AAMC MCAT PRACTICE EXAM 1
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PRACTICE QUESTIONS AND VERIFIED
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Updated 2026 Questions and Answers | 100% Verified
Exam Prep and Comprehensive Rationales Included
,According to the developed chromatography plate The answer to this question is A (0.20) because Rf is the ratio of the distance
shown below, what is the approximate Rf value of travelled by the analyte relative to the solvent front during a chromatographic
aspartic acid? separation. Aspartic acid travelled two units, while the solvent front travelled ten
units, giving an Rf of 2/10 = 0.20 for aspartic acid.
aspartic acid = 2
solvent front = 10
A) 0.20
B) 0.50
C) 5
D) 10
Which of the following statements does NOT correctly D) The reaction is stereospecific.
describe the dehydration of malic acid to fumaric acid
and maleic acid? The answer to this question is D because the fact that both fumaric and maleic
acid are produced means that the dehydration of malic acid is NOT stereospecific.
A) The reaction occurs most readily with tertiary alcohols.
B) The reaction involves the loss of a water molecule.
C) The reaction has a carbocation intermediate.
D) The reaction is stereospecific.
What type of functional group is formed when aspartic C) An amide group
acid reacts with another amino acid to form a peptide
bond? The answer to this question is C because the functional group that forms during
peptide bond formation is known as an amide group.
A) An amine group
B) An aldehyde group
C) An amide group
D) A carboxyl group
If 2-pentanol replaces 1-pentanol in the reaction shown in D) there is more steric hindrance at the 2-position of 2-pentanol than at the 1-
Figure 3 (SN2), the rate of substitution is less because: position of 1-pentanol.
A) the C-O bond in 2-pentanol is stronger than the C-O
bond in 1-pentanol. The answer to this question is D because the rate of substitution of protonated
B) there is a competing elimination reaction that slows the alcohols is subject to steric hindrance. This inhibits the ability of nucleophiles to
rate of substitution. collide with the reacting electrophilic center and slows the rate of reaction.
C) there is more steric hindrance at the oxygen atom in 2-
pentanol than in 1-pentanol, making protonation less
likely.
D) there is more steric hindrance at the 2-position of 2-
pentanol than at the 1-position of 1-pentanol.
If a solution containing the compounds shown in Figure B) Methyl-2-butene
4, is injected into a gas-liquid chromatograph, the first
peak observed in the gc trace is attributable to which The answer to this question is B because 2-methyl-2-butene will exhibit the lowest
compound? molecular weight and also the weakest intermolecular forces of attraction. This
A) Methyl-2-butanol substance will therefore migrate the fastest and be the first peak in the gas
B) Methyl-2-butene chromatograph (gc) trace.
C) Chloro-2-methylbutane
D) Bromo-2-mehtylbutane
R vs. S stereochemistry* R = clockwise
C = counter-clockwise
,Acetic acid and ethanol react to form an ester product as D) Replace the hydroxyl oxygen of ethanol with O-18.
shown below.
The answer to this question is D because this experiment involves labeling a group
In determining which reactant loses the -OH group, which does not exchange with other groups present prior to reaction and will
which of the following isotopic substitutions would be therefore give information about the true identity of the groups, which are
most useful? exchanged during the reaction.
A) Replace the acidic H of acetic acid with D
B) Replace the alcoholic H of ethanol with D.
C) Replace the carbonyl oxygen of acetic acid with O-18.
D) Replace the hydroxyl oxygen of ethanol with O-18.
A person whose eye has a lens-to-retina distance of 2.0 C) 51 D
cm, can only clearly see objects that are closer than 1.0 m
away. What is the strength S of the person's eye lens? The answer to this question is C because the strength of the eye lens is equal to
(Note: Use the thin lens formula 1/O + 1/I = S) the inverse of the focal length of the eye lens. Its numerical value is given by (1
m)-1+(0.02 m)-1=1 D+50 D=51 D.
A) -50 D
B) -10 D
C) 51 D
D) 55 D
Which statement correctly describes how enzymes affect D) the transition state changes the activation energy of the reaction.
chemical reactions? Stabilization of:
The answer is D because the stabilization of the transition state, not the substrate,
A) the substrate changes the free energy of the reaction. provides binding energy that is used to lower the activation energy.
B) the transition state changes the free energy of the
reaction.
C) the substrate changes the activation energy of the
reaction.
D) the transition state changes the activation energy of
the reaction.
Which of the following will decrease the percentage C) Adding concentrated HCl (aq)
ionization of 1.0 M acetic acid, CH3CO2H(aq)?*
The answer to this question is C because HCl is a strong acid that will increase the
A) Chlorinating the CH3 group amount of H+ in solution and thus decrease the percentage of CH3CO2H that
B) Diluting the solution ionizes.
C) Adding concentrated HCl (aq)
D) Adding a drop of basic indicator
When the current in the micro-robot's circuit increases B) increases
and the resistance of the circuit remains constant, the
voltage of the circuit: V = IR
A) decreases
B) increases The answer to this question is B because according to Ohm's law, current is equal
C) is constant to voltage divided by resistance. If current increases and resistance is constant,
D) is zero then voltage increases as well.
, Knowing that the speed of light in the vitreous humor is B) 1.4
2.1 × 108 m/s, what is the index of refraction of the vitreous
humor? (Note: The speed of light in a vacuum is 3.0 × 108 n = c/v
m/s.)
A) 0.7 The answer to this question is B because the index of refraction of a medium is
B) 1.4 equal to the ratio of the speed of light in vacuum to the speed of light in the
C) 2.1 medium, thus it is equal to (3.0 x 108 m/s)/(2.1 x 108 m/s) = 1.4.
D) 3.0
The intensity of the radiation emitted by the oxygen D) number of photons emitted
sensor is directly proportional to the:
The answer to this question is D because the energy of electromagnetic radiation
A) propagation speed of the radiation is directly proportional to the number of photons, and the intensity of
B) wavelength of the radiation electromagnetic radiation is defined as energy emitted per unit time. Thus,
C) polarization of photons emitted intensity is directly proportional to the number of photons emitted.
D) number of photons emitted
What is the energy of the photons emitted by the LED at D) 4.0 × 10-19 J
a frequency of 610 THz? (Note: h = 6.6 × 10-34 J·s)
The answer to this question is D because the energy of a photon of frequency 610
A) 9.2 × 10-12 J THz is equal to 6.6 x 10-34 J•s x 610 x 1012 Hz = 4 x 10-19 J.
B) 1.6 × 10-16 J
C) 1.1 × 10-18 J
D) 4.0 × 10-19 J
What percentage of standard atmospheric pressure is the B) 6%
pulse pressure of a healthy adult?
The answer to this question is B because the pulse pressure in a healthy adult is
The maximum and minimum blood pressures of a healthy (120 − 75) mmHg = 45 mmHg, and so the percentage is 45 mmHg/760 mmHg =
adult are about Ps = 120 mmHg and Pd = 75 mmHg. 6%.
Pp = Ps-Pd
A) 10%
B) 6%
C) 2%
D) 1%
What fraction of a O-15 sample decays in 10 min? D) 31/32
"The location of internal organs where changes in the The answer to this question is D because the half-life of 15O is 2 minutes; thus, 10
calcium content occur can be found by placing positron- minutes = 5 half-lives. Therefore, only (1/2)5 = 1/32 of the sample will be left after
emitting isotopes such as O-15 (with a half-life = 2 min) 10 minutes, while 31/32 of the sample will decay.
into the patient's bloodstream)
A) 1/8
B) 9/16
C) 3/4
D) 31/32
COMPLETE STUDY GUIDE WITH
PRACTICE QUESTIONS AND VERIFIED
ANSWERS| GRADED A+ | GUARANTEED
SUCCESS
Updated 2026 Questions and Answers | 100% Verified
Exam Prep and Comprehensive Rationales Included
,According to the developed chromatography plate The answer to this question is A (0.20) because Rf is the ratio of the distance
shown below, what is the approximate Rf value of travelled by the analyte relative to the solvent front during a chromatographic
aspartic acid? separation. Aspartic acid travelled two units, while the solvent front travelled ten
units, giving an Rf of 2/10 = 0.20 for aspartic acid.
aspartic acid = 2
solvent front = 10
A) 0.20
B) 0.50
C) 5
D) 10
Which of the following statements does NOT correctly D) The reaction is stereospecific.
describe the dehydration of malic acid to fumaric acid
and maleic acid? The answer to this question is D because the fact that both fumaric and maleic
acid are produced means that the dehydration of malic acid is NOT stereospecific.
A) The reaction occurs most readily with tertiary alcohols.
B) The reaction involves the loss of a water molecule.
C) The reaction has a carbocation intermediate.
D) The reaction is stereospecific.
What type of functional group is formed when aspartic C) An amide group
acid reacts with another amino acid to form a peptide
bond? The answer to this question is C because the functional group that forms during
peptide bond formation is known as an amide group.
A) An amine group
B) An aldehyde group
C) An amide group
D) A carboxyl group
If 2-pentanol replaces 1-pentanol in the reaction shown in D) there is more steric hindrance at the 2-position of 2-pentanol than at the 1-
Figure 3 (SN2), the rate of substitution is less because: position of 1-pentanol.
A) the C-O bond in 2-pentanol is stronger than the C-O
bond in 1-pentanol. The answer to this question is D because the rate of substitution of protonated
B) there is a competing elimination reaction that slows the alcohols is subject to steric hindrance. This inhibits the ability of nucleophiles to
rate of substitution. collide with the reacting electrophilic center and slows the rate of reaction.
C) there is more steric hindrance at the oxygen atom in 2-
pentanol than in 1-pentanol, making protonation less
likely.
D) there is more steric hindrance at the 2-position of 2-
pentanol than at the 1-position of 1-pentanol.
If a solution containing the compounds shown in Figure B) Methyl-2-butene
4, is injected into a gas-liquid chromatograph, the first
peak observed in the gc trace is attributable to which The answer to this question is B because 2-methyl-2-butene will exhibit the lowest
compound? molecular weight and also the weakest intermolecular forces of attraction. This
A) Methyl-2-butanol substance will therefore migrate the fastest and be the first peak in the gas
B) Methyl-2-butene chromatograph (gc) trace.
C) Chloro-2-methylbutane
D) Bromo-2-mehtylbutane
R vs. S stereochemistry* R = clockwise
C = counter-clockwise
,Acetic acid and ethanol react to form an ester product as D) Replace the hydroxyl oxygen of ethanol with O-18.
shown below.
The answer to this question is D because this experiment involves labeling a group
In determining which reactant loses the -OH group, which does not exchange with other groups present prior to reaction and will
which of the following isotopic substitutions would be therefore give information about the true identity of the groups, which are
most useful? exchanged during the reaction.
A) Replace the acidic H of acetic acid with D
B) Replace the alcoholic H of ethanol with D.
C) Replace the carbonyl oxygen of acetic acid with O-18.
D) Replace the hydroxyl oxygen of ethanol with O-18.
A person whose eye has a lens-to-retina distance of 2.0 C) 51 D
cm, can only clearly see objects that are closer than 1.0 m
away. What is the strength S of the person's eye lens? The answer to this question is C because the strength of the eye lens is equal to
(Note: Use the thin lens formula 1/O + 1/I = S) the inverse of the focal length of the eye lens. Its numerical value is given by (1
m)-1+(0.02 m)-1=1 D+50 D=51 D.
A) -50 D
B) -10 D
C) 51 D
D) 55 D
Which statement correctly describes how enzymes affect D) the transition state changes the activation energy of the reaction.
chemical reactions? Stabilization of:
The answer is D because the stabilization of the transition state, not the substrate,
A) the substrate changes the free energy of the reaction. provides binding energy that is used to lower the activation energy.
B) the transition state changes the free energy of the
reaction.
C) the substrate changes the activation energy of the
reaction.
D) the transition state changes the activation energy of
the reaction.
Which of the following will decrease the percentage C) Adding concentrated HCl (aq)
ionization of 1.0 M acetic acid, CH3CO2H(aq)?*
The answer to this question is C because HCl is a strong acid that will increase the
A) Chlorinating the CH3 group amount of H+ in solution and thus decrease the percentage of CH3CO2H that
B) Diluting the solution ionizes.
C) Adding concentrated HCl (aq)
D) Adding a drop of basic indicator
When the current in the micro-robot's circuit increases B) increases
and the resistance of the circuit remains constant, the
voltage of the circuit: V = IR
A) decreases
B) increases The answer to this question is B because according to Ohm's law, current is equal
C) is constant to voltage divided by resistance. If current increases and resistance is constant,
D) is zero then voltage increases as well.
, Knowing that the speed of light in the vitreous humor is B) 1.4
2.1 × 108 m/s, what is the index of refraction of the vitreous
humor? (Note: The speed of light in a vacuum is 3.0 × 108 n = c/v
m/s.)
A) 0.7 The answer to this question is B because the index of refraction of a medium is
B) 1.4 equal to the ratio of the speed of light in vacuum to the speed of light in the
C) 2.1 medium, thus it is equal to (3.0 x 108 m/s)/(2.1 x 108 m/s) = 1.4.
D) 3.0
The intensity of the radiation emitted by the oxygen D) number of photons emitted
sensor is directly proportional to the:
The answer to this question is D because the energy of electromagnetic radiation
A) propagation speed of the radiation is directly proportional to the number of photons, and the intensity of
B) wavelength of the radiation electromagnetic radiation is defined as energy emitted per unit time. Thus,
C) polarization of photons emitted intensity is directly proportional to the number of photons emitted.
D) number of photons emitted
What is the energy of the photons emitted by the LED at D) 4.0 × 10-19 J
a frequency of 610 THz? (Note: h = 6.6 × 10-34 J·s)
The answer to this question is D because the energy of a photon of frequency 610
A) 9.2 × 10-12 J THz is equal to 6.6 x 10-34 J•s x 610 x 1012 Hz = 4 x 10-19 J.
B) 1.6 × 10-16 J
C) 1.1 × 10-18 J
D) 4.0 × 10-19 J
What percentage of standard atmospheric pressure is the B) 6%
pulse pressure of a healthy adult?
The answer to this question is B because the pulse pressure in a healthy adult is
The maximum and minimum blood pressures of a healthy (120 − 75) mmHg = 45 mmHg, and so the percentage is 45 mmHg/760 mmHg =
adult are about Ps = 120 mmHg and Pd = 75 mmHg. 6%.
Pp = Ps-Pd
A) 10%
B) 6%
C) 2%
D) 1%
What fraction of a O-15 sample decays in 10 min? D) 31/32
"The location of internal organs where changes in the The answer to this question is D because the half-life of 15O is 2 minutes; thus, 10
calcium content occur can be found by placing positron- minutes = 5 half-lives. Therefore, only (1/2)5 = 1/32 of the sample will be left after
emitting isotopes such as O-15 (with a half-life = 2 min) 10 minutes, while 31/32 of the sample will decay.
into the patient's bloodstream)
A) 1/8
B) 9/16
C) 3/4
D) 31/32
