GENERAL BIOLOGY
Chapters 1–7 Midterm Study Guide
60 Questions with Correct Answers and Rationales
Aligned with Campbell Biology, OpenStax Biology, and Mader's Biology
BSC 1005 General Biology Midterm Study Guide | Page 1
,Table of Contents
Table of Contents .................................................................................................................................. 2
Introduction ........................................................................................................................................... 3
Section I: Scientific Inquiry and the Scientific Method ..................................................................... 3
Section II: Chemistry of Life ............................................................................................................... 6
Section III: Cell Structure and Function ............................................................................................ 9
Section IV: Cellular Energy and Metabolism .................................................................................. 12
Section V: Cell Division and Genetics Basics ................................................................................... 15
Section VI: DNA Structure and Protein Synthesis .......................................................................... 17
Section VII: Evolution and Ecology Foundations ............................................................................ 20
Quick-Reference Answer Key ............................................................................................................ 23
References ............................................................................................................................................ 25
Table of Contents .................................................................................................................................. 2
Introduction ........................................................................................................................................... 3
Section I: Scientific Inquiry and the Scientific Method ..................................................................... 3
Section II: Chemistry of Life ............................................................................................................... 6
Section III: Cell Structure and Function ............................................................................................ 9
Section IV: Cellular Energy and Metabolism .................................................................................. 12
Section V: Cell Division and Genetics Basics ................................................................................... 15
Section VI: DNA Structure and Protein Synthesis .......................................................................... 17
Section VII: Evolution and Ecology Foundations ............................................................................ 20
Quick-Reference Answer Key ............................................................................................................ 23
References ............................................................................................................................................ 25
BSC 1005 General Biology Midterm Study Guide | Page 2
, Introduction
This study guide is designed as a comprehensive midterm preparation resource for students
enrolled in BSC 1005 General Biology, covering Chapters 1 through 7. The 60 multiple-choice
questions are distributed across seven core content domains that reflect the standard scope and
sequence of introductory biology curricula at accredited institutions. Each question is accompanied by
the correct answer—highlighted in bold cyan—and a detailed rationale grounded in evidence-based
biological principles and aligned with widely adopted textbook references including Campbell
Biology (12th Edition), OpenStax Biology 2e, and Mader’s Biology (16th Edition).
The content domains addressed in this guide include: the scientific method and experimental
design, the chemistry of life (atomic structure, bonding, water properties, organic macromolecules),
cell structure and function (prokaryotic vs. eukaryotic organization, organelle systems, membrane
transport), cellular energy and metabolism (enzyme function, photosynthesis, cellular respiration), cell
division and genetics (the cell cycle, mitosis, meiosis, Mendelian inheritance), DNA structure and
protein synthesis (replication, transcription, translation), and evolution and ecology foundations
(natural selection, adaptation, ecosystem dynamics, biogeochemical cycles). Students are encouraged
to use this guide as a self-assessment tool, working through each section systematically and reviewing
the rationales for both correct and incorrect answer choices.
Content Domain Questions Approx. Weight
Scientific Inquiry & Method 1–9 15%
Chemistry of Life 10–18 15%
Cell Structure & Function 19–27 15%
Cellular Energy & Metabolism 28–36 15%
Cell Division & Genetics 37–44 13%
DNA & Protein Synthesis 45–52 13%
Evolution & Ecology 53–60 14%
Section I: Scientific Inquiry and the Scientific
Method
This section evaluates understanding of the scientific method, hypothesis formation, experimental
design, variable identification (independent, dependent, controlled), data interpretation, and the role of
peer review in advancing scientific knowledge.
BSC 1005 General Biology Midterm Study Guide | Page 3