NURS 615 ADV PHARM CERTIFICATION
EVALUATION QUESTIONS AND DETAILED
SOLUTIONS
●● acetaminophen
Answer: centrally acting cox inhibitor; analgesic and antipyretic
properties; no antiinflammatory,antirheumatic properties
●● acyclovir
Answer: Antimetabolite for Treating Herpes Simplex Virus & Varicella-
Zoster Virus Infections;
MOAs: Purine necleoside analog: DNA polymerase inhibitor, suppresses
synthesis of viral DNA, resistance.
●● amiodarone
Answer: Class 3 Potassium channel blocker
Only approved for life-threatening dysrhythmias.
Delays repolarization and extends action potential of heart muscle cells.
SE: Profound hypotension."
●● amoxicillin
,Answer: Broad-spectrum penicillin active against H. influenzae, E. coli,
and N. Gonorrhoeae. It is inactivated by beta-lactamases, so not helpful
for Staphylococcus.
●● atropine
Answer: muscinarinic receptor antagonist/anticholinergic drug; used for
mydriases (eye exams), to raise HR, lower GI motility, and as antidote to
muscarinic poisoning (rx, shrooms)
●● amphotericin B
Answer: broad spectrum antifungal, which is the agent of choice for
systemic mycoses, despite being highly toxic. Its uses are limited to
treating progressive and potentially fatal infections. Adverse effects
include infusion reactions, nephrotoxicity, and hypokalemia.
●● aspirin
Answer: A drug that decrease platelet aggregation and is used to prevent
arterial thrombosis, stroke, or MI. Major SEs include risk of major GI
bleeding. This drug is an NSAID that works by inhibiting platelet COX,
COX-1, and COX-2.
●● beclomethasone
Answer: inhaled corticosteroid used to treat airway inflammation in
asthma
, ●● bethanechol
Answer: muscarinic agnonist, used primarily for urinary retention
●● buproprion
Answer: (DA and NE). Weight loss, seizure, insomnia, headache,
serotonin syndrome (see laundry list above), withdrawal, Neonatal
Abstinence Syndrome
●● captopril
Answer: ACE inhibitor - shown to have efficacious effects in treating a
patient with heart failure. Blocks production of angiotensin II, dilates
arterioles and veins, and decreases release of aldosterone. It may show
the adverse effects of hypotension, hyperkalemia, or persistant cough,
CARDIAC REMODELING
●● carbenicillin
Answer: "Extended spectrum (antipseudomonal penicillins), which has
the same spectrum of activity as broad-spectrum penicillins, plus
treatment of Pseudomonas aeruginosa
●● cefotaxime
Answer: "Third generation cephalosporin with activity against
meningitis and nosocomial infections resistant to others (restricted use).
It has greater activity against Gram negative bacteria, increased
resistance to beta-lactamases, and better ability to reach CSF.
EVALUATION QUESTIONS AND DETAILED
SOLUTIONS
●● acetaminophen
Answer: centrally acting cox inhibitor; analgesic and antipyretic
properties; no antiinflammatory,antirheumatic properties
●● acyclovir
Answer: Antimetabolite for Treating Herpes Simplex Virus & Varicella-
Zoster Virus Infections;
MOAs: Purine necleoside analog: DNA polymerase inhibitor, suppresses
synthesis of viral DNA, resistance.
●● amiodarone
Answer: Class 3 Potassium channel blocker
Only approved for life-threatening dysrhythmias.
Delays repolarization and extends action potential of heart muscle cells.
SE: Profound hypotension."
●● amoxicillin
,Answer: Broad-spectrum penicillin active against H. influenzae, E. coli,
and N. Gonorrhoeae. It is inactivated by beta-lactamases, so not helpful
for Staphylococcus.
●● atropine
Answer: muscinarinic receptor antagonist/anticholinergic drug; used for
mydriases (eye exams), to raise HR, lower GI motility, and as antidote to
muscarinic poisoning (rx, shrooms)
●● amphotericin B
Answer: broad spectrum antifungal, which is the agent of choice for
systemic mycoses, despite being highly toxic. Its uses are limited to
treating progressive and potentially fatal infections. Adverse effects
include infusion reactions, nephrotoxicity, and hypokalemia.
●● aspirin
Answer: A drug that decrease platelet aggregation and is used to prevent
arterial thrombosis, stroke, or MI. Major SEs include risk of major GI
bleeding. This drug is an NSAID that works by inhibiting platelet COX,
COX-1, and COX-2.
●● beclomethasone
Answer: inhaled corticosteroid used to treat airway inflammation in
asthma
, ●● bethanechol
Answer: muscarinic agnonist, used primarily for urinary retention
●● buproprion
Answer: (DA and NE). Weight loss, seizure, insomnia, headache,
serotonin syndrome (see laundry list above), withdrawal, Neonatal
Abstinence Syndrome
●● captopril
Answer: ACE inhibitor - shown to have efficacious effects in treating a
patient with heart failure. Blocks production of angiotensin II, dilates
arterioles and veins, and decreases release of aldosterone. It may show
the adverse effects of hypotension, hyperkalemia, or persistant cough,
CARDIAC REMODELING
●● carbenicillin
Answer: "Extended spectrum (antipseudomonal penicillins), which has
the same spectrum of activity as broad-spectrum penicillins, plus
treatment of Pseudomonas aeruginosa
●● cefotaxime
Answer: "Third generation cephalosporin with activity against
meningitis and nosocomial infections resistant to others (restricted use).
It has greater activity against Gram negative bacteria, increased
resistance to beta-lactamases, and better ability to reach CSF.
