Practice Review Guide with Core
Content Coverage | Grade A+
• Selective Estrogen Receptor Modulators (SERMs) -✓✓Tamoxifen, toremifene,
raloxifene -- provide estrogen benefits while avoiding its drawbacks
• Dysfunctional uterine bleeding -✓✓10-14 day course of progestin
• Amenorrhea treatment -✓✓progestin helps induce menstrual flow
• Amenorrhea estrogen levels are low -✓✓give progestin for 5-10 days
• Long term progestin therapy -✓✓protection against endometrial cancer
• Estradiol -✓✓most active estrogenic compound. oral estrogen option
• Advantages of estrogen transdermal patch -✓✓lower total estrogen dose. less
n/v. less fluctuation of estrogen blood levels. lower r/f DVT, PE and stroke
• Femring -✓✓intravaginal ring controls hot flashes and night sweats. Treats
vulval and vaginal atrophy
• No gap method of changing from one OC to another -✓✓go straight from one
type of OC to the other without taking a gap.
, • initiating OC treatment -✓✓first day of menstrual cycle (no backup BC needed)
OR first sunday after onset of menses (backup BC needed for 7 days)
• Initiating androgen therapy short term -✓✓delayed sexual maturation causing a
boy significant distress. Limited course of Fluoxymesterone and
methyltestosterone are approved.
• androgen therapy long term -✓✓if delayed puberty is the result of true
hypogonadism
• role of androgens in anemia -✓✓promote synthesis of erythropoietin the renal
hormone that stimulates production of RBCs
• Alprostadil preferred administration -✓✓direct injection into the corpus
cavernosum. Rapid response
• Finasteride -✓✓BPH tx 5a reductase inhibitor. Causes prostate to shrink.
benefits take months
• Tamsulosin -✓✓BPH tx alpha adrenergic antagonist. relaxes smooth muscle.
benefits are rapid
• Adverse effects of silodosin and tamsulosin -✓✓r/f floppy iris syndrome during
cataract surgery.
• Chlamydia tx -✓✓azithromycin 1g PO x single dose. doxycycline 100mg PO
BID 7 days