7) HEMATOLOGIC PATHOPHYSIOLOGY
# TERM DEFINITION
1 what causes impaired RBC
production? -kidney failure leads to decreased
erythropoietin secretions that
stimulation bone marrow to
produce
RBC
-nutritional deficiencies vit b12,
iron
-inflammatory diseases
2 sickle cell anemia
-autosomal recessive -rbc
with hemoglobin S sickle
when deoxygenated
, 3 sickle cell key indicator and s/s
key indicator: generalized
pain everywhere s/s: low
grade fever, bone/joint pain,
priapism, pinpoint pupils,
photophobia
4 sickle cell diagosis
sickle cells present on blood
smear, elevated reticulocyte
count, elevated WBC
5 sickle cell medical
management prevention, teaching. pain
management, PRBC, bone
marrow transplant teaching:
stay hydrated, avoid hot/cold
extremes, stop smoking, med
bracelet
# TERM DEFINITION
1 what causes impaired RBC
production? -kidney failure leads to decreased
erythropoietin secretions that
stimulation bone marrow to
produce
RBC
-nutritional deficiencies vit b12,
iron
-inflammatory diseases
2 sickle cell anemia
-autosomal recessive -rbc
with hemoglobin S sickle
when deoxygenated
, 3 sickle cell key indicator and s/s
key indicator: generalized
pain everywhere s/s: low
grade fever, bone/joint pain,
priapism, pinpoint pupils,
photophobia
4 sickle cell diagosis
sickle cells present on blood
smear, elevated reticulocyte
count, elevated WBC
5 sickle cell medical
management prevention, teaching. pain
management, PRBC, bone
marrow transplant teaching:
stay hydrated, avoid hot/cold
extremes, stop smoking, med
bracelet
