attack
B. I will take the tablet every evening to control my
asthma
C. This medication will stop an asthma attack immediately
D. I will not need to use my inhalers twice a day when I
start this medication


The nurse is planning to administer the antiulcer GI agent B
sucralfate to a client with peptic ulcer disease. Which
action should the nurse include in this client’s plan of
care?
A. Assess for secondary Candida infection
B. Administer sucralfate once a day, preferably at bedtime
C. Give sucralfate on an empty stomach
D. Monitor for electrolyte imbalance

, A client with anemia secondary to chronic kidney disease D
(CKD) started a prescription for epoetin alfa two months
ago. Which client finding best indicates that the
medication is effective?
A. Reports of increased energy levels and decreased
fatigue
B. Takes concurrent iron therapy without adverse effects
C. Food diary shows increased consumption of iron-rich
foods
D. Hemoglobin level increased to 12 grams/dL(120
mmol/L)


The healthcare provider prescribes propylthiouracil (PTU) B
and Lugol’s solution, a strong idoine solution, for a client
with hyperthyroidism. How should the nurse schedule the
administration of these medications?
A. Administer iodine one hour before PTU
B. Offer both drugs together with a meal
C. Schedule both medications at bedtime
D. Give parental dose once every 24 hours


Twenty minutes after the nurse starts a secondary IV A
infusion of cefepime 2 grams using an infusion pump to
deliver the dose in one hour, the client reports feeling
nauseated. Which action should the nurse implement?
A. Continue the infusion and administer a PRN antiemetic
prescription
B. Stop the medication infusion and notify the healthcare
provider of the adverse effect
C. Reassure the client that the nausea us not related to
the IV infusion
D. Increase the rate of the infusion to complete the dose
of the medication more rapidly


A client with diabetic peripheral neuropathy, who has A
been taking pregabalin for 2 weeks reports diminished
foot pain. The nurse notes that there is no improvement in
the healing of several toe ulcerations. Which action
should the nurse take?
A. Review the plan of care for strategies used to manage
the foot ulcerations
B. Reassure the client that diabetic foot ulcers take
several months to heal
C. Explain that the medication dosage will probably need
to be increased
D. Withhold the next dose of the drug until the healthcare
provider is notified

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