lOMoARcPSD|44532475
Pharmacology Exam 1 - This is a study guide for exam 1.
Principles Of Pharmacology (Galen College of Nursing)
Scan to open on Studocu
Studocu is not sponsored or endorsed by any college or university
Downloaded by madiba South Africa stuvia ()
, lOMoARcPSD|44532475
1
Pharmacology Exam 1
Unit 1
o Know the pharmacology terms: Definition (So what) and
significance (Now what or why is it important)
Half-life: time required for the body to eliminate
half of the drug. (if the patient has poor kidney function
this can increase the half-life of the medication)
Significance: determines the frequency for dosing.
o Understand protein binding of drugs, (we check albumin (3.5-5)
levels in regard to protein binding)
o Primary effect = the desirable response (does what it is
supposed to do)
o Secondary effect = desirable or undesirable (what it does &
what happens after
o Therapeutic index = the relationship between the therapeutic
dose and toxic dose
Therapeutic index = close monitoring of patient via labs
o Peak = highest concentration of the drug in the blood,
performed shortly after med has infused. The drug has to be in
their system in order to do this test, otherwise you are poking
them with a needle for no reason.
Significance: guide assessment of therapeutic effects and
planning for next dose.
o Trough = lowest concentration, ordered before the next dose of
med is due
A peak and trough is a lab blood test, you have to have the
drug in your system.
Significance: indicates if dose prescribed is effective.
o Agonist = activate receptors = desired effect
o Antagonist = prevent receptor activation = block response
Ex: Narcan against opioids
Significance: space out medications to avoid blocking the
effects of the initial med. Monitor for changes in
medication effectiveness.
o Side effects = secondary effects
Significance: this guides our assessments and teaching.
o Adverse drug reaction = unintentional, unexpected at a
normal dose.
Significance: identify early to discontinue med – guides
assessment.
Downloaded by madiba South Africa stuvia ()
Pharmacology Exam 1 - This is a study guide for exam 1.
Principles Of Pharmacology (Galen College of Nursing)
Scan to open on Studocu
Studocu is not sponsored or endorsed by any college or university
Downloaded by madiba South Africa stuvia ()
, lOMoARcPSD|44532475
1
Pharmacology Exam 1
Unit 1
o Know the pharmacology terms: Definition (So what) and
significance (Now what or why is it important)
Half-life: time required for the body to eliminate
half of the drug. (if the patient has poor kidney function
this can increase the half-life of the medication)
Significance: determines the frequency for dosing.
o Understand protein binding of drugs, (we check albumin (3.5-5)
levels in regard to protein binding)
o Primary effect = the desirable response (does what it is
supposed to do)
o Secondary effect = desirable or undesirable (what it does &
what happens after
o Therapeutic index = the relationship between the therapeutic
dose and toxic dose
Therapeutic index = close monitoring of patient via labs
o Peak = highest concentration of the drug in the blood,
performed shortly after med has infused. The drug has to be in
their system in order to do this test, otherwise you are poking
them with a needle for no reason.
Significance: guide assessment of therapeutic effects and
planning for next dose.
o Trough = lowest concentration, ordered before the next dose of
med is due
A peak and trough is a lab blood test, you have to have the
drug in your system.
Significance: indicates if dose prescribed is effective.
o Agonist = activate receptors = desired effect
o Antagonist = prevent receptor activation = block response
Ex: Narcan against opioids
Significance: space out medications to avoid blocking the
effects of the initial med. Monitor for changes in
medication effectiveness.
o Side effects = secondary effects
Significance: this guides our assessments and teaching.
o Adverse drug reaction = unintentional, unexpected at a
normal dose.
Significance: identify early to discontinue med – guides
assessment.
Downloaded by madiba South Africa stuvia ()
